ID X2JFP6_DROME Unreviewed; 815 AA. AC X2JFP6; DT 11-JUN-2014, integrated into UniProtKB/TrEMBL. DT 11-JUN-2014, sequence version 1. DT 07-NOV-2018, entry version 42. DE SubName: Full=Rab11 interacting protein, isoform E {ECO:0000313|EMBL:AHN59883.1}; GN Name=Rip11 {ECO:0000313|EMBL:AHN59883.1, GN ECO:0000313|FlyBase:FBgn0027335}; GN Synonyms=Dmel\CG6606 {ECO:0000313|EMBL:AHN59883.1}, dRip11 GN {ECO:0000313|EMBL:AHN59883.1}, l(1)G0003 GN {ECO:0000313|EMBL:AHN59883.1}, l(1)G0070 GN {ECO:0000313|EMBL:AHN59883.1}, l(1)G0092 GN {ECO:0000313|EMBL:AHN59883.1}, l(1)G0205 GN {ECO:0000313|EMBL:AHN59883.1}, l(1)G0297 GN {ECO:0000313|EMBL:AHN59883.1}, l(1)G0434 GN {ECO:0000313|EMBL:AHN59883.1}; GN ORFNames=CG6606 {ECO:0000313|EMBL:AHN59883.1, GN ECO:0000313|FlyBase:FBgn0027335}, Dmel_CG6606 GN {ECO:0000313|EMBL:AHN59883.1}; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227 {ECO:0000313|EMBL:AHN59883.1, ECO:0000313|Proteomes:UP000000803}; RN [1] {ECO:0000313|EMBL:AHN59883.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., RA Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., RA Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., RA Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [2] {ECO:0000313|EMBL:AHN59883.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537568; RA Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., RA Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., RA George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., RA Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J., RA Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., RA Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.; RT "Finishing a whole-genome shotgun: release 3 of the Drosophila RT melanogaster euchromatic genome sequence."; RL Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002). RN [3] {ECO:0000313|EMBL:AHN59883.1, ECO:0000313|Proteomes:UP000000803} RP GENOME REANNOTATION. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfied E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). RN [4] {ECO:0000313|EMBL:AHN59883.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537573; RA Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., RA Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., RA Ashburner M., Celniker S.E.; RT "The transposable elements of the Drosophila melanogaster euchromatin: RT a genomics perspective."; RL Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002). RN [5] {ECO:0000313|EMBL:AHN59883.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537574; RA Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., RA Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., RA Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., RA Karpen G.H.; RT "Heterochromatic sequences in a Drosophila whole-genome shotgun RT assembly."; RL Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002). RN [6] {ECO:0000313|EMBL:AHN59883.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=16110336; DOI=10.1371/journal.pcbi.0010022; RA Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., RA Ashburner M., Anxolabehere D.; RT "Combined evidence annotation of transposable elements in genome RT sequences."; RL PLoS Comput. Biol. 1:166-175(2005). RN [7] {ECO:0000313|EMBL:AHN59883.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569856; DOI=10.1126/science.1139815; RA Smith C.D., Shu S., Mungall C.J., Karpen G.H.; RT "The Release 5.1 annotation of Drosophila melanogaster RT heterochromatin."; RL Science 316:1586-1591(2007). RN [8] {ECO:0000313|EMBL:AHN59883.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569867; DOI=10.1126/science.1139816; RA Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M., RA Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A., RA Dimitri P., Karpen G.H., Celniker S.E.; RT "Sequence finishing and mapping of Drosophila melanogaster RT heterochromatin."; RL Science 316:1625-1628(2007). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE014298; AHN59883.1; -; Genomic_DNA. DR RefSeq; NP_001285413.1; NM_001298484.1. DR UniGene; Dm.208; -. DR ProteinModelPortal; X2JFP6; -. DR SMR; X2JFP6; -. DR PRIDE; X2JFP6; -. DR EnsemblMetazoa; FBtr0343021; FBpp0309773; FBgn0027335. DR GeneID; 32850; -. DR CTD; 32850; -. DR FlyBase; FBgn0027335; Rip11. DR eggNOG; ENOG410IEZZ; Eukaryota. DR eggNOG; ENOG410Z26C; LUCA. DR GeneTree; ENSGT00530000063203; -. DR OrthoDB; EOG091G09IV; -. DR ChiTaRS; Rip11; fly. DR GenomeRNAi; 32850; -. DR Proteomes; UP000000803; Chromosome X. DR Bgee; FBgn0027335; Expressed in 34 organ(s), highest expression level in embryonic/larval hemocyte (Drosophila). DR ExpressionAtlas; X2JFP6; baseline and differential. DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central. DR GO; GO:0017137; F:Rab GTPase binding; IPI:FlyBase. DR GO; GO:0045055; P:regulated exocytosis; IBA:GO_Central. DR GO; GO:0042052; P:rhabdomere development; IMP:FlyBase. DR Gene3D; 2.60.40.150; -; 1. DR InterPro; IPR000008; C2_dom. DR InterPro; IPR035892; C2_domain_sf. DR InterPro; IPR037245; FIP-RBD_C_sf. DR InterPro; IPR037789; FIP_classI. DR InterPro; IPR019018; Rab-bd_FIP-RBD. DR PANTHER; PTHR15746; PTHR15746; 1. DR Pfam; PF00168; C2; 1. DR Pfam; PF09457; RBD-FIP; 1. DR SMART; SM00239; C2; 1. DR SUPFAM; SSF144270; SSF144270; 1. DR PROSITE; PS51511; FIP_RBD; 1. PE 1: Evidence at protein level; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Complete proteome {ECO:0000313|Proteomes:UP000000803}; KW Proteomics identification {ECO:0000213|PeptideAtlas:X2JFP6}; KW Reference proteome {ECO:0000313|Proteomes:UP000000803}. FT DOMAIN 743 805 FIP-RBD. {ECO:0000259|PROSITE:PS51511}. FT COILED 552 615 {ECO:0000256|SAM:Coils}. SQ SEQUENCE 815 AA; 89749 MW; E26F0363E8ADFE4F CRC64; MWSPTHCSVT VQRARGLLTK GKNGTNNCFV TIALGKEKYQ TSVKDKAETS VNWNEECELK IPDQGNRAEL TLTCLHRNNL GIDEFLGQAT LPLNEMDVYD RPRAKWFKLE SKPGKEKKNK ERGELEVRIA FVVKSGSLTD LSKKDKHKSS IGQLASSVGG SLLSIGNGEK RRGIKKLAGS LSSKLHIRSK KKNQEAGADD SSSFGGSFAS LGTPNSSNGR GQNGGSGRRR GGQRAGEADP GVISEDEDEF VFDNLSHKSS GSSLNIQRIG LQPPPVGTPN FTPRHPSPLL NNGVSGVGSG SAKGKQAVLP ATLDEDASID AEMEQLELDF SVRAHARANA NASASGNAST LPPPSKPPRI PLSQVDEQPA AGSLEREKPK EKPAEVESDK DEWASKLYGG GKYLEIGSSN SLKRRSWEDR VPLPASVEEP PPLHSSSSSS SSSSDSDDDD EKPPQAAPPP VPVPASLPVP SAAASTASAD PVVATSSSLF SPDVEHRNFD TFNASFAKYE QRNSTAIFAD EPELEDLTVE LEKPAPTPTA RPKPQPRATA DLRAEEEKAK EEAARQLRAE EDARLEAELR LNEERLREEE EAMQRELEEE KERQKQLQMD EQQRREAKRW EEDQRLLSFA KRSTSLEEPV PEKQELKHER ELVAKQEPEK TLDTAEPEPE HNFLTPEQSP KEFQTNGSGS GSGERWEKRL GKFKYGNKRD KYNNDNDSNS PSPKSTERII IGHEKSGSHA DRRSEISAQL AKKYEGKSRE ELMLIANGME NEALLQRQRV KELEDYLDNL LLRVMETHPK ILQNPYSRTT SAKSG //