ID X1WG47_DANRE Unreviewed; 196 AA. AC X1WG47; DT 14-MAY-2014, integrated into UniProtKB/TrEMBL. DT 14-MAY-2014, sequence version 1. DT 18-JAN-2017, entry version 14. DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSDARP00000129202}; GN Name=il12a {ECO:0000313|Ensembl:ENSDARP00000129202, GN ECO:0000313|ZFIN:ZDB-GENE-060724-1}; OS Danio rerio (Zebrafish) (Brachydanio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000129202, ECO:0000313|Proteomes:UP000000437}; RN [1] {ECO:0000313|Ensembl:ENSDARP00000129202, ECO:0000313|Proteomes:UP000000437} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000129202, RC ECO:0000313|Proteomes:UP000000437}; RX PubMed=23594743; DOI=10.1038/nature12111; RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., RA Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., RA McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., RA Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T., RA Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., RA Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., RA Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., RA Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G., RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P., RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., RA Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., RA Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., RA Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., RA Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., RA Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., RA Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., RA Murnane C., Gray E., Humphries M., Sycamore N., Barker D., RA Saunders D., Wallis J., Babbage A., Hammond S., RA Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., RA Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., RA Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., RA Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., RA Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., RA Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., RA Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., RA Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., RA Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., RA Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., RA Stemple D.L.; RT "The zebrafish reference genome sequence and its relationship to the RT human genome."; RL Nature 496:498-503(2013). RN [2] {ECO:0000313|Ensembl:ENSDARP00000129202} RP IDENTIFICATION. RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000129202}; RG Ensembl; RL Submitted (MAR-2014) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSDARP00000129202}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CT027672; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR RefSeq; NP_001007108.2; NM_001007107.2. DR UniGene; Dr.162019; -. DR PaxDb; X1WG47; -. DR Ensembl; ENSDART00000153685; ENSDARP00000129202; ENSDARG00000038878. DR GeneID; 445410; -. DR KEGG; dre:445410; -. DR CTD; 3592; -. DR ZFIN; ZDB-GENE-060724-1; il12a. DR eggNOG; ENOG410JN8M; Eukaryota. DR eggNOG; ENOG4111B33; LUCA. DR GeneTree; ENSGT00530000064915; -. DR KO; K05406; -. DR Proteomes; UP000000437; Chromosome 15. DR ExpressionAtlas; X1WG47; baseline. DR GO; GO:0005576; C:extracellular region; IEA:InterPro. DR GO; GO:0006955; P:immune response; IEA:InterPro. DR GO; GO:0043330; P:response to exogenous dsRNA; IDA:ZFIN. DR GO; GO:0032496; P:response to lipopolysaccharide; IDA:ZFIN. DR GO; GO:0002237; P:response to molecule of bacterial origin; IDA:ZFIN. DR Gene3D; 1.20.1250.10; -; 1. DR InterPro; IPR009079; 4_helix_cytokine-like_core. DR InterPro; IPR012351; 4_helix_cytokine_core. DR InterPro; IPR004281; IL-12_alpha. DR PANTHER; PTHR10523; PTHR10523; 1. DR SUPFAM; SSF47266; SSF47266; 1. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000000437}; KW Reference proteome {ECO:0000313|Proteomes:UP000000437}; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1 16 {ECO:0000256|SAM:SignalP}. FT CHAIN 17 196 {ECO:0000256|SAM:SignalP}. FT /FTId=PRO_5004949003. SQ SEQUENCE 196 AA; 21586 MW; 423B570085CB8820 CRC64; MKICIVISMA LALALCSPVP PPDSQECVCS PAARSLLSAL THIMEKEGKM KEQDLFAGFN CTDLEAQMTP HTHTSSVCQP SVSANSSCSA HRSSNFSAVE CVKNIRGDLR YYDLLLNSYK PSTQELSPVI TANTQLINCL NQRCESAEGV FPQWRVWKGS SFDDRVSLCK TLKGFHIRSI TVNRALAYIA SGEHRK //