ID W8JCU2_PAPDA Unreviewed; 310 AA. AC W8JCU2; DT 14-MAY-2014, integrated into UniProtKB/TrEMBL. DT 14-MAY-2014, sequence version 1. DT 31-JUL-2019, entry version 13. DE RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; DE EC=7.1.1.2 {ECO:0000256|RuleBase:RU000473}; GN Name=ND1 {ECO:0000313|EMBL:AHK61036.1}; OS Papilio dardanus (African swallowtail butterfly). OG Mitochondrion {ECO:0000313|EMBL:AHK61036.1}. OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Holometabola; Lepidoptera; Glossata; Ditrysia; OC Papilionoidea; Papilionidae; Papilioninae; Papilio. OX NCBI_TaxID=77259 {ECO:0000313|EMBL:AHK61036.1}; RN [1] {ECO:0000313|EMBL:AHK61036.1} RP NUCLEOTIDE SEQUENCE. RA Timmermans M.J.T.N., Lim J., Dodsworth S., Haran J., Ahrens D., RA Bocak L., London A., Culverwell L., Vogler A.P.; RT "Mitogenomics of the Coleoptera under dense taxon sampling."; RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: CC Reaction=a ubiquinone + 5 H(+)(in) + NADH = a ubiquinol + 4 CC H(+)(out) + NAD(+); Xref=Rhea:RHEA:29091, Rhea:RHEA-COMP:9565, CC Rhea:RHEA-COMP:9566, ChEBI:CHEBI:15378, ChEBI:CHEBI:16389, CC ChEBI:CHEBI:17976, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; CC EC=7.1.1.2; Evidence={ECO:0000256|RuleBase:RU000473}; CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane CC {ECO:0000256|RuleBase:RU000471}; Multi-pass membrane protein CC {ECO:0000256|RuleBase:RU000471}. CC -!- SIMILARITY: Belongs to the complex I subunit 1 family. CC {ECO:0000256|RuleBase:RU000471}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JX313686; AHK61036.1; -; Genomic_DNA. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:UniProtKB-EC. DR HAMAP; MF_01350; NDH1_NuoH; 1. DR InterPro; IPR001694; NADH_UbQ_OxRdtase_su1/FPO. DR InterPro; IPR018086; NADH_UbQ_OxRdtase_su1_CS. DR PANTHER; PTHR11432; PTHR11432; 1. DR Pfam; PF00146; NADHdh; 1. DR PROSITE; PS00668; COMPLEX1_ND1_2; 1. PE 3: Inferred from homology; KW Membrane {ECO:0000256|SAM:Phobius}; KW Mitochondrion {ECO:0000256|RuleBase:RU000473, KW ECO:0000313|EMBL:AHK61036.1}; NAD {ECO:0000256|RuleBase:RU000471}; KW Transmembrane {ECO:0000256|RuleBase:RU000471, KW ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}; KW Ubiquinone {ECO:0000256|RuleBase:RU000473}. FT TRANSMEM 6 25 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 74 98 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 105 125 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 145 165 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 177 196 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 225 248 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 255 271 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 291 309 Helical. {ECO:0000256|SAM:Phobius}. SQ SEQUENCE 310 AA; 35982 MW; 483C837AA9B186E4 CRC64; MYDIYMFFIG VLIMIIGVMV GVAFLTLLER QALGYIQIRK GPNKVGYMGI LQPFADVVKL FTKEQTFPNY SNYMAYYFSP ITSFIVILMS WILIPYYFNL ISFNLGILFF LCCTSVGVYT VMIAGWSSNS NYALLGGLRA VAQTISYEVS LALIMLSSII MIMSFNMINF FFYQEIIWFF FLMMPLSLCW LSSSLAETNR TPFDFAEGES ELVSGFNVEY SSGGFTLIFL SEYASILFMS MLFILLYLGG YSLSLIFYLK LSFISFMFIW VRGTLPRYRY DKLMYLSWKS YLPISLNFLL FFLGIKFFFY //