ID W8FK29_9EUPU Unreviewed; 204 AA. AC W8FK29; DT 14-MAY-2014, integrated into UniProtKB/TrEMBL. DT 14-MAY-2014, sequence version 1. DT 11-JUN-2014, entry version 2. DE RecName: Full=Cytochrome c oxidase subunit 1; DE EC=1.9.3.1; DE Flags: Fragment; GN Name=COI; OS Limax cinereoniger. OG Mitochondrion. OC Eukaryota; Metazoa; Lophotrochozoa; Mollusca; Gastropoda; OC Heterobranchia; Euthyneura; Panpulmonata; Eupulmonata; OC Stylommatophora; Sigmurethra; Limacoidea; Limacidae; Limax. OX NCBI_TaxID=665645; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=Y31; RA Rowson B., Anderson R., Turner J.A., Symondson W.O.C.; RT "The Slugs of Britain and Ireland: Undetected and Undescribed Species RT Increase a Well-studied, Economically Important Fauna by More Than RT 20%."; RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory CC chain that catalyzes the reduction of oxygen to water. Subunits 1- CC 3 form the functional core of the enzyme complex. CO I is the CC catalytic subunit of the enzyme. Electrons originating in CC cytochrome c are transferred via the copper A center of subunit 2 CC and heme A of subunit 1 to the bimetallic center formed by heme A3 CC and copper B (By similarity). CC -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4 CC ferricytochrome c + 2 H(2)O. CC -!- PATHWAY: Energy metabolism; oxidative phosphorylation. CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass CC membrane protein (By similarity). CC -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KF894380; AHK05620.1; -; Genomic_DNA. DR UniPathway; UPA00705; -. DR Gene3D; 1.20.210.10; -; 1. DR InterPro; IPR000883; Cyt_c_Oxase_su1. DR InterPro; IPR023616; Cyt_c_Oxase_su1_dom. DR PANTHER; PTHR10422; PTHR10422; 1. DR Pfam; PF00115; COX1; 1. DR PRINTS; PR01165; CYCOXIDASEI. DR SUPFAM; SSF81442; SSF81442; 1. DR PROSITE; PS50855; COX1; 1. PE 3: Inferred from homology; KW Copper; Electron transport; Heme; Iron; Membrane; Metal-binding; KW Mitochondrion; Mitochondrion inner membrane; Oxidoreductase; KW Respiratory chain; Transmembrane; Transport. FT NON_TER 1 1 FT NON_TER 204 204 SQ SEQUENCE 204 AA; 21980 MW; 0947CD62D22618F1 CRC64; VGTGLSLLIR LELGTAGVLM DDHFFNVIVT AHAFVMIFFM VMPIMIGGFG NWMVPLLIGA PDMSFPRMNN MSFWLLPPSF ILLICSSMVE GGAGTGWTVY PPLSGPLGHG GASVDLAIFS LHLAGMSSIL GAINFITTIF NMRTSGMTME RVSLFVWSIL VTVFLLLLSL PVLAGAITML LTDRNFNTSF FDPAGGGDPI LYQH //