ID W8CGX9_APICC Unreviewed; 133 AA. AC W8CGX9; DT 14-MAY-2014, integrated into UniProtKB/TrEMBL. DT 14-MAY-2014, sequence version 1. DT 20-DEC-2017, entry version 17. DE RecName: Full=Glutaredoxin {ECO:0000256|PIRNR:PIRNR005894}; GN Name=Grx2 {ECO:0000313|EMBL:AFU83107.1}; GN Synonyms=grx2 {ECO:0000313|EMBL:AFU83110.1}; OS Apis cerana cerana (Oriental honeybee). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Holometabola; Hymenoptera; Apocrita; Aculeata; OC Apoidea; Apidae; Apis. OX NCBI_TaxID=94128 {ECO:0000313|EMBL:AFU83107.1}; RN [1] {ECO:0000313|EMBL:AFU83107.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=24389255; DOI=10.1016/j.freeradbiomed.2013.12.020; RA Yao P., Chen X., Yan Y., Liu F., Zhang Y., Guo X., Xu B.; RT "Glutaredoxin 1, glutaredoxin 2, thioredoxin 1, and thioredoxin RT peroxidase 3 play important roles in antioxidant defense in Apis RT cerana cerana."; RL Free Radic. Biol. Med. 68:335-346(2014). CC -!- SIMILARITY: Belongs to the glutaredoxin family. Monothiol CC subfamily. {ECO:0000256|PIRNR:PIRNR005894}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JX844655; AFU83107.1; -; mRNA. DR EMBL; JX844658; AFU83110.1; -; Genomic_DNA. DR ProteinModelPortal; W8CGX9; -. DR GO; GO:0005623; C:cell; IEA:GOC. DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW. DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro. DR GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro. DR CDD; cd03028; GRX_PICOT_like; 1. DR InterPro; IPR002109; Glutaredoxin. DR InterPro; IPR033658; GRX_PICOT-like. DR InterPro; IPR014434; Monothiol_GRX. DR InterPro; IPR004480; Monothiol_GRX-rel. DR InterPro; IPR036249; Thioredoxin-like_sf. DR PANTHER; PTHR10293; PTHR10293; 1. DR Pfam; PF00462; Glutaredoxin; 1. DR PIRSF; PIRSF005894; Monothiol_GRX; 1. DR SUPFAM; SSF52833; SSF52833; 1. DR TIGRFAMs; TIGR00365; TIGR00365; 1. DR PROSITE; PS51354; GLUTAREDOXIN_2; 1. PE 2: Evidence at transcript level; KW 2Fe-2S {ECO:0000256|PIRSR:PIRSR005894-2}; KW Iron {ECO:0000256|PIRSR:PIRSR005894-2}; KW Iron-sulfur {ECO:0000256|PIRSR:PIRSR005894-2}; KW Metal-binding {ECO:0000256|PIRSR:PIRSR005894-2}. FT DOMAIN 16 118 Glutaredoxin. {ECO:0000259|PROSITE: FT PS51354}. FT METAL 41 41 Iron-sulfur (2Fe-2S); shared with dimeric FT partner. {ECO:0000256|PIRSR:PIRSR005894- FT 2}. SQ SEQUENCE 133 AA; 14964 MW; 267DA7394D1B3CFA CRC64; MIPFRSFIVR SFSTTSNKIA NLVKKNKVVV FMKGVPDSPK CGFSNAVVQI LRMHNVKYDA HNVLEDEQLR QGIKDFSNWP TIPQVFINGE FVGGCDILLE MHRNGELIAE LKKAGITSAL LEEDDSPEKK TKD //