ID W6PPA1_MOUSE Unreviewed; 2622 AA. AC W6PPA1; DT 16-APR-2014, integrated into UniProtKB/TrEMBL. DT 16-APR-2014, sequence version 1. DT 29-OCT-2014, entry version 5. DE SubName: Full=270-kDa ankyrinG {ECO:0000313|EMBL:CDM21876.1}; GN Name=Ank3 {ECO:0000313|EMBL:CDM21876.1}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|EMBL:CDM21876.1}; RN [1] {ECO:0000313|EMBL:CDM21876.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57Bl6 {ECO:0000313|EMBL:CDM21876.1}; RA Barbara L.; RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:CDM21876.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57Bl6 {ECO:0000313|EMBL:CDM21876.1}; RA Freal A., Le Bras B., Fassier C., Bullier E., De Gois S., Hazan J., RA Couraud F.; RT "480-kDa Ankyrin G and not its 270-kDa isoform assembles the axon RT initial segment."; RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Contains 22 ANK repeats. CC {ECO:0000256|RuleBase:RU003321}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; HG915715; CDM21876.1; -; Genomic_DNA. DR GO; GO:0007165; P:signal transduction; IEA:InterPro. DR Gene3D; 1.10.533.10; -; 1. DR Gene3D; 1.25.40.20; -; 3. DR InterPro; IPR002110; Ankyrin_rpt. DR InterPro; IPR020683; Ankyrin_rpt-contain_dom. DR InterPro; IPR011029; DEATH-like_dom. DR InterPro; IPR000488; Death_domain. DR InterPro; IPR000906; ZU5_dom. DR Pfam; PF00023; Ank; 1. DR Pfam; PF12796; Ank_2; 7. DR Pfam; PF00531; Death; 1. DR Pfam; PF00791; ZU5; 1. DR PRINTS; PR01415; ANKYRIN. DR SMART; SM00248; ANK; 22. DR SMART; SM00005; DEATH; 1. DR SMART; SM00218; ZU5; 1. DR SUPFAM; SSF47986; SSF47986; 1. DR SUPFAM; SSF48403; SSF48403; 3. DR PROSITE; PS50297; ANK_REP_REGION; 1. DR PROSITE; PS50088; ANK_REPEAT; 21. DR PROSITE; PS50017; DEATH_DOMAIN; 1. DR PROSITE; PS51145; ZU5; 1. PE 4: Predicted; KW ANK repeat {ECO:0000256|RuleBase:RU003321}; KW Repeat {ECO:0000256|RuleBase:RU003536}. SQ SEQUENCE 2622 AA; 284662 MW; AC6A1AD505BC0338 CRC64; MAHAASQLKK NRDLEINAEE ETEKKRKHRK RSRDRKKKSD ANASYLRAAR AGHLEKALDY IKNGVDVNIC NQNGLNALHL ASKEGHVEVV SELLQREANV DAATKKGNTA LHIASLAGQA EVVKVLVTNG ANVNAQSQNG FTPLYMAAQE NHLEVVRFLL DNGASQSLAT EDGFTPLAVA LQQGHDQVVS LLLENDTKGK VRLPALHIAA RKDDTKAAAL LLQNDTNADV ESKSGFTPLH IAAHYGNINV ATLLLNRAAA VDFTARNDIT PLHVASKRGN ANMVKLLLDR GAKIDAKTRD GLTPLHCGAR SGHEQVVEML LDRSAPILSK TKNGLSPLHM ATQGDHLNCV QLLLQHNVPV DDVTNDYLTA LHVAAHCGHY KVAKVLLDKK ASPNAKALNG FTPLHIACKK NRIRVMELLL KHGASIQAVT ESGLTPIHVA AFMGHVNIVS QLMHHGASPN TTNVRGETAL HMAARSGQAE VVRYLVQDGA QVEAKAKDDQ TPLHISARLG KADIVQQLLQ QGASPNAATT SGYTPLHLAA REGHEDVAAF LLDHGASLSI TTKKGFTPLH VAAKYGKLEV ASLLLQKSAS PDAAGKSGLT PLHVAAHYDN QKVALLLLDQ GASPHAAAKN GYTPLHIAAK KNQMDIATSL LEYGADANAV TRQGIASVHL AAQEGHVDMV SLLLSRNANV NLSNKSGLTP LHLAAQEDRV NVAEVLVNQG AHVDAQTKMG YTPLHVGCHY GNIKIVNFLL QHSAKVNAKT KNGYTALHQA AQQGHTHIIN VLLQNNASPN ELTVNGNTAL AIARRLGYIS VVDTLKVVTE EIMTTTTITE KHKMNVPETM NEVLDMSDDE VRKASAPEKL SDGEYISDGE EGEDAITGDT DKYLGPQDLK ELGDDSLPAE GYVGFSLGAR SASLRSFSSD RSYTLNRSSY ARDSMMIEEL LVPSKEQHLT FTREFDSDSL RHYSWAADTL DNVNLVSSPV HSGFLVSFMV DARGGSMRGS RHHGMRIIIP PRKCTAPTRI TCRLVKRHKL ANPPPMVEGE GLASRLVEMG PAGAQFLGPV IVEIPHFGSM RGKERELIVL RSENGETWKE HQFDSKNEDL AELLNGMDEE LDSPEELGTK RICRIITKDF PQYFAVVSRI KQESNQIGPE GGILSSTTVP LVQASFPEGA LTKRIRVGLQ AQPVPEETVK KILGNKATFS PIVTVEPRRR KFHKPITMTI PVPPPSGEGV SNGYKGDATP NLRLLCSITG GTSPAQWEDI TGTTPLTFIK DCVSFTTNVS ARFWLADCHQ VLETVGLASQ LYRELICVPY MAKFVVFAKT NDPVESSLRC FCMTDDRVDK TLEQQENFEE VARSKDIEVL EGKPIYVDCY GNLAPLTKGG QQLVFNFYSF KENRLPFSIK IRDTSQEPCG RLSFLKEPKT TKGLPQTAVC NLNITLPAHK KETESDQDDA EKADRRQSFA SLALRKRYSY LTEPSMKTVE RSSGTARSLP TTYSHKPFFS TRPYQSWTTA PITVPGPAKS GSLSSSPSNT PSASPLKSIW SVSTPSPIKS TLGASTTSSV KSISDVASPI RSFRTVSSPI KTVVSPSPYN PQVASGTLGR VPTITEATPI KGLAPNSTFS SRTSPVTTAG SLLERSSITM TPPASPKSNI TMYSSSLPFK SIITSATPLI SSPLKSVVSP TKSAADVIST AKATMASSLS SPLKQMSGHA EVALVNGSVS PLKYPSSSAL INGCKATATL QDKISTATNA VSSVVSAASD TVEKALSTTT AMPFSPLRSY VSAAPSAFQS LRTPSASALY TSLGSSIAAT TSSVTSSIIT VPVYSVVNVL PEPALKKLPD SNSFTKSAAA LLSPIKTLTT ETRPQPHFNR TSSPVKSSLF LASSALKPSV PSSLSSSQEI LKDVAEMKED LMRMTAILQT DVPEEKPFQT DLPREGRIDD EEPFKIVEKV KEDLVKVSEI LKKDVCVESK GPPKSPKSDK GHSPEDDWTE FSSEEIREAR QAAASHAPSL PERVHGKANL TRVIDYLTND IGSSSLTNLK YKFEEAKKDG EERQKRILKP AMALQEHKLK MPPASMRPST SEKELCKMAD SFFGADAILE SPDDFSQHDQ DKSPLSDSGF ETRSEKTPSA PQSAESTGPK PLFHEVPIPP VITETRTEVV HVIRSYEPSS GEIPQSQPED PVSPKPSPTF MELEPKPTTS SIKEKVKAFQ MKASSEEEDH SRVLSKGMRV KEETHITTTT RMVYHSPPGG ECASERIEET MSVHDIMKAF QSGRDPSKEL AGLFEHKSAM SPDVAKSAAE TSAQHAEKDS QMKPKLERII EVHIEKGPQS PCERTDIRMA IVADHLGLSW TELARELNFS VDEINQIRVE NPNSLISQSF MLLKKWVTRD GKNATTDALT SVLTKINRID IVTLLEGPIF DYGNISGTRS FADENNVFHD PVDGWQNETP SGSLESPAQA RRLTGGLLDR LDDSSDQARD SITSYLTGEP GKIEANGNHT AEVIPEAKAK PYFPESQNDI GKQSIKENLK PKTHGCGRTE EPVSPLTAYQ KSLEETSKLV IEDAPKPCVP VGMKKMTRTT ADGKARLNLQ EEEGSTRSEP KQGEGYKVKT KKEIRNVEKK TH //