ID   W3XC35_PESFW            Unreviewed;       690 AA.
AC   W3XC35;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=Ion transport domain-containing protein {ECO:0000259|Pfam:PF00520};
GN   ORFNames=PFICI_05486 {ECO:0000313|EMBL:ETS83610.1};
OS   Pestalotiopsis fici (strain W106-1 / CGMCC3.15140).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Xylariomycetidae; Xylariales; Sporocadaceae; Pestalotiopsis.
OX   NCBI_TaxID=1229662 {ECO:0000313|EMBL:ETS83610.1, ECO:0000313|Proteomes:UP000030651};
RN   [1] {ECO:0000313|Proteomes:UP000030651}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=W106-1 / CGMCC3.15140 {ECO:0000313|Proteomes:UP000030651};
RX   PubMed=25623211; DOI=10.1186/s12864-014-1190-9;
RA   Wang X., Zhang X., Liu L., Xiang M., Wang W., Sun X., Che Y., Guo L.,
RA   Liu G., Guo L., Wang C., Yin W.B., Stadler M., Zhang X., Liu X.;
RT   "Genomic and transcriptomic analysis of the endophytic fungus
RT   Pestalotiopsis fici reveals its lifestyle and high potential for synthesis
RT   of natural products.";
RL   BMC Genomics 16:28-28(2015).
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DR   EMBL; KI912111; ETS83610.1; -; Genomic_DNA.
DR   RefSeq; XP_007832258.1; XM_007834067.1.
DR   AlphaFoldDB; W3XC35; -.
DR   STRING; 1229662.W3XC35; -.
DR   GeneID; 19270499; -.
DR   KEGG; pfy:PFICI_05486; -.
DR   eggNOG; ENOG502R4J4; Eukaryota.
DR   HOGENOM; CLU_014699_0_0_1; -.
DR   InParanoid; W3XC35; -.
DR   OMA; GYACEFV; -.
DR   OrthoDB; 2733894at2759; -.
DR   Proteomes; UP000030651; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   PANTHER; PTHR35859:SF5; ION_TRANS DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR35859; NONSELECTIVE CATION CHANNEL PROTEIN; 1.
DR   Pfam; PF00520; Ion_trans; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030651};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        291..309
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        351..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        392..411
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        423..445
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        484..504
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          304..514
FT                   /note="Ion transport"
FT                   /evidence="ECO:0000259|Pfam:PF00520"
FT   REGION          159..186
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          600..655
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        161..186
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        606..645
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   690 AA;  78190 MW;  A74DAD5C20CA667D CRC64;
     MPIRVKARPV SQGDRAPSPY FAPWKPTELP HISYDDVFRD VIKSLSRYIA DCVFLPLTFE
     QLRTTSSGDC LRTLVDHLAE NVLNPAIVNA LLALRWHYST GPDSSGVGDA RANACEIVAW
     RFLTRLSERE AVEFCLYEIP DPKQKSIFLR NAPDLGESNE RTALLPSSSS NEHPGSRPDT
     LRGASQRRTQ LIQSLSKLTM SMQLDSNDEE EDENDPTAPF INLNALEIAA IADAKRFLSQ
     HVVQKIITGI WSGDIIFWDR LSAGSIKKPR FYNPQTADPF CRLRVPRYLK VYEVVFFGLF
     LFLYYAVLIE QNRYAITPRE IMLYVWFAAF CYDEVSEYID AGSIFYSADV WNLFDMIMIA
     IGLVFAILRF IGLYNQDLYM VDIAFDVLSL EALFMVPRIC SILSLSPYWG TLIPCLKEMG
     KDFLKFMVLV VIIYVGFLTT FSLIGRDSYS FNHMAMIVTK IFFGSSYVGF DIMESIDPIF
     GPPLMLIFVT LSSILLMGSL TGMLSNSFSR VISHAREEYL YVYSVYVLEA STSNRLTHFY
     PPFNLLALGI FRPLRLFLPS DNKFRQARIM LLKATHLPIV AVIKAYELIT FRVSPSKDGF
     DSFRGPRQTS RRSPAPPLSS SRRSHISSRH TNHEVISQPS PTRSRQDQDD STDAPTDVEV
     RIAELSSKID RLTALVAMLQ PGAGIETTRT
//