ID W0FJ72_9ENTR Unreviewed; 429 AA. AC W0FJ72; DT 19-MAR-2014, integrated into UniProtKB/TrEMBL. DT 19-MAR-2014, sequence version 1. DT 29-OCT-2014, entry version 7. DE RecName: Full=Arsenical pump membrane protein {ECO:0000256|RuleBase:RU004993}; OS Enterobacter hormaechei subsp. oharae. OG Plasmid unnamed {ECO:0000313|EMBL:AHF23009.1}. OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; OC Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex. OX NCBI_TaxID=301102 {ECO:0000313|EMBL:AHF23009.1}; RN [1] {ECO:0000313|EMBL:AHF23009.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=CCBH 10892 {ECO:0000313|EMBL:AHF23009.1}; RC PLASMID=unnamed {ECO:0000313|EMBL:AHF23009.1}; RX PubMed=24449772; DOI=10.1128/AAC.02804-13; RA Carvalho-Assef A.P., Pereira P.S., Albano R.M., Beriao G.C., RA Tavares C.P., Chagas T.P., Marques E.A., Timm L.N., Da Silva R.C., RA Falci D.R., Asensi M.D.; RT "Detection of NDM-1-, CTX-M-15-, and qnrB4-Producing Enterobacter RT hormaechei Isolates in Brazil."; RL Antimicrob. Agents Chemother. 58:2475-2476(2014). RN [2] {ECO:0000313|EMBL:AHF23009.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=CCBH 10892 {ECO:0000313|EMBL:AHF23009.1}; RC PLASMID=unnamed {ECO:0000313|EMBL:AHF23009.1}; RA Carvalho-Assef A.P.D.A., Pereira P.S., Albano R.M., Beriao G.C., RA Chagas T.P.G., Timm L.N., Da Silva R.C.F., Asensi M.D.; RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Involved in arsenical resistance. Thought to form the CC channel of an arsenite pump. {ECO:0000256|RuleBase:RU004993}. CC -!- SUBCELLULAR LOCATION: Cell membrane CC {ECO:0000256|RuleBase:RU004993}; Multi-pass membrane protein CC {ECO:0000256|RuleBase:RU004993}. CC -!- SIMILARITY: Belongs to the ArsB family. CC {ECO:0000256|RuleBase:RU004993}. CC -!- CAUTION: Lacks conserved residue(s) required for the propagation CC of feature annotation. {ECO:0000256|RuleBase:RU004993}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KF727591; AHF23009.1; -; Genomic_DNA. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0015105; F:arsenite transmembrane transporter activity; IEA:InterPro. DR GO; GO:0015700; P:arsenite transport; IEA:InterPro. DR GO; GO:0046685; P:response to arsenic-containing substance; IEA:UniProtKB-KW. DR InterPro; IPR000802; Arsenical_pump_ArsB. DR Pfam; PF02040; ArsB; 1. DR PRINTS; PR00758; ARSENICPUMP. DR TIGRFAMs; TIGR00935; 2a45; 1. PE 3: Inferred from homology; KW Arsenical resistance {ECO:0000256|RuleBase:RU004993}; KW Membrane {ECO:0000256|RuleBase:RU004993}; KW Plasmid {ECO:0000313|EMBL:AHF23009.1}; KW Transmembrane {ECO:0000256|RuleBase:RU004993}; KW Transmembrane helix {ECO:0000256|RuleBase:RU004993}; KW Transport {ECO:0000256|RuleBase:RU004993}. SQ SEQUENCE 429 AA; 45495 MW; 234413FB0B85809D CRC64; MLLAGAIFVL TIVLVIWQPK GLGIGWSATL GAVLALISGV VHFGDIPVVW NIVWNATATF IAVIIISLLL DESGFFEWAA LHVSRWGNGR GRLLFTYIVL LGAAVAALFA NDGAALILTP IVIAMLLALG FSKGTTLAFV MAAGFIADTA SLPLIVSNLV NIVSADFFGL GFTEYASVMV PVDIAAIIAT LVMLHLFFRK DIPPTYDLAL LKAPAKAIKD LATFRTGWIV LILLLVGFFV LEPLGIPVSA IAAVGAVILF AVAKRGHAIN TGKVLRGAPW QIVIFSLGMY LVVYGLRNAG LTEYLSGVLN VLADKGLWAA TFGTGFLTAF LSSIMNNMPT VLVGALSIDG STATGVIKEA MIFANVIGCD LGPKITPIGS LATLLWLHVL SQKNMTITWG YYFRTGIVMT LPVLFVTLAA LALRLSFTL //