ID W0FJ72_9ENTR Unreviewed; 429 AA. AC W0FJ72; DT 19-MAR-2014, integrated into UniProtKB/TrEMBL. DT 19-MAR-2014, sequence version 1. DT 22-FEB-2023, entry version 29. DE RecName: Full=Arsenical pump membrane protein {ECO:0000256|RuleBase:RU004993}; OS Enterobacter hormaechei subsp. oharae. OG Plasmid unnamed {ECO:0000313|EMBL:AHF23009.1}. OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; OC Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex. OX NCBI_TaxID=301102 {ECO:0000313|EMBL:AHF23009.1}; RN [1] {ECO:0000313|EMBL:AHF23009.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=CCBH 10892 {ECO:0000313|EMBL:AHF23009.1}; RC PLASMID=unnamed {ECO:0000313|EMBL:AHF23009.1}; RX PubMed=24449772; DOI=10.1128/AAC.02804-13; RA Carvalho-Assef A.P., Pereira P.S., Albano R.M., Beriao G.C., Tavares C.P., RA Chagas T.P., Marques E.A., Timm L.N., Da Silva R.C., Falci D.R., RA Asensi M.D.; RT "Detection of NDM-1-, CTX-M-15-, and qnrB4-Producing Enterobacter RT hormaechei Isolates in Brazil."; RL Antimicrob. Agents Chemother. 58:2475-2476(2014). RN [2] {ECO:0000313|EMBL:AHF23009.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=CCBH 10892 {ECO:0000313|EMBL:AHF23009.1}; RC PLASMID=unnamed {ECO:0000313|EMBL:AHF23009.1}; RA Carvalho-Assef A.P.D.A., Pereira P.S., Albano R.M., Beriao G.C., RA Chagas T.P.G., Timm L.N., Da Silva R.C.F., Asensi M.D.; RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Involved in arsenical resistance. Thought to form the channel CC of an arsenite pump. {ECO:0000256|RuleBase:RU004993}. CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU004993}; CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU004993}. Membrane CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein CC {ECO:0000256|ARBA:ARBA00004141}. CC -!- SIMILARITY: Belongs to the ArsB family. CC {ECO:0000256|RuleBase:RU004993}. CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of CC feature annotation. {ECO:0000256|RuleBase:RU004993}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KF727591; AHF23009.1; -; Genomic_DNA. DR RefSeq; WP_000922630.1; NZ_WFLQ01000098.1. DR AlphaFoldDB; W0FJ72; -. DR PATRIC; fig|550.348.peg.2837; -. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0015105; F:arsenite transmembrane transporter activity; IEA:InterPro. DR GO; GO:0046685; P:response to arsenic-containing substance; IEA:UniProtKB-KW. DR CDD; cd01118; ArsB_permease; 1. DR InterPro; IPR000802; Arsenical_pump_ArsB. DR PANTHER; PTHR43302; TRANSPORTER ARSB-RELATED; 1. DR PANTHER; PTHR43302:SF5; TRANSPORTER ARSB-RELATED; 1. DR Pfam; PF02040; ArsB; 1. DR PRINTS; PR00758; ARSENICPUMP. DR TIGRFAMs; TIGR00935; 2a45; 1. PE 3: Inferred from homology; KW Arsenical resistance {ECO:0000256|RuleBase:RU004993}; KW Cell membrane {ECO:0000256|ARBA:ARBA00022475}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU004993}; KW Plasmid {ECO:0000313|EMBL:AHF23009.1}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, KW ECO:0000256|RuleBase:RU004993}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|RuleBase:RU004993}; Transport {ECO:0000256|RuleBase:RU004993}. FT TRANSMEM 51..70 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004993" FT TRANSMEM 91..109 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004993" FT TRANSMEM 115..132 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004993" FT TRANSMEM 139..163 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004993" FT TRANSMEM 175..198 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004993" FT TRANSMEM 222..240 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004993" FT TRANSMEM 246..263 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004993" FT TRANSMEM 275..296 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004993" FT TRANSMEM 316..334 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004993" FT TRANSMEM 401..423 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004993" SQ SEQUENCE 429 AA; 45495 MW; 234413FB0B85809D CRC64; MLLAGAIFVL TIVLVIWQPK GLGIGWSATL GAVLALISGV VHFGDIPVVW NIVWNATATF IAVIIISLLL DESGFFEWAA LHVSRWGNGR GRLLFTYIVL LGAAVAALFA NDGAALILTP IVIAMLLALG FSKGTTLAFV MAAGFIADTA SLPLIVSNLV NIVSADFFGL GFTEYASVMV PVDIAAIIAT LVMLHLFFRK DIPPTYDLAL LKAPAKAIKD LATFRTGWIV LILLLVGFFV LEPLGIPVSA IAAVGAVILF AVAKRGHAIN TGKVLRGAPW QIVIFSLGMY LVVYGLRNAG LTEYLSGVLN VLADKGLWAA TFGTGFLTAF LSSIMNNMPT VLVGALSIDG STATGVIKEA MIFANVIGCD LGPKITPIGS LATLLWLHVL SQKNMTITWG YYFRTGIVMT LPVLFVTLAA LALRLSFTL //