ID V9L051_CALMI Unreviewed; 243 AA. AC V9L051; DT 19-MAR-2014, integrated into UniProtKB/TrEMBL. DT 19-MAR-2014, sequence version 1. DT 19-JAN-2022, entry version 26. DE SubName: Full=Proteolipid protein DM alpha {ECO:0000313|EMBL:AFP04569.1}; GN Name=LOC103190085 {ECO:0000313|Ensembl:ENSCMIP00000042523}; OS Callorhinchus milii (Ghost shark). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes; OC Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus. OX NCBI_TaxID=7868 {ECO:0000313|EMBL:AFP04569.1}; RN [1] {ECO:0000313|Proteomes:UP000314986} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=17185593; DOI=10.1126/science.1130708; RA Venkatesh B., Kirkness E.F., Loh Y.H., Halpern A.L., Lee A.P., Johnson J., RA Dandona N., Viswanathan L.D., Tay A., Venter J.C., Strausberg R.L., RA Brenner S.; RT "Ancient noncoding elements conserved in the human genome."; RL Science 314:1892-1892(2006). RN [2] {ECO:0000313|Proteomes:UP000314986} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=17407382; RA Venkatesh B., Kirkness E.F., Loh Y.H., Halpern A.L., Lee A.P., Johnson J., RA Dandona N., Viswanathan L.D., Tay A., Venter J.C., Strausberg R.L., RA Brenner S.; RT "Survey sequencing and comparative analysis of the elephant shark RT (Callorhinchus milii) genome."; RL PLoS Biol. 5:E101-E101(2007). RN [3] {ECO:0000313|EMBL:AFP04569.1, ECO:0000313|Proteomes:UP000314986} RP NUCLEOTIDE SEQUENCE. RC TISSUE=Testis {ECO:0000313|EMBL:AFP04569.1}; RX PubMed=24402279; DOI=10.1038/nature12826; RG International Elephant Shark Genome Sequencing Consortium; RA Venkatesh B., Lee A.P., Ravi V., Maurya A.K., Lian M.M., Swann J.B., RA Ohta Y., Flajnik M.F., Sutoh Y., Kasahara M., Hoon S., Gangu V., Roy S.W., RA Irimia M., Korzh V., Kondrychyn I., Lim Z.W., Tay B.H., Tohari S., RA Kong K.W., Ho S., Lorente-Galdos B., Quilez J., Marques-Bonet T., RA Raney B.J., Ingham P.W., Tay A., Hillier L.W., Minx P., Boehm T., RA Wilson R.K., Brenner S., Warren W.C.; RT "Elephant shark genome provides unique insights into gnathostome RT evolution."; RL Nature 505:174-179(2014). RN [4] {ECO:0000313|Ensembl:ENSCMIP00000042523} RP IDENTIFICATION. RG Ensembl; RL Submitted (JUL-2019) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. CC -!- SIMILARITY: Belongs to the myelin proteolipid protein family. CC {ECO:0000256|ARBA:ARBA00010595}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JW872051; AFP04569.1; -; mRNA. DR RefSeq; XP_007908926.1; XM_007910735.1. DR STRING; 7868.ENSCMIP00000042523; -. DR Ensembl; ENSCMIT00000043142; ENSCMIP00000042523; ENSCMIG00000017686. DR Ensembl; ENSCMIT00000043147; ENSCMIP00000042528; ENSCMIG00000017686. DR GeneID; 103190085; -. DR KEGG; cmk:103190085; -. DR GeneTree; ENSGT00390000006915; -. DR OrthoDB; 914457at2759; -. DR Proteomes; UP000314986; Unassembled WGS sequence. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR InterPro; IPR001614; Myelin_PLP. DR InterPro; IPR018237; Myelin_PLP_CS. DR PANTHER; PTHR11683; PTHR11683; 1. DR Pfam; PF01275; Myelin_PLP; 1. DR PRINTS; PR00214; MYELINPLP. DR SMART; SM00002; PLP; 1. DR PROSITE; PS00575; MYELIN_PLP_1; 1. DR PROSITE; PS01004; MYELIN_PLP_2; 1. PE 2: Evidence at transcript level; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000314986}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 70..92 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 113..143 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 202..223 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" SQ SEQUENCE 243 AA; 26652 MW; 5966FB843E149277 CRC64; MGCFQCCVKC WGGVPFASLI ATLLCFSGVA LFCGCGHEAL TGTETLIETY FSRDFTDYAL LANVIQIFQY VIYGTASFFF LYGVLLLAEG FYTTSAVKEM YGEFRSTACG KCVSALFILL TYVLGVIWMG VCAASAVPVY VYYNIWATCH MMRENPDNAT DLVCVDARQY GILPWTASPG KVCGLTLAAV CNSSEFNLTY HLFIVTLAGA AATVIALLTY MMATTYNYAV LKFLSREDCC TKF //