ID V9GW27_BOVIN Unreviewed; 2554 AA. AC V9GW27; DT 29-MAY-2024, integrated into UniProtKB/TrEMBL. DT 29-MAY-2024, sequence version 1. DT 29-MAY-2024, entry version 1. DE SubName: Full=USP9X {ECO:0000313|EMBL:JAB84491.1}; GN Name=USP9X {ECO:0000313|VGNC:VGNC:56957}; OS Bos taurus (Bovine). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; OC Bovinae; Bos. OX NCBI_TaxID=9913 {ECO:0000313|EMBL:JAB84491.1}; RN [1] {ECO:0000313|EMBL:JAB84491.1} RP NUCLEOTIDE SEQUENCE. RC TISSUE=Testes {ECO:0000313|EMBL:JAB84491.1}; RA Hughes J.F., Skaletsky H., Bellott D.W., Koutseva N., Cho G., Page D.C.; RT "The DNA sequence of Bos Taurus Y chromosome."; RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; GAPO01000002; JAB84491.1; -; Transcribed_RNA. DR STRING; 9913.ENSBTAP00000047095; -. DR MEROPS; C19.017; -. DR PaxDb; 9913-ENSBTAP00000047095; -. DR CTD; 8239; -. DR VEuPathDB; HostDB:ENSBTAG00000006242; -. DR VGNC; VGNC:56957; USP9X. DR eggNOG; KOG1866; Eukaryota. DR GeneTree; ENSGT00940000155375; -. DR HOGENOM; CLU_000331_1_0_1; -. DR OMA; EYMLRSV; -. DR OrthoDB; 6206at2759; -. DR Reactome; R-BTA-2173795; Downregulation of SMAD2/3:SMAD4 transcriptional activity. DR Reactome; R-BTA-5689880; Ub-specific processing proteases. DR Reactome; R-BTA-8866652; Synthesis of active ubiquitin: roles of E1 and E2 enzymes. DR Reactome; R-BTA-9013420; RHOU GTPase cycle. DR Reactome; R-BTA-9013424; RHOV GTPase cycle. DR Reactome; R-BTA-9033241; Peroxisomal protein import. DR Bgee; ENSBTAG00000006242; Expressed in spiral colon and 111 other cell types or tissues. DR GO; GO:0005813; C:centrosome; IEA:Ensembl. DR GO; GO:0005929; C:cilium; IEA:Ensembl. DR GO; GO:0005829; C:cytosol; IBA:GO_Central. DR GO; GO:0030426; C:growth cone; IEA:Ensembl. DR GO; GO:0005634; C:nucleus; IBA:GO_Central. DR GO; GO:0070410; F:co-SMAD binding; IEA:Ensembl. DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IBA:GO_Central. DR GO; GO:0180017; F:K11-linked deubiquitinase activity; IEA:Ensembl. DR GO; GO:1990380; F:K48-linked deubiquitinase activity; IEA:Ensembl. DR GO; GO:0061578; F:K63-linked deubiquitinase activity; IEA:Ensembl. DR GO; GO:0140313; F:molecular sequestering activity; IEA:Ensembl. DR GO; GO:0048675; P:axon extension; IEA:Ensembl. DR GO; GO:0030509; P:BMP signaling pathway; IEA:Ensembl. DR GO; GO:0016477; P:cell migration; IBA:GO_Central. DR GO; GO:0061824; P:cytosolic ciliogenesis; IEA:Ensembl. DR GO; GO:0006307; P:DNA dealkylation involved in DNA repair; IEA:Ensembl. DR GO; GO:0035520; P:monoubiquitinated protein deubiquitination; IEA:Ensembl. DR GO; GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl. DR GO; GO:0001764; P:neuron migration; IEA:Ensembl. DR GO; GO:1904515; P:positive regulation of TORC2 signaling; IEA:Ensembl. DR GO; GO:0016562; P:protein import into peroxisome matrix, receptor recycling; IEA:Ensembl. DR GO; GO:0050821; P:protein stabilization; IEA:Ensembl. DR GO; GO:0042752; P:regulation of circadian rhythm; IEA:Ensembl. DR GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IEA:Ensembl. DR CDD; cd02659; peptidase_C19C; 1. DR Gene3D; 3.90.70.10; Cysteine proteinases; 1. DR InterPro; IPR016024; ARM-type_fold. DR InterPro; IPR021905; DUF3517. DR InterPro; IPR038765; Papain-like_cys_pep_sf. DR InterPro; IPR001394; Peptidase_C19_UCH. DR InterPro; IPR018200; USP_CS. DR InterPro; IPR028889; USP_dom. DR PANTHER; PTHR24006; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1. DR PANTHER; PTHR24006:SF827; UBIQUITINYL HYDROLASE 1; 1. DR Pfam; PF12030; DUF3517; 1. DR Pfam; PF00443; UCH; 1. DR SUPFAM; SSF48371; ARM repeat; 1. DR SUPFAM; SSF54001; Cysteine proteinases; 1. DR PROSITE; PS00972; USP_1; 1. DR PROSITE; PS00973; USP_2; 1. DR PROSITE; PS50235; USP_3; 1. PE 4: Predicted; SQ SEQUENCE 2554 AA; 290300 MW; 8624673FE5451B99 CRC64; MTATTRGSPV GGNDSQGQAP DGQSQPALQQ NQTSSPDSSN ENSPATPPDE QGQGDAPSQL EDEEPAFPHT DLAKLDDMIN RPRWVVPVLP KGELEVLLEA AIDLSKKGLD VKSEACQRFF RDGLTISFTK ILTDEAVSGW KFEIHRCIIN NTHRLVELCV AKLSQDWFPL LELLSMALNP HCKFHIYNGT RPCESVSSNV QLPEDELFAR SPDPRSPKGW LVDLLNKFGT LNGFQILHDR FINGSALNVQ IIAALIKPFG QCYEFLTLHT VKKYFLPVIE MVPQFLENLT DEELKKEAKN EAKNDALSMI IKSLKNLASR VPGQEETVKN LEIFRLKMIL RLLQISSFNG KMNALNEVNK VISSVSYYTH RHGNPEEEEW LTAERMAEWI QQNNILSIVL RDSLHQPQYV EKLEKILRFV IKEKALTLQD LDNIWAAQAG KHEAIVKNVH DLLAKLAWDF SPEQLDHLFD CFKASWTNAS KKQREKLLEL IRRLAEDDKD GVMAHKVLNL LWNLAHSDDV PVDIMDLALS AHIKILDYSC SQDRDTQKIQ WIDRFIEELR TNDKWVIPAL KQIREICSLF GEAPQNLSQT QRSPHVFYRH DLINQLQHNH ALVTLVAENL ATYMESMRLY ARDHEDYDPQ TVRLGSRYSH VQEVQERLNF LRFLLKDGQL WLCAPQAKQI WKCLAENAVY LCDREACFKW YSKLMGDEPD LDPDINKDFF ESNVLQLDPS LLTENGMKCF ERFFKAVNCR EGKLVAKRRA YMMDDLELIG LDYLWRVVIQ SNDDIASRAI DLLKEIYTNL GPRLQVNQVV IHEDFIQSCF DRLKASYDTL CVLDGDKDSI NCARQEAVRM VRVLTVLREY INECDSDYHE ERTILPMSRA FRGKHLSFIV RFPNQGRQVD DLDVWSHTND TIGSVRRCIL NRIKANVAHT KIELFVGGEL IDPADDRKLI GQLNLKDKSL ITAKLTQISS NMPSSPDSSS DSSTGSPGNH GNHYSDGPNP EVESCLPGVI MSLNPRYISF LWQVADLGSS LNMPPLRDGA RVLMKLMPPD STTIEKLRAI CLDHAKLGDS SLSPSLDSLF FGPSASQVLY LTEVVYALLM PAGALLADDS SDFQFHFLKS GGLPLVLSML TRNNFLPNAD METRRGAYLN ALKIAKLLLT AIGYGHVRAV AEACQPGVEG VNPMASVNQV THDQAVVLQS ALQSIPNPSS ECMLRNVSIR LAQQISDEAS RYMPDICVIR AIQKIIWASG CGALQLVFSP NEEITKIYEK TNAGNEPDLE DEQVCCEAME VMTLCFALIP TALDTLSKEK AWQTFIIDLL LHCHSKTVRQ VAQEQFFLMC TRCCMGHRPL LFFITLLFTV LGSTARERAK HSGDYFTLLR HLLNYAYNSN INIPNAEVLL NNEIDWLKRI RDDVKRTGET GIEETILEGH LGVTKELLAF QTPEKKYHIG CEKGGANLIK ELIDDFIFPA SNVYLQYMRN GELPAEQAIP VCGSPATINA GFELLVALAV GCVRNLKQIV DSLTEMYYIG TAITTCEALT EWEYLPPVGP RPPKGFVGLK NAGATCYMNS VIQQLYMIPS IRNGILAIEG TGSDVDDDLS GDEKQDNESN VDPRDDVFGY PQQFEDKPAL SKTEDRKEYN IGVLRHLQVI FGHLAASRLQ YYVPRGFWKQ FRLWGEPVNL REQHDALEFF NSLVDSLDEA LKALGHPAML SKVLGGSFAD QKICQGCPHR YECEESFTTL NVDIRNHQNL LDSLEQYVKG DLLEGANAYH CEKCNKKVDT VKRLLIKKLP PVLAIQLKRF DYDWERECAI KFNDYFEFPR ELDMEPYTVA GVAKLEGDNV NPESQLIQQN EQSDSETAGS TKYRLVGVLV HSGQASGGHY YSYIIQRNGG DGERNRWYKF DDGDVTECKM DDDEEMKNQC FGGEYMGEVF DHMMKRMSYR RQKRWWNAYI LFYERLDTID QGDELIRYIS ELAITARPHQ IIMPSAIERS VRKQNVQFMH NRMQYSMEYF QFMKKLLTCN GVYLNPPPGQ DHLLPEAEEI TMISIQLAAR FLFTTGFHTK KIVRGSASDW YDALCILLRH SKNVRFWFAH NVLFNVSNRF SEYLLECPSA EVRGAFAKLI VFIAHFSLQD GPCPSPFASP GPSSQAYDNL SLSDHLLRAV LNLLRREVSE HGRHLQQYFN LFVMYANLGV AEKTQLLKLS VPATFMLVSL DEGPGPPIKY QYAELGKLYS VVSQLIRCCN VSSRMQSSIN GNPPLPNPFG DPNLSQPIMP IQQNVADILF VRTSYVKKII EDCSNSEETV KLLRFCCWEN PQFSSTVLSE LLWQVAYSYT YELRPYLDLL LQILLIEDSW QTHRIHNALK GIPDDRDGLF DTIQRSKNHY QKRAYQCIKC MVALFSNCPV AYQILQGNGD LKRKWTWAVE WLGDELERRP YTGNPQYTYN NWSPPVQSNE TSNGYFLERS HSARMTLAKA CELCPEEEPD DQDAPDEHES PPPEDAPLYP HSPGSQYQQN NHVHGQPYTG PAAHHMNNPQ RTGQRAQENY EGSEEVSPPQ TKDQ //