ID V5P5H1_WHEAT Unreviewed; 553 AA. AC V5P5H1; DT 19-FEB-2014, integrated into UniProtKB/TrEMBL. DT 19-FEB-2014, sequence version 1. DT 22-FEB-2023, entry version 27. DE RecName: Full=Protein DETOXIFICATION {ECO:0000256|RuleBase:RU004914}; DE AltName: Full=Multidrug and toxic compound extrusion protein {ECO:0000256|RuleBase:RU004914}; OS Triticum aestivum (Wheat). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade; OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum. OX NCBI_TaxID=4565 {ECO:0000313|EMBL:AHA98253.1}; RN [1] {ECO:0000313|EMBL:AHA98253.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=24588850; RA Garcia-Oliveira A.L., Martins-Lopes P., Tolra R., Poschenrieder C., RA Tarquis M., Guedes-Pinto H., Benito C.; RT "Molecular characterization of the citrate transporter gene TaMATE1 and RT expression analysis of upstream genes involved in organic acid transport RT under Al stress in bread wheat (Triticum aestivum)."; RL Physiol. Plantarum 0:0-0(2014). CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. CC -!- SIMILARITY: Belongs to the multi antimicrobial extrusion (MATE) (TC CC 2.A.66.1) family. {ECO:0000256|ARBA:ARBA00010199, CC ECO:0000256|RuleBase:RU004914}. CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of CC feature annotation. {ECO:0000256|RuleBase:RU004914}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KF527240; AHA98253.1; -; mRNA. DR AlphaFoldDB; V5P5H1; -. DR ExpressionAtlas; V5P5H1; baseline and differential. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell. DR GO; GO:0015297; F:antiporter activity; IEA:InterPro. DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro. DR CDD; cd13136; MATE_DinF_like; 1. DR InterPro; IPR044644; DinF-like. DR InterPro; IPR002528; MATE_fam. DR PANTHER; PTHR42893:SF4; PROTEIN DETOXIFICATION 42; 1. DR PANTHER; PTHR42893; PROTEIN DETOXIFICATION 44, CHLOROPLASTIC-RELATED; 1. DR Pfam; PF01554; MatE; 2. DR TIGRFAMs; TIGR00797; matE; 1. PE 2: Evidence at transcript level; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU004914}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, KW ECO:0000256|RuleBase:RU004914}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|RuleBase:RU004914}. FT TRANSMEM 208..234 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004914" FT TRANSMEM 246..266 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004914" FT TRANSMEM 346..368 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004914" FT TRANSMEM 388..408 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004914" FT TRANSMEM 429..449 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004914" FT TRANSMEM 461..482 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004914" FT TRANSMEM 494..513 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004914" FT TRANSMEM 519..536 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004914" SQ SEQUENCE 553 AA; 58260 MW; B5680245E23C1941 CRC64; MEEGAAASMT VGEKRVAVDV PTDAAAAANG HGPEEKAAED VPAPSALSGW PRTTGMYLFV MNIRFVFKLD ELGSEVLRIA VPASLALAAD PLASLVDTAF IGRLGSVEIA AVGVSIAIFN QVSKVCIYPL VSVTTSFVAE EDAIISKYLE ENNSKDLEKA AHVHSDACNV PASGGDTPVC ANSCIPTECA DLSNQGCKRR YIPSVTSALI VGSFLGLVQA VFLIFSAKVV LGIMGVKHDS PMLEPAVRYL TIRSLGAPAV LLSLAMQGVF RGFKDTKTPL YATVVGDATN IILDPILMFV CHMGVTGAAV AHVISQYLIT MILICRLVQQ VDVIPPSLKS LKFGRFLGCG FLLLARVVAV TFCVTLASSL AARDGPTIMA AFQICCQLWL ATSLLADGLA VAGQAVLASA FAKNDTKKVI AATSRVRQVS IVLGMGLTVV LGLFMKFGAG VFTKDAAVID VIHKGIPFVA GTQTINALAF VFDGINFGAQ DYTYSAYSMV GVASISIPCL VYLSAHKGFI GIWVALTIYM SLRTVASTWR MGAASGPWVF LRK //