ID V4KBR8_EUTSA Unreviewed; 622 AA. AC V4KBR8; DT 22-JAN-2014, integrated into UniProtKB/TrEMBL. DT 22-JAN-2014, sequence version 1. DT 02-JUN-2021, entry version 27. DE RecName: Full=DNA polymerase alpha subunit B {ECO:0000256|ARBA:ARBA00018596, ECO:0000256|PIRNR:PIRNR018300}; GN ORFNames=EUTSA_v10018287mg {ECO:0000313|EMBL:ESQ28529.1}; OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema. OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ28529.1, ECO:0000313|Proteomes:UP000030689}; RN [1] {ECO:0000313|EMBL:ESQ28529.1, ECO:0000313|Proteomes:UP000030689} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=23518688; DOI=10.3389/fpls.2013.00046; RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J., RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A., RA Mitchell-Olds T., Schumaker K.S., Wang X.; RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum."; RL Front. Plant Sci. 4:46-46(2013). CC -!- FUNCTION: Accessory subunit of the DNA polymerase alpha complex (also CC known as the alpha DNA polymerase-primase complex) which plays an CC essential role in the initiation of DNA synthesis. CC {ECO:0000256|PIRNR:PIRNR018300}. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123, CC ECO:0000256|PIRNR:PIRNR018300}. CC -!- SIMILARITY: Belongs to the DNA polymerase alpha subunit B family. CC {ECO:0000256|ARBA:ARBA00007299, ECO:0000256|PIRNR:PIRNR018300}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KI517953; ESQ28529.1; -; Genomic_DNA. DR RefSeq; XP_006391243.1; XM_006391181.1. DR SMR; V4KBR8; -. DR STRING; 72664.XP_006391243.1; -. DR EnsemblPlants; ESQ28529; ESQ28529; EUTSA_v10018287mg. DR GeneID; 18008418; -. DR Gramene; ESQ28529; ESQ28529; EUTSA_v10018287mg. DR KEGG; eus:EUTSA_v10018287mg; -. DR eggNOG; KOG1625; Eukaryota. DR OrthoDB; 513979at2759; -. DR Proteomes; UP000030689; Unassembled WGS sequence. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0003677; F:DNA binding; IEA:InterPro. DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR007185; DNA_pol_a/d/e_bsu. DR InterPro; IPR016722; DNA_pol_alpha_bsu. DR PANTHER; PTHR23061; PTHR23061; 1. DR Pfam; PF04042; DNA_pol_E_B; 1. DR PIRSF; PIRSF018300; DNA_pol_alph_2; 1. PE 3: Inferred from homology; KW DNA replication {ECO:0000256|ARBA:ARBA00022705, KW ECO:0000256|PIRNR:PIRNR018300}; Nucleus {ECO:0000256|PIRNR:PIRNR018300}; KW Reference proteome {ECO:0000313|Proteomes:UP000030689}. FT DOMAIN 363..573 FT /note="DNA_pol_E_B" FT /evidence="ECO:0000259|Pfam:PF04042" FT REGION 107..130 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 107..125 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 622 AA; 69301 MW; 36DBA3369D316195 CRC64; MATDEEIKRE FNRSGFALVE EEEILERCVT LCINYSLKPS ELVSSWELYH LNRQIIDQTV KKDEMDGFLL HLQNQQRESI MKEEAGLHIY SNRDVDMILD GIPEDTTEET VTTPTNNSQR LHPDPFDSIN RSKDYGYSTG KSAGHVTPFA RRIDKFVVKF NIGNNVEAQA ENGHNNDVES SEDDMIIQRV QTSHRCSLKV NGSGPEAGCR FMYDRTEDRF NALENRIIRH ADAFAASGLY DEQVDPAVAS QRSIFAVGMI CCDGEGHLND KSILLQSSAE RTSGQRVPLD LNRLNQFSIF PGQIVGIEGQ NPSGHYFTAS KLVDSVPLTV TTDVDLPPAK KQNLDQEVLP LADESREKTD VSFIVASGPF TTTDNLLFEP LNELLAYAKR KPPQLLVLLG PFVDSEHPEI KKGAVDATFN EIFHVEVLRK LQDYVEFMGS EVRVVLVPSI RDANHDFIFP QPPFNIHIPD LEHQMTSLSN PGTFEANQVK VGCCTVDVLK HLSGEEMSKN PSGATTDRMS RLASHLLRQR SFYPLYPPPE SLPYDSTLAP KALQISSIPD ILLLPSDMRY FVKVLSLGEG EDAVKCVCVN PGRLAKGEGA GTFVELSYKG GPESMHASII SI //