ID   U5ZAB9_HUMAN            Unreviewed;       261 AA.
AC   U5ZAB9;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   19-MAR-2014, entry version 3.
DE   RecName: Full=Cytochrome c oxidase subunit 3;
GN   Name=COX3;
OS   Homo sapiens (Human).
OG   Mitochondrion.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RA   Duggan A.T., Whitten M., Wiebe V., Crawford M., Butthof A.,
RA   Spitsyn V., Makarov S., Novgorodov I., Osakovsky V., Pakendorf B.;
RT   "Investigating the Prehistory of Tungusic Peoples of Siberia and the
RT   Amur-Ussuri Region with Complete mtDNA Genome Sequences and Y-
RT   chromosomal Markers.";
RL   PLoS ONE 8:e83570-e83570(2013).
CC   -!- FUNCTION: Subunits I, II and III form the functional core of the
CC       enzyme complex (By similarity).
CC   -!- SIMILARITY: Belongs to the cytochrome c oxidase subunit 3 family.
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DR   EMBL; KF148554; AHA02043.1; -; Genomic_DNA.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
DR   GO; GO:0019646; P:aerobic electron transport chain; IEA:InterPro.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; IEA:GOC.
DR   Gene3D; 1.20.120.80; -; 1.
DR   InterPro; IPR024791; Cyt_c/ubiquinol_Oxase_su3.
DR   InterPro; IPR000298; Cyt_c_oxidase_su3.
DR   InterPro; IPR013833; Cyt_c_oxidase_su3_a-hlx.
DR   PANTHER; PTHR11403; PTHR11403; 1.
DR   Pfam; PF00510; COX3; 1.
DR   SUPFAM; SSF81452; SSF81452; 1.
DR   PROSITE; PS50253; COX3; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Transmembrane.
SQ   SEQUENCE   261 AA;  29921 MW;  A0438335DE21D914 CRC64;
     MTHQSHAYHM VKPSPWPLAG ALSALLMTSG LAMWFHFHSM TLLMLGLLTN TLTMYQWWRD
     VTRESTYQGH HTPPVQKGLR YGMILFITSE VFFFAGFFWA FYHSSLAPTP QLGGHWPPTG
     ITPLNPLEVP LLNTSVLLAS GVSITWAHHS LMENNRNQMI QALLITILLG LYFTLLQASE
     YFESPFTISD GIYGSTFFVA TGFHGLHVII GSTFLTICFI RQLMFHFTSK HHFGFEAAAW
     YWHFVDVVWL FLYVSIYWWG S
//