ID U5RTP5_9CLOT Unreviewed; 284 AA. AC U5RTP5; DT 22-JAN-2014, integrated into UniProtKB/TrEMBL. DT 22-JAN-2014, sequence version 1. DT 16-MAR-2016, entry version 18. DE RecName: Full=Energy-coupling factor transporter ATP-binding protein EcfA {ECO:0000256|HAMAP-Rule:MF_01710}; DE Short=ECF transporter A component EcfA {ECO:0000256|HAMAP-Rule:MF_01710}; DE EC=3.6.3.- {ECO:0000256|HAMAP-Rule:MF_01710}; GN Name=ecfA {ECO:0000256|HAMAP-Rule:MF_01710, GN ECO:0000313|EMBL:ALU36298.1}; GN ORFNames=CAETHG_1917 {ECO:0000313|EMBL:AGY76136.1}, CLAU_1869 GN {ECO:0000313|EMBL:ALU36298.1}; OS Clostridium autoethanogenum DSM 10061. OC Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; OC Clostridium. OX NCBI_TaxID=1341692 {ECO:0000313|EMBL:AGY76136.1, ECO:0000313|Proteomes:UP000017590}; RN [1] {ECO:0000313|EMBL:AGY76136.1, ECO:0000313|Proteomes:UP000017590} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=DSM 10061 {ECO:0000313|EMBL:AGY76136.1}; RX PubMed=24655715; DOI=10.1186/1754-6834-7-40; RA Brown S.D., Nagaraju S., Utturkar S., De Tissera S., Segovia S., RA Mitchell W., Land M.L., Dassanayake A., Kopke M.; RT "Comparison of single-molecule sequencing and hybrid approaches for RT finishing the genome of Clostridium autoethanogenum and analysis of RT CRISPR systems in industrial relevant Clostridia."; RL Biotechnol. Biofuels 7:40-40(2014). RN [2] {ECO:0000313|EMBL:ALU36298.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=DSM 10061 {ECO:0000313|EMBL:ALU36298.1}; RX PubMed=26692227; DOI=10.1186/s12864-015-2287-5; RA Humphreys C.M., McLean S., Schatschneider S., Millat T., Henstra A.M., RA Annan F.J., Breitkopf R., Pander B., Piatek P., Rowe P., RA Wichlacz A.T., Woods C., Norman R., Blom J., Goesman A., Hodgman C., RA Barrett D., Thomas N.R., Winzer K., Minton N.P.; RT "Whole genome sequence and manual annotation of Clostridium RT autoethanogenum, an industrially relevant bacterium."; RL BMC Genomics 16:1085-1085(2015). CC -!- FUNCTION: ATP-binding (A) component of a common energy-coupling CC factor (ECF) ABC-transporter complex. Unlike classic ABC CC transporters this ECF transporter provides the energy necessary to CC transport a number of different substrates. {ECO:0000256|HAMAP- CC Rule:MF_01710}. CC -!- SUBUNIT: Forms a stable energy-coupling factor (ECF) transporter CC complex composed of 2 membrane-embedded substrate-binding proteins CC (S component), 2 ATP-binding proteins (A component) and 2 CC transmembrane proteins (T component). {ECO:0000256|HAMAP- CC Rule:MF_01710}. CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP- CC Rule:MF_01710, ECO:0000256|SAAS:SAAS00210609}; Peripheral membrane CC protein {ECO:0000256|HAMAP-Rule:MF_01710, CC ECO:0000256|SAAS:SAAS00210609}. CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Energy- CC coupling factor EcfA family. {ECO:0000256|HAMAP-Rule:MF_01710}. CC -!- SIMILARITY: Contains 1 ABC transporter domain. {ECO:0000256|HAMAP- CC Rule:MF_01710}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP006763; AGY76136.1; -; Genomic_DNA. DR EMBL; CP012395; ALU36298.1; -; Genomic_DNA. DR RefSeq; WP_013240663.1; NZ_CP012395.1. DR EnsemblBacteria; AGY76136; AGY76136; CAETHG_1917. DR KEGG; cah:CAETHG_1917; -. DR KO; K16787; -. DR Proteomes; UP000017590; Chromosome. DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:UniProtKB-HAMAP. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP. DR GO; GO:0016887; F:ATPase activity; IEA:InterPro. DR GO; GO:0006824; P:cobalt ion transport; IEA:InterPro. DR Gene3D; 3.40.50.300; -; 1. DR InterPro; IPR003593; AAA+_ATPase. DR InterPro; IPR003439; ABC_transporter-like. DR InterPro; IPR017871; ABC_transporter_CS. DR InterPro; IPR015856; ABC_transpr_CbiO/EcfA_su. DR InterPro; IPR005876; Co_trans_ATP-bd. DR InterPro; IPR030946; EcfA2. DR InterPro; IPR027417; P-loop_NTPase. DR Pfam; PF00005; ABC_tran; 1. DR SMART; SM00382; AAA; 1. DR SUPFAM; SSF52540; SSF52540; 1. DR TIGRFAMs; TIGR01166; cbiO; 1. DR TIGRFAMs; TIGR04521; ECF_ATPase_2; 1. DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1. DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1. DR PROSITE; PS51246; CBIO; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000256|HAMAP-Rule:MF_01710, KW ECO:0000256|RuleBase:RU363012, ECO:0000256|SAAS:SAAS00436461}; KW Cell membrane {ECO:0000256|HAMAP-Rule:MF_01710, KW ECO:0000256|SAAS:SAAS00436478}; KW Complete proteome {ECO:0000313|Proteomes:UP000017590}; KW Hydrolase {ECO:0000256|HAMAP-Rule:MF_01710, KW ECO:0000256|SAAS:SAAS00436468, ECO:0000313|EMBL:AGY76136.1}; KW Membrane {ECO:0000256|HAMAP-Rule:MF_01710, KW ECO:0000256|SAAS:SAAS00436517}; KW Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01710, KW ECO:0000256|RuleBase:RU363012, ECO:0000256|SAAS:SAAS00436457}; KW Reference proteome {ECO:0000313|Proteomes:UP000017590}; KW Transport {ECO:0000256|HAMAP-Rule:MF_01710, KW ECO:0000256|SAAS:SAAS00436501}. FT DOMAIN 2 227 CBIO. {ECO:0000259|PROSITE:PS51246}. FT DOMAIN 3 245 ABC transporter. {ECO:0000259|PROSITE: FT PS50893}. FT NP_BIND 40 47 ATP. {ECO:0000256|HAMAP-Rule:MF_01710}. SQ SEQUENCE 284 AA; 31839 MW; 01AF91074667E3E5 CRC64; MPIKIENLTH IYMKGSPFEK KALDDINIEI EDGEFVALIG HTGSGKSTLI QHINGLLKPS SGKIIVDGVD ITDKKINLNF IRKKVGLVFQ YPEYQLFEET IEKDIAFGPK NLGLSDDDIN KRVKRAMNMV GLKYEDYKDK SPFELSGGQK RRVAIAGVVA MEPKVLILDE PTAGLDPKGR DDIFSEIKNL HREYNMTIIF VSHSMEDVAK LAGRIIVMHQ GKCILDGPPE KVFNEVDTLE SVGLAVPQVT YMVKKLREKG INISKDVFTV KQAKEEILKI LNKS //