ID U4PZH0_9INFA Unreviewed; 498 AA. AC U4PZH0; DT 11-DEC-2013, integrated into UniProtKB/TrEMBL. DT 11-DEC-2013, sequence version 1. DT 05-JUN-2019, entry version 28. DE RecName: Full=Nucleoprotein {ECO:0000256|RuleBase:RU361251, ECO:0000256|SAAS:SAAS00966157}; DE Flags: Fragment; GN Name=NP {ECO:0000256|RuleBase:RU361251, ECO:0000313|EMBL:CDH98257.1}; OS Influenza A virus (A/PERTH/201/2002(H3N2)). OC Viruses; Riboviria; Negarnaviricota; Polyploviricotina; OC Insthoviricetes; Articulavirales; Orthomyxoviridae; OC Alphainfluenzavirus. OX NCBI_TaxID=514753 {ECO:0000313|EMBL:CDH98257.1}; RN [1] {ECO:0000313|EMBL:CDH98257.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=A/PERTH/201/2002 {ECO:0000313|EMBL:CDH98257.1}; RX DOI=10.1038/ncomms3663; RA Valkenburg S.A., Quinones-Parra S., Gras S., Komadina N., McVernon J., RA Wang Z., Halim H., Iannello P., Cole C., Laurie K., Kelso A., RA Rossjohn J., Doherty P.C., Turner S.J., Kedzierska K.; RT "Acute emergence and reversion of influenza A virus quasispecies RT within CD8. T cell antigenic peptides."; RL Nat. Commun. 4:2633-2633(2013). CC -!- FUNCTION: Encapsidates the negative strand viral RNA, protecting CC it from nucleases. The encapsidated genomic RNA is termed the CC ribonucleoprotein (RNP) and serves as template for transcription CC and replication. {ECO:0000256|RuleBase:RU361251}. CC -!- SUBUNIT: Homomultimerizes to form the nucleocapsid. CC {ECO:0000256|RuleBase:RU361251}. CC -!- SUBCELLULAR LOCATION: Host nucleus {ECO:0000256|RuleBase:RU361251, CC ECO:0000256|SAAS:SAAS00966152}. Virion CC {ECO:0000256|RuleBase:RU361251}. CC -!- SIMILARITY: Belongs to the influenza viruses nucleoprotein family. CC {ECO:0000256|RuleBase:RU361251, ECO:0000256|SAAS:SAAS00966161}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; HG455027; CDH98257.1; -; Viral_cRNA. DR GO; GO:0019029; C:helical viral capsid; IEA:UniProtKB-KW. DR GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0019013; C:viral nucleocapsid; IEA:UniProtKB-UniRule. DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW. DR GO; GO:0005198; F:structural molecule activity; IEA:UniProtKB-UniRule. DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW. DR GO; GO:0075732; P:viral penetration into host nucleus; IEA:UniProtKB-KW. DR HAMAP; MF_04070; INFV_NCAP; 1. DR InterPro; IPR002141; Flu_NP. DR Pfam; PF00506; Flu_NP; 1. PE 3: Inferred from homology; KW Capsid protein {ECO:0000256|RuleBase:RU361251, KW ECO:0000256|SAAS:SAAS00966151}; KW Helical capsid protein {ECO:0000256|SAAS:SAAS00966174}; KW Host nucleus {ECO:0000256|RuleBase:RU361251, KW ECO:0000256|SAAS:SAAS00966147}; KW Host-virus interaction {ECO:0000256|SAAS:SAAS00966156}; KW Ribonucleoprotein {ECO:0000256|SAAS:SAAS00966134}; KW RNA-binding {ECO:0000256|SAAS:SAAS00966163}; KW Viral nucleoprotein {ECO:0000256|RuleBase:RU361251, KW ECO:0000313|EMBL:CDH98257.1}; KW Viral penetration into host nucleus {ECO:0000256|SAAS:SAAS00966166}; KW Virion {ECO:0000256|RuleBase:RU361251, ECO:0000256|SAAS:SAAS00966164}; KW Virus entry into host cell {ECO:0000256|SAAS:SAAS00966165}. FT REGION 1 22 Disordered. {ECO:0000256|MobiDB-lite: FT U4PZH0}. FT NON_TER 1 1 {ECO:0000313|EMBL:CDH98257.1}. FT NON_TER 498 498 {ECO:0000313|EMBL:CDH98257.1}. SQ SEQUENCE 498 AA; 56005 MW; 7AC03B23716BDEC9 CRC64; MASQGTKRSY EQMETDGDRQ NATEIRASVG KMIDGIGRFY IQMCTELKLS DYEGRLIQNS LTIEKMVLSA FDERRNRYLE EHPSAGKDPK KTGGPIYKRV DGRWMRELVL YDKEEIRRIW RQANNGEDAT AGLTHMMIWH SNLNDTTYQR TRALVRTGMD PRMCSLMQGS TLPRRSGAAG AAVKGIGTMV MELIRMVKRG INDRNFWRGD NGRKTRSAYE RMCNILKGKF QTAAQRAMVD QVRESRNPGN AEIEDLIFLA RSALILRGSV AHKSCLPACV YGPAVSSGYD FEKEGYSLVG IDPFKLLQNS QVYSLIRPNE NPAHKSQLVW MACHSAAFED LRLLSFIRGT KVSPRGKLST RGVQIASNEN MDNMGSSTLE LRSGYWAIRT RSGGNTNQQR ASAGQISVQP TFSVQRNLPF EKSTVMAAFT GNTEGRTSDM RAEIIRMMEG AKPEEVSFRG RGVFELSDEK ATNPIVPSFD MNNEGSYFFG DNAEEYDN //