ID U3LTB8_9STRA Unreviewed; 195 AA. AC U3LTB8; DT 11-DEC-2013, integrated into UniProtKB/TrEMBL. DT 11-DEC-2013, sequence version 1. DT 16-APR-2014, entry version 5. DE RecName: Full=Cytochrome c oxidase subunit 2; DE Flags: Fragment; GN Name=COX2; OS Pythium nagaii. OG Mitochondrion. OC Eukaryota; Stramenopiles; Oomycetes; Pythiales; Pythiaceae; Pythium. OX NCBI_TaxID=289625; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=P16712; RX PubMed=23709523; DOI=10.3852/12-322; RA Bahramisharif A., Lamprecht S.C., Spies C.F., Botha W.J., McLeod A.; RT "Pythium cederbergense sp. nov. and related taxa from Pythium clade G RT associated with the South African indigenous plant Aspalathus linearis RT (rooibos)."; RL Mycologia 105:1174-1189(2013). CC -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory CC chain that catalyzes the reduction of oxygen to water. Subunits 1- CC 3 form the functional core of the enzyme complex. Subunit 2 CC transfers the electrons from cytochrome c via its binuclear copper CC A center to the bimetallic center of the catalytic subunit 1 (By CC similarity). CC -!- COFACTOR: Copper A (By similarity). CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass CC membrane protein (By similarity). CC -!- SIMILARITY: Belongs to the cytochrome c oxidase subunit 2 family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JX397984; AGK25033.1; -; Genomic_DNA. DR GO; GO:0016021; C:integral component of membrane; IEA:InterPro. DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW. DR GO; GO:0005507; F:copper ion binding; IEA:InterPro. DR GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro. DR GO; GO:0022900; P:electron transport chain; IEA:InterPro. DR Gene3D; 1.10.287.90; -; 1. DR Gene3D; 2.60.40.420; -; 1. DR InterPro; IPR008972; Cupredoxin. DR InterPro; IPR002429; Cyt_c_oxidase_su2_C. DR InterPro; IPR011759; Cyt_c_oxidase_su2_TM_dom. DR Pfam; PF00116; COX2; 1. DR Pfam; PF02790; COX2_TM; 1. DR SUPFAM; SSF49503; SSF49503; 1. DR SUPFAM; SSF81464; SSF81464; 1. DR PROSITE; PS50857; COX2_CUA; 1. DR PROSITE; PS50999; COX2_TM; 1. PE 3: Inferred from homology; KW Copper; Electron transport; Membrane; Metal-binding; Mitochondrion; KW Mitochondrion inner membrane; Respiratory chain; Transmembrane; KW Transmembrane helix; Transport. FT NON_TER 1 1 FT NON_TER 195 195 SQ SEQUENCE 195 AA; 22258 MW; B9E9F027B274F643 CRC64; PATPVMEGII NFHHDLMFFL IVVTIFVCWM LFRVITLFDE KKNKIPSTVV HGATIEIIWT SVPALILLTV AVPSFALLYS MDEVIDPIIT LKVIGSQWYW SYEYSDNLEF SDEPLIFDSY MVQENDLEIG QFRLLEVDNR VVVPTNSHIR VLITASDVLH SWAIPSLGIK LDACPGRLNQ TSMFIKREGV FYGQC //