ID T2G076_ECOLX Unreviewed; 831 AA. AC T2G076; DT 13-NOV-2013, integrated into UniProtKB/TrEMBL. DT 13-NOV-2013, sequence version 1. DT 01-OCT-2014, entry version 10. DE SubName: Full=PTS fructose transporter subunit IIA {ECO:0000313|EMBL:AGW09584.1}; GN ORFNames=LY180_12290 {ECO:0000313|EMBL:AGW09584.1}; OS Escherichia coli LY180. OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; OC Enterobacteriaceae; Escherichia. OX NCBI_TaxID=1335916 {ECO:0000313|EMBL:AGW09584.1, ECO:0000313|Proteomes:UP000016700}; RN [1] {ECO:0000313|EMBL:AGW09584.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=LY180 {ECO:0000313|EMBL:AGW09584.1}; RA Geddes R.D., Wang X., Yomano L.P., Miller E.N., Zheng H., RA Shanmugam K.T., Ingram L.O.; RT "Polyamines and Polyamine Transporters Increase Furfural Tolerance of RT Ethanologenic Escherichia coli strain LY180."; RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: Phosphoenolpyruvate + protein L-histidine = CC pyruvate + protein N(pi)-phospho-L-histidine. CC {ECO:0000256|SAAS:SAAS00070195}. CC -!- SIMILARITY: Contains PTS EIIA type-2 domain. CC {ECO:0000256|SAAS:SAAS00043736}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP006584; AGW09584.1; -; Genomic_DNA. DR RefSeq; WP_000955931.1; NC_022364.1. DR RefSeq; YP_008565545.1; NC_022364.1. DR EnsemblBacteria; AGW09584; AGW09584; LY180_12290. DR GeneID; 16980128; -. DR KEGG; ecol:LY180_12290; -. DR KO; K08483; -. DR KO; K11189; -. DR KO; K11201; -. DR GO; GO:0016021; C:integral component of membrane; IEA:InterPro. DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW. DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro. DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW. DR Gene3D; 1.10.274.10; -; 1. DR Gene3D; 3.20.20.60; -; 1. DR Gene3D; 3.30.1340.10; -; 1. DR Gene3D; 3.40.930.10; -; 1. DR Gene3D; 3.50.30.10; -; 1. DR InterPro; IPR000032; HPr_prot-like. DR InterPro; IPR008279; PEP-util_enz_mobile_dom. DR InterPro; IPR000121; PEP_util_C. DR InterPro; IPR023151; PEP_util_CS. DR InterPro; IPR006318; PEP_util_enz. DR InterPro; IPR016152; PTrfase/Anion_transptr. DR InterPro; IPR002178; PTS_EIIA_type-2_dom. DR InterPro; IPR008731; PTS_EIN. DR InterPro; IPR004715; PTS_IIA_fruc. DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom. DR Pfam; PF05524; PEP-utilisers_N; 1. DR Pfam; PF00391; PEP-utilizers; 1. DR Pfam; PF02896; PEP-utilizers_C; 1. DR Pfam; PF00381; PTS-HPr; 1. DR Pfam; PF00359; PTS_EIIA_2; 1. DR PRINTS; PR01736; PHPHTRNFRASE. DR SUPFAM; SSF47831; SSF47831; 1. DR SUPFAM; SSF51621; SSF51621; 1. DR SUPFAM; SSF52009; SSF52009; 1. DR SUPFAM; SSF55594; SSF55594; 1. DR SUPFAM; SSF55804; SSF55804; 1. DR TIGRFAMs; TIGR00848; fruA; 1. DR TIGRFAMs; TIGR01417; PTS_I_fam; 1. DR PROSITE; PS00742; PEP_ENZYMES_2; 1. DR PROSITE; PS51094; PTS_EIIA_TYPE_2; 1. DR PROSITE; PS51350; PTS_HPR_DOM; 1. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000016700}; KW Kinase {ECO:0000256|SAAS:SAAS00070170}; KW Phosphotransferase system {ECO:0000256|SAAS:SAAS00070264}; KW Transferase {ECO:0000256|SAAS:SAAS00070273}. SQ SEQUENCE 831 AA; 92174 MW; 966560D0EBA6F1D4 CRC64; MLTIQFLCPL PNGLHARPAW ELKEQCSQWQ SEVTFINHRQ NAKADAKSSL ALIGTGTLFN DSCSLNISGS DEEQARRVLE EYIQVRFIDS DSVQPTQAEL TAHPLPRSLS RLNPDLLYGN VLASGVGVGT LTLLQSDSLD SYRAIPASAQ DSTRLEHSLA TLAEQLNQQL RERDGESKTI LSAHLSLIQD DEFAGNIRRL MTEQHQGLGA AIISNMEQVC AKLSASASDY LRERVSDIRD ISEQLLHITW PELKPRNNLV LEKPTILVAE DLTPSQFLSL DLKNLAGMIL EKTGRTSHTL ILARASAIPV LSGLPLDAIA RYAGQPAVLD AQCGVLAINP NDAVSGYYQV AQTLADKRQK QQAQAAAQLA YSRDNKRIDI AANIGTALEA PGAFANGAEG VGLFRTEMLY MDRDSAPDEQ EQFEAYQQVL LAAGDKPIIF RTMDIGGDKS IPYLNIPQEE NPFLGYRAVR IYPEFAALFR TQLRAILRAA SFGNAQLMIP MVHSLDQILW VKGEIQKAIV ELKRDGLRHA ETITLGIMVE VPSVCYIIDH FCDEVDFFSI GSNDMTQYLY AVDRNNPRVS PLYNPITPSF LRMLQQIVTT AHQRGKWVGI CGELGGESRY LPLLLGLGLD ELSMSSPRIP AVKSQLRQLD SEACRELARQ ACECRSAQEI EALLTAFTPE EDVRPLLALE NIFVDQDFSN KEQAIQFLCG NLGVNGRTEH PFELEEDVWQ REEIVTTGVG FGVAIPHTKS QWIRHSSISI ARLAKPIDWQ SEMGEVELVI MLTLGANEGM NHVKVFSQLA RKLVNKNFRQ SLFAAQDAQS ILTLLETELT F //