ID S9VQE7_SCHCR Unreviewed; 736 AA. AC S9VQE7; DT 16-OCT-2013, integrated into UniProtKB/TrEMBL. DT 16-OCT-2013, sequence version 1. DT 24-JAN-2024, entry version 31. DE SubName: Full=Polyphosphate synthetase {ECO:0000313|EMBL:EPY50188.1}; GN ORFNames=SPOG_00949 {ECO:0000313|EMBL:EPY50188.1}; OS Schizosaccharomyces cryophilus (strain OY26 / ATCC MYA-4695 / CBS 11777 / OS NBRC 106824 / NRRL Y48691) (Fission yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; OC Schizosaccharomyces. OX NCBI_TaxID=653667 {ECO:0000313|EMBL:EPY50188.1, ECO:0000313|Proteomes:UP000015464}; RN [1] {ECO:0000313|EMBL:EPY50188.1, ECO:0000313|Proteomes:UP000015464} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=OY26 / ATCC MYA-4695 / CBS 11777 / NBRC 106824 / NRRL Y48691 RC {ECO:0000313|Proteomes:UP000015464}; RX PubMed=21511999; DOI=10.1126/science.1203357; RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N., RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y., RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H., RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G., RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A., RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P., RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R., RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J., RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W., RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.; RT "Comparative functional genomics of the fission yeasts."; RL Science 332:930-936(2011). CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Vacuole membrane CC {ECO:0000256|ARBA:ARBA00004128}; Multi-pass membrane protein CC {ECO:0000256|ARBA:ARBA00004128}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KE546993; EPY50188.1; -; Genomic_DNA. DR RefSeq; XP_013024674.1; XM_013169220.1. DR AlphaFoldDB; S9VQE7; -. DR STRING; 653667.S9VQE7; -. DR EnsemblFungi; EPY50188; EPY50188; SPOG_00949. DR GeneID; 25035280; -. DR eggNOG; KOG1161; Eukaryota. DR eggNOG; KOG4580; Eukaryota. DR HOGENOM; CLU_009308_2_0_1; -. DR OMA; YSYERRI; -. DR OrthoDB; 11387at2759; -. DR Proteomes; UP000015464; Unassembled WGS sequence. DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. DR CDD; cd14480; SPX_VTC2_like; 1. DR Gene3D; 3.20.100.30; VTC, catalytic tunnel domain; 1. DR InterPro; IPR003807; DUF202. DR InterPro; IPR004331; SPX_dom. DR InterPro; IPR018966; VTC_domain. DR InterPro; IPR042267; VTC_sf. DR PANTHER; PTHR46140; VACUOLAR TRANSPORTER CHAPERONE 1-RELATED; 1. DR PANTHER; PTHR46140:SF2; VACUOLAR TRANSPORTER CHAPERONE 2-RELATED; 1. DR Pfam; PF02656; DUF202; 1. DR Pfam; PF09359; VTC; 1. DR PROSITE; PS51382; SPX; 1. PE 4: Predicted; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000015464}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}. FT TRANSMEM 624..642 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 654..672 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 692..712 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 1..144 FT /note="SPX" FT /evidence="ECO:0000259|PROSITE:PS51382" FT REGION 323..342 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 323..337 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 736 AA; 85745 MW; 446B39D103E6DDFF CRC64; MRFSDSLEAG IYQPWREHYM DYVKLKQFLK ADEESPVWGE NDESRFVSAL DDQLEKVYGF HQKIWKDLNE SLTSIEARFS SSNEFTDESL TNEDRLKLLE QLDSCTELVK KLEKYTRLNL TGFYKIVKKH DKLHSAYSLR PILQVRLRAC SLGNVQYNPI LARIFALYNP LRASLTGGQP SLNAPRHIHS SDDNVYRRRT YRFWVHHDNL MEVKTFIMRR LPVLYYSGKH GFDRDRSAVS GVLDPISTCL YFDNPNFDLY SQNLERSERA FSLRLHWYGK LNSKTDIIVE RMVREGSSLS HSEDRFVLRE KKLNEFLKEA YDPERKKSRD DSTDVSADSS QKKQLTEDVQ KLITEYNLQP VLRSVYTRTA FQIPGDDSVR VNLDSDWVMI REDSFDQERP CRDPIDWHRH DIDDAEFPYK HLRKGEHFRF PYSILEIREC LKPDEEEPLW VSELRSSHLI SEVDGFSKYE HGVAVLFERY VPLLPMWLFS MEQDIRKDPE TTYPVSKDTA SSSNIYVKRR DETVFTSESP PKTFKKAPVV SRRSQAPNAE MAAPHIQQFK HPHGDRFNFK SIPGLLKPST YGSIYRPGKT YTTPPHIQKP EVPLRVSGPV KVETKVWLAN ERTYLNWLHV VVLFGSLSLA LFNSANAKTG RIFGSIYVML AVFMGFYAWR LHAKRCNLIM TRSPAPMTEY RGPLFVGVAL AISLIANMTF ALRGAVEQNL IEDDHVLVKI FCKQFF //