ID S4SKA8_CILMU Unreviewed; 234 AA. AC S4SKA8; DT 16-OCT-2013, integrated into UniProtKB/TrEMBL. DT 16-OCT-2013, sequence version 1. DT 29-MAY-2024, entry version 28. DE RecName: Full=Cytochrome b {ECO:0000256|ARBA:ARBA00013531}; DE AltName: Full=Complex III subunit 3 {ECO:0000256|ARBA:ARBA00031681}; DE AltName: Full=Complex III subunit III {ECO:0000256|ARBA:ARBA00032600}; DE AltName: Full=Cytochrome b-c1 complex subunit 3 {ECO:0000256|ARBA:ARBA00029812}; DE AltName: Full=Ubiquinol-cytochrome-c reductase complex cytochrome b subunit {ECO:0000256|ARBA:ARBA00032818}; DE Flags: Fragment; GN Name=cytb {ECO:0000313|EMBL:AFO72871.1}; OS Ciliata mustela (Fivebeard rockling) (Gadus mustela). OG Mitochondrion {ECO:0000313|EMBL:AFO72871.1}. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Zeiogadaria; Gadariae; Gadiformes; Gadoidei; Lotidae; Ciliata. OX NCBI_TaxID=348443 {ECO:0000313|EMBL:AFO72871.1}; RN [1] {ECO:0000313|EMBL:AFO72871.1} RP NUCLEOTIDE SEQUENCE. RA Robalo J.I., Lima C.S., Francisco S.M., Almada F., Banon R., RA Villegas-Rios D., Almada V.C.; RT "Monitoring Climate Change Impact on the Genetic Population Structure: The RT Case of the Fivebeard Rockling (Ciliata Mustela, Linnaeus, 1758) In Its RT Southern Limit of Distribution."; RL J Phylogenetics Evol Biol 2:1-6(2013). CC -!- FUNCTION: Component of the ubiquinol-cytochrome c reductase complex CC (complex III or cytochrome b-c1 complex) that is part of the CC mitochondrial respiratory chain. The b-c1 complex mediates electron CC transfer from ubiquinol to cytochrome c. Contributes to the generation CC of a proton gradient across the mitochondrial membrane that is then CC used for ATP synthesis. {ECO:0000256|ARBA:ARBA00002566}. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion CC inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane CC protein {ECO:0000256|ARBA:ARBA00004448}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JX127121; AFO72871.1; -; Genomic_DNA. DR AlphaFoldDB; S4SKA8; -. DR GO; GO:0005750; C:mitochondrial respiratory chain complex III; IEA:TreeGrafter. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0008121; F:ubiquinol-cytochrome-c reductase activity; IEA:TreeGrafter. DR GO; GO:0006122; P:mitochondrial electron transport, ubiquinol to cytochrome c; IEA:TreeGrafter. DR CDD; cd00284; Cytochrome_b_N; 1. DR InterPro; IPR005798; Cyt_b/b6_C. DR InterPro; IPR005797; Cyt_b/b6_N. DR InterPro; IPR027387; Cytb/b6-like_sf. DR InterPro; IPR048259; Cytochrome_b_N_euk/bac. DR InterPro; IPR016174; Di-haem_cyt_TM. DR PANTHER; PTHR19271; CYTOCHROME B; 1. DR PANTHER; PTHR19271:SF16; CYTOCHROME B; 1. DR Pfam; PF00033; Cytochrome_B; 1. DR SUPFAM; SSF81342; Transmembrane di-heme cytochromes; 1. DR PROSITE; PS51003; CYTB_CTER; 1. DR PROSITE; PS51002; CYTB_NTER; 1. PE 4: Predicted; KW Electron transport {ECO:0000256|ARBA:ARBA00022982}; KW Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}; KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128, ECO:0000313|EMBL:AFO72871.1}; KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792}; KW Respiratory chain {ECO:0000256|ARBA:ARBA00022660}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}; KW Ubiquinone {ECO:0000256|ARBA:ARBA00023075}. FT TRANSMEM 18..41 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 76..96 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 102..122 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 167..188 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 209..233 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 1..198 FT /note="Cytochrome b/b6 N-terminal region profile" FT /evidence="ECO:0000259|PROSITE:PS51002" FT DOMAIN 199..234 FT /note="Cytochrome b/b6 C-terminal region profile" FT /evidence="ECO:0000259|PROSITE:PS51003" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:AFO72871.1" FT NON_TER 234 FT /evidence="ECO:0000313|EMBL:AFO72871.1" SQ SEQUENCE 234 AA; 26335 MW; DE0C8FADAA886942 CRC64; KIVNDAVVDL PTPSNISVWW NFGSLLGLCL ITQILTGLFL AMHYTSDIET AFSSVVHICR DVNYGWLIRN MHANGASFFF ICLYMHIARG LYYGSYLFVE TWNIGVVLFL LVMMTSFVGY VLPWGQMSFW GSTVITNLMS TVPYIGNNLV QWIWGGFSVD NATLTRFFAF HFLFPFIIAA ATMLHLLFLH ETGSNNPTGI SSNADKISFH PYFTYKDLLG FAVLLLGLTS LALF //