ID S4S3A3_GERHE Unreviewed; 607 AA. AC S4S3A3; DT 16-OCT-2013, integrated into UniProtKB/TrEMBL. DT 16-OCT-2013, sequence version 1. DT 27-NOV-2024, entry version 30. DE SubName: Full=BRCA1 {ECO:0000313|EMBL:AEI70621.1}; DE Flags: Fragment; OS Gerbillus henleyi (Pygmy gerbil) (Henley's gerbil). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Gerbillinae; Gerbillus. OX NCBI_TaxID=52284 {ECO:0000313|EMBL:AEI70621.1}; RN [1] {ECO:0000313|EMBL:AEI70621.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=ABC-01 {ECO:0000313|EMBL:AEI70621.1}; RA Granjon L., Colangelo P., Tatard C., Colyn M., Dobigny G., Nicolas V.; RT "Intrageneric relationships within Gerbilliscus (Rodentia, Muridae, RT Gerbillinae), with characterization of an additional West African RT species."; RL Zootaxa 3325:1-25(2012). CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JF716023; AEI70621.1; -; Genomic_DNA. DR GO; GO:0006281; P:DNA repair; IEA:InterPro. DR InterPro; IPR031099; BRCA1-associated. DR InterPro; IPR025994; BRCA1_serine_dom. DR Pfam; PF12820; BRCT_assoc; 1. DR PIRSF; PIRSF001734; BRCA1; 1. PE 4: Predicted; KW DNA damage {ECO:0000256|ARBA:ARBA00022763}; KW DNA repair {ECO:0000256|ARBA:ARBA00023204}. FT DOMAIN 9..166 FT /note="BRCA1 serine-rich" FT /evidence="ECO:0000259|Pfam:PF12820" FT REGION 191..226 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 280..407 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 549..607 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 191..214 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 285..310 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 331..353 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 354..371 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 549..563 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 564..578 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:AEI70621.1" FT NON_TER 607 FT /evidence="ECO:0000313|EMBL:AEI70621.1" SQ SEQUENCE 607 AA; 66735 MW; A5DA08B0B4260C28 CRC64; EKKVDFIADS LCGRKICNDE KSLCREDSGA TQNVPWTTLN SSVRKVNEWF SRTGEMLTSD RRQAASAEAA AALEVSNEVD GCDSNSKKIG LVTSDPHQDL MCKSERDFSK PVKNNINDKI FGKTYQRKGS LPHFNHVTEI IGTFTAEPQT TQAQPFTNKL KRKRRSTCLY PEDFIKKADL TIVQKTSENI NQGTDQMEPN DQVMGITSNG QENETKSNDL REEKTANPVE SLGEESAFTA KARPISNSIS DLEIKLNVYN SNAPKKNRLR RKASTVCIPA LEPMSRNPSS PTHAELQIDS FSSSEGKKKN NSDQAPVRHI RKPPLTADPE PAPEAKKKEP SEQVRKRTAS DAFSEEKLPS TDSSSSSDPE GPVKPSPXRK EXEKLEXSKV PANTXELXDL VXGGXXXXXX XXXXXXTSVS LVADTDYDTQ NSVSGLEANA VRSAKTGSIQ CLTQFVASEN TKELVRGSKD AGSPTECFQH PSRRELNHIS ETVEMEGSEL DTQYLQNTFQ ISKRQSFALF SKPRSPLNEC ATVSTHSLLS SLRELRPSVT SESKEDQVRE ESEISHAQAV TATVNLPVLR QQGKPGADTL CAGVSGLCPS SQHRSNE //