ID S4R187_MOUSE Unreviewed; 978 AA. AC S4R187; DT 18-SEP-2013, integrated into UniProtKB/TrEMBL. DT 18-SEP-2013, sequence version 1. DT 25-MAY-2022, entry version 54. DE SubName: Full=Ankyrin-3 {ECO:0000313|Ensembl:ENSMUSP00000138123}; GN Name=Ank3 {ECO:0000313|Ensembl:ENSMUSP00000138123, GN ECO:0000313|MGI:MGI:88026}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000138123, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000138123, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000138123, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0007829|PubMed:21183079} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001; RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.; RT "A tissue-specific atlas of mouse protein phosphorylation and expression."; RL Cell 143:1174-1189(2010). RN [3] {ECO:0000313|Ensembl:ENSMUSP00000138123} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000138123}; RG Ensembl; RL Submitted (JUL-2013) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR SMR; S4R187; -. DR jPOST; S4R187; -. DR PeptideAtlas; S4R187; -. DR ProteomicsDB; 359484; -. DR Antibodypedia; 4197; 296 antibodies from 27 providers. DR Ensembl; ENSMUST00000182269.8; ENSMUSP00000138123.2; ENSMUSG00000069601.15. DR MGI; MGI:88026; Ank3. DR VEuPathDB; HostDB:ENSMUSG00000069601; -. DR GeneTree; ENSGT01040000242009; -. DR ChiTaRS; Ank3; mouse. DR Proteomes; UP000000589; Chromosome 10. DR Bgee; ENSMUSG00000069601; Expressed in ventral horn of spinal cord and 307 other tissues. DR GO; GO:0007165; P:signal transduction; IEA:InterPro. DR CDD; cd08803; Death_ank3; 1. DR Gene3D; 1.10.533.10; -; 1. DR InterPro; IPR037971; Ank3_Death. DR InterPro; IPR040745; Ankyrin_UPA. DR InterPro; IPR011029; DEATH-like_dom_sf. DR InterPro; IPR000488; Death_domain. DR InterPro; IPR000906; ZU5_dom. DR Pfam; PF00531; Death; 1. DR Pfam; PF17809; UPA_2; 1. DR Pfam; PF00791; ZU5; 1. DR SMART; SM00005; DEATH; 1. DR SMART; SM00218; ZU5; 1. DR SUPFAM; SSF47986; SSF47986; 1. DR PROSITE; PS50017; DEATH_DOMAIN; 1. DR PROSITE; PS51145; ZU5; 2. PE 1: Evidence at protein level; KW Proteomics identification {ECO:0007829|MaxQB:S4R187, KW ECO:0007829|PeptideAtlas:S4R187}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT DOMAIN 117..272 FT /note="ZU5" FT /evidence="ECO:0000259|PROSITE:PS51145" FT DOMAIN 274..421 FT /note="ZU5" FT /evidence="ECO:0000259|PROSITE:PS51145" FT DOMAIN 598..682 FT /note="Death" FT /evidence="ECO:0000259|PROSITE:PS50017" FT REGION 1..24 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 842..870 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 842..863 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 978 AA; 108905 MW; FAAF55BA234B5208 CRC64; MALPHSEDAI TGDTDKYLGP QDLKELGDDS LPAEGYVGFS LGARSASPKI SSDRSYTLNR SSYARDSMMI EELLVPSKEQ HLTFTREFDS DSLRHYSWAA DTLDNVNLVS SPVHSGFLVS FMVDARGGSM RGSRHHGMRI IIPPRKCTAP TRITCRLVKR HKLANPPPMV EGEGLASRLV EMGPAGAQFL GPVIVEIPHF GSMRGKEREL IVLRSENGET WKEHQFDSKN EDLAELLNGM DEELDSPEEL GTKRICRIIT KDFPQYFAVV SRIKQESNQI GPEGGILSST TVPLVQASFP EGALTKRIRV GLQAQPVPEE TVKKILGNKA TFSPIVTVEP RRRKFHKPIT MTIPVPPPSG EGVSNGYKGD ATPNLRLLCS ITGGTSPAQW EDITGTTPLT FIKDCVSFTT NVSARFWLAD CHQVLETVGL ASQLYRELIC VPYMAKFVVF AKTNDPVESS LRCFCMTDDR VDKTLEQQEN FEEVARSKDI EVLEGKPIYV DCYGNLAPLT KGGQQLVFNF YSFKENRLPF SIKIRDTSQE PCGRLSFLKE PKTTKGLPQT AVCNLNITLP AHKKAEKADR RQSFASLALR PQSPCERTDI RMAIVADHLG LSWTELAREL NFSVDEINQI RVENPNSLIS QSFMLLKKWV TRDGKNATTD ALTSVLTKIN RIDIVTLLEG PIFDYGNISG TRSFADENNV FHDPVDGWQN ETPSGSLESP AQARRLTGGL LDRLDDSSDQ ARDSITSYLT GEPGKIEANG NHTAEVIPEA KAKPYFPESQ NDIGKQSIKE NLKPKTHGCG RTEEPVSPLT AYQKSLEETS KLVIEDAPKP CVPVGMKKMT RTTADGKARL NLQEEEGSTR SEPKVKSPGE AFTRMTACCY KDLRNSESDS SSEEEQRITT RVIRRRVIIK GEEAKNIPGE SVTEEQFTDE EGNLITRKIT RKVIRRIGPQ ERKQDDVQGE GYKVKTKKEI RNVEKKTH //