ID S4R187_MOUSE Unreviewed; 978 AA. AC S4R187; DT 18-SEP-2013, integrated into UniProtKB/TrEMBL. DT 18-SEP-2013, sequence version 1. DT 09-DEC-2015, entry version 18. DE SubName: Full=Ankyrin-3 {ECO:0000313|Ensembl:ENSMUSP00000138123}; GN Name=Ank3 {ECO:0000313|Ensembl:ENSMUSP00000138123, GN ECO:0000313|MGI:MGI:88026}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000138123, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000138123, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000138123, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000213|PubMed:21183079} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001; RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.; RT "A tissue-specific atlas of mouse protein phosphorylation and RT expression."; RL Cell 143:1174-1189(2010). RN [3] {ECO:0000313|Ensembl:ENSMUSP00000138123} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000138123}; RG Ensembl; RL Submitted (JUL-2013) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000138123}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC100427; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC129018; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC132435; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC156836; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR ProteinModelPortal; S4R187; -. DR SMR; S4R187; 115-695. DR STRING; 10090.ENSMUSP00000090090; -. DR PaxDb; S4R187; -. DR Ensembl; ENSMUST00000182269; ENSMUSP00000138123; ENSMUSG00000069601. DR MGI; MGI:88026; Ank3. DR eggNOG; COG0666; LUCA. DR eggNOG; KOG4177; Eukaryota. DR GeneTree; ENSGT00760000118950; -. DR ChiTaRS; Ank3; mouse. DR Proteomes; UP000000589; Chromosome 10. DR ExpressionAtlas; S4R187; baseline and differential. DR GO; GO:0030424; C:axon; IDA:MGI. DR GO; GO:0043194; C:axon initial segment; IDA:MGI. DR GO; GO:0016323; C:basolateral plasma membrane; ISO:MGI. DR GO; GO:0014704; C:intercalated disc; IDA:MGI. DR GO; GO:0005622; C:intracellular; ISO:GOC. DR GO; GO:0016328; C:lateral plasma membrane; ISO:MGI. DR GO; GO:0016020; C:membrane; IDA:MGI. DR GO; GO:0033270; C:paranode region of axon; IDA:MGI. DR GO; GO:0042383; C:sarcolemma; ISO:MGI. DR GO; GO:0045202; C:synapse; IDA:MGI. DR GO; GO:0005200; F:structural constituent of cytoskeleton; ISO:MGI. DR GO; GO:0007411; P:axon guidance; IMP:MGI. DR GO; GO:0045184; P:establishment of protein localization; ISO:MGI. DR GO; GO:0043001; P:Golgi to plasma membrane protein transport; ISO:MGI. DR GO; GO:0072660; P:maintenance of protein location in plasma membrane; ISO:MGI. DR GO; GO:0071709; P:membrane assembly; ISO:MGI. DR GO; GO:0000281; P:mitotic cytokinesis; ISO:MGI. DR GO; GO:0007009; P:plasma membrane organization; ISO:MGI. DR GO; GO:0072659; P:protein localization to plasma membrane; ISO:MGI. DR GO; GO:0072661; P:protein targeting to plasma membrane; ISO:MGI. DR GO; GO:0007165; P:signal transduction; IEA:InterPro. DR GO; GO:0050808; P:synapse organization; IMP:MGI. DR Gene3D; 1.10.533.10; -; 1. DR InterPro; IPR011029; DEATH-like_dom. DR InterPro; IPR000488; Death_domain. DR InterPro; IPR000906; ZU5_dom. DR Pfam; PF00531; Death; 1. DR Pfam; PF00791; ZU5; 1. DR SMART; SM00005; DEATH; 1. DR SMART; SM00218; ZU5; 1. DR SUPFAM; SSF47986; SSF47986; 1. DR PROSITE; PS50017; DEATH_DOMAIN; 1. DR PROSITE; PS51145; ZU5; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Proteomics identification {ECO:0000213|MaxQB:S4R187, KW ECO:0000213|PeptideAtlas:S4R187}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT DOMAIN 115 222 ZU5. {ECO:0000259|PROSITE:PS51145}. FT DOMAIN 598 682 Death. {ECO:0000259|PROSITE:PS50017}. SQ SEQUENCE 978 AA; 108905 MW; FAAF55BA234B5208 CRC64; MALPHSEDAI TGDTDKYLGP QDLKELGDDS LPAEGYVGFS LGARSASPKI SSDRSYTLNR SSYARDSMMI EELLVPSKEQ HLTFTREFDS DSLRHYSWAA DTLDNVNLVS SPVHSGFLVS FMVDARGGSM RGSRHHGMRI IIPPRKCTAP TRITCRLVKR HKLANPPPMV EGEGLASRLV EMGPAGAQFL GPVIVEIPHF GSMRGKEREL IVLRSENGET WKEHQFDSKN EDLAELLNGM DEELDSPEEL GTKRICRIIT KDFPQYFAVV SRIKQESNQI GPEGGILSST TVPLVQASFP EGALTKRIRV GLQAQPVPEE TVKKILGNKA TFSPIVTVEP RRRKFHKPIT MTIPVPPPSG EGVSNGYKGD ATPNLRLLCS ITGGTSPAQW EDITGTTPLT FIKDCVSFTT NVSARFWLAD CHQVLETVGL ASQLYRELIC VPYMAKFVVF AKTNDPVESS LRCFCMTDDR VDKTLEQQEN FEEVARSKDI EVLEGKPIYV DCYGNLAPLT KGGQQLVFNF YSFKENRLPF SIKIRDTSQE PCGRLSFLKE PKTTKGLPQT AVCNLNITLP AHKKAEKADR RQSFASLALR PQSPCERTDI RMAIVADHLG LSWTELAREL NFSVDEINQI RVENPNSLIS QSFMLLKKWV TRDGKNATTD ALTSVLTKIN RIDIVTLLEG PIFDYGNISG TRSFADENNV FHDPVDGWQN ETPSGSLESP AQARRLTGGL LDRLDDSSDQ ARDSITSYLT GEPGKIEANG NHTAEVIPEA KAKPYFPESQ NDIGKQSIKE NLKPKTHGCG RTEEPVSPLT AYQKSLEETS KLVIEDAPKP CVPVGMKKMT RTTADGKARL NLQEEEGSTR SEPKVKSPGE AFTRMTACCY KDLRNSESDS SSEEEQRITT RVIRRRVIIK GEEAKNIPGE SVTEEQFTDE EGNLITRKIT RKVIRRIGPQ ERKQDDVQGE GYKVKTKKEI RNVEKKTH //