ID R4IPV5_PSECR Unreviewed; 55 AA. AC R4IPV5; DT 24-JUL-2013, integrated into UniProtKB/TrEMBL. DT 24-JUL-2013, sequence version 1. DT 10-MAY-2017, entry version 19. DE RecName: Full=ATP synthase protein 8 {ECO:0000256|RuleBase:RU003661, ECO:0000256|SAAS:SAAS00400266}; GN Name=ATP8 {ECO:0000313|EMBL:AFV57260.1}; OS Pseudobagrus crassilabris (Bagrid catfish) (Leiocassis crassilabris). OG Mitochondrion {ECO:0000313|EMBL:AFV57260.1}. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes; OC Bagridae; Pseudobagrus. OX NCBI_TaxID=175786 {ECO:0000313|EMBL:AFV57260.1}; RN [1] {ECO:0000313|EMBL:AFV57260.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=23311344; RA Liang H.W., Li Z., Zou G.W.; RT "Complete mitochondrial DNA genome of Leiocassis RT crassilabris(Siluriformes: Bagridae)."; RL Mitochondrial DNA 24:222-224(2013). RN [2] {ECO:0000313|EMBL:AGM51227.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=24512421; DOI=10.3109/19401736.2013.792067; RA Zhou L., Xie Z., Zhang Y.; RT "The complete mitochondrial genome of Leiocassis crassilabris RT (Teleostei, Siluriformes: Bagridae)."; RL Mitochondrial DNA 25:183-184(2014). CC -!- FUNCTION: Mitochondrial membrane ATP synthase (F(1)F(0) ATP CC synthase or Complex V) produces ATP from ADP in the presence of a CC proton gradient across the membrane which is generated by electron CC transport complexes of the respiratory chain. F-type ATPases CC consist of two structural domains, F(1) - containing the CC extramembraneous catalytic core and F(0) - containing the membrane CC proton channel, linked together by a central stalk and a CC peripheral stalk. During catalysis, ATP synthesis in the catalytic CC domain of F(1) is coupled via a rotary mechanism of the central CC stalk subunits to proton translocation. CC {ECO:0000256|SAAS:SAAS00585567}. CC -!- SUBUNIT: F-type ATPases have 2 components, CF(1) - the catalytic CC core - and CF(0) - the membrane proton channel. CC {ECO:0000256|SAAS:SAAS00585553}. CC -!- SUBCELLULAR LOCATION: Mitochondrion membrane CC {ECO:0000256|RuleBase:RU003661, ECO:0000256|SAAS:SAAS00400291}; CC Single-pass membrane protein {ECO:0000256|RuleBase:RU003661, CC ECO:0000256|SAAS:SAAS00400291}. CC -!- SIMILARITY: Belongs to the ATPase protein 8 family. CC {ECO:0000256|RuleBase:RU003661, ECO:0000256|SAAS:SAAS00585545}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JX867257; AFV57260.1; -; Genomic_DNA. DR EMBL; KC768227; AGM51227.1; -; Genomic_DNA. DR RefSeq; YP_008080853.1; NC_021394.1. DR RefSeq; YP_008080853.1; NC_021394.1. DR RefSeq; YP_008080853.1; NC_021394.1. DR GeneID; 15822349; -. DR CTD; 4509; -. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0000276; C:mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); IEA:InterPro. DR GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro. DR GO; GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro. DR InterPro; IPR001421; ATP8_metazoa. DR Pfam; PF00895; ATP-synt_8; 1. PE 3: Inferred from homology; KW ATP synthesis {ECO:0000256|SAAS:SAAS00119314}; KW CF(0) {ECO:0000256|RuleBase:RU003661, ECO:0000256|SAAS:SAAS00119302}; KW Hydrogen ion transport {ECO:0000256|RuleBase:RU003661, KW ECO:0000256|SAAS:SAAS00478108}; KW Ion transport {ECO:0000256|RuleBase:RU003661, KW ECO:0000256|SAAS:SAAS00119304}; KW Membrane {ECO:0000256|SAAS:SAAS00119303, ECO:0000256|SAM:Phobius}; KW Mitochondrion {ECO:0000256|RuleBase:RU003661, KW ECO:0000256|SAAS:SAAS00119301, ECO:0000313|EMBL:AFV57260.1}; KW Transmembrane {ECO:0000256|RuleBase:RU003661, KW ECO:0000256|SAAS:SAAS00119312, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAAS:SAAS00119308, KW ECO:0000256|SAM:Phobius}; KW Transport {ECO:0000256|RuleBase:RU003661, KW ECO:0000256|SAAS:SAAS00478149}. FT TRANSMEM 6 24 Helical. {ECO:0000256|SAM:Phobius}. SQ SEQUENCE 55 AA; 6437 MW; 02DE5AE073F14FEA CRC64; MPQLNPAPWF AILVFSWLIF LTVIPNKVLN HTFTNEVTAL SAETLKSDTW NWPWH //