ID R4GN58_HUMAN Unreviewed; 95 AA. AC R4GN58; DT 26-JUN-2013, integrated into UniProtKB/TrEMBL. DT 26-JUN-2013, sequence version 1. DT 29-MAY-2024, entry version 50. DE SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000473499.1}; DE Flags: Fragment; GN Name=THOC1 {ECO:0000313|Ensembl:ENSP00000473499.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000473499.1, ECO:0000313|Proteomes:UP000005640}; RN [1] {ECO:0000313|Ensembl:ENSP00000473499.1, ECO:0000313|Proteomes:UP000005640} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=16177791; DOI=10.1038/nature03983; RA Nusbaum C., Zody M.C., Borowsky M.L., Kamal M., Kodira C.D., Taylor T.D., RA Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., RA Abouelleil A., Allen N.R., Anderson S., Bloom T., Bugalter B., Butler J., RA Cook A., DeCaprio D., Engels R., Garber M., Gnirke A., Hafez N., Hall J.L., RA Norman C.H., Itoh T., Jaffe D.B., Kuroki Y., Lehoczky J., Lui A., RA Macdonald P., Mauceli E., Mikkelsen T.S., Naylor J.W., Nicol R., Nguyen C., RA Noguchi H., O'Leary S.B., O'Neill K., Piqani B., Smith C.L., Talamas J.A., RA Topham K., Totoki Y., Toyoda A., Wain H.M., Young S.K., Zeng Q., RA Zimmer A.R., Fujiyama A., Hattori M., Birren B.W., Sakaki Y., Lander E.S.; RT "DNA sequence and analysis of human chromosome 18."; RL Nature 437:551-555(2005). RN [2] {ECO:0007829|PubMed:19608861} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=19608861; DOI=10.1126/science.1175371; RA Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., RA Olsen J.V., Mann M.; RT "Lysine acetylation targets protein complexes and co-regulates major RT cellular functions."; RL Science 325:834-840(2009). RN [3] {ECO:0000313|Ensembl:ENSP00000473499.1} RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2024) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AP000845; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR MassIVE; R4GN58; -. DR MaxQB; R4GN58; -. DR PeptideAtlas; R4GN58; -. DR Antibodypedia; 4748; 395 antibodies from 32 providers. DR Ensembl; ENST00000584642.1; ENSP00000473499.1; ENSG00000079134.13. DR UCSC; uc060msf.1; human. DR HGNC; HGNC:19070; THOC1. DR VEuPathDB; HostDB:ENSG00000079134; -. DR GeneTree; ENSGT00390000016232; -. DR HOGENOM; CLU_2391611_0_0_1; -. DR ChiTaRS; THOC1; human. DR Proteomes; UP000005640; Chromosome 18. DR Bgee; ENSG00000079134; Expressed in calcaneal tendon and 205 other cell types or tissues. DR ExpressionAtlas; R4GN58; baseline and differential. DR GO; GO:0000445; C:THO complex part of transcription export complex; IEA:TreeGrafter. DR GO; GO:0006406; P:mRNA export from nucleus; IEA:TreeGrafter. DR GO; GO:0032784; P:regulation of DNA-templated transcription elongation; IEA:TreeGrafter. DR InterPro; IPR021861; THO_THOC1. DR PANTHER; PTHR13265; THO COMPLEX SUBUNIT 1; 1. DR PANTHER; PTHR13265:SF2; THO COMPLEX SUBUNIT 1; 1. DR Pfam; PF11957; efThoc1; 1. PE 1: Evidence at protein level; KW Proteomics identification {ECO:0007829|EPD:R4GN58, KW ECO:0007829|MaxQB:R4GN58}; KW Reference proteome {ECO:0000313|Proteomes:UP000005640}. FT NON_TER 1 FT /evidence="ECO:0000313|Ensembl:ENSP00000473499.1" SQ SEQUENCE 95 AA; 11267 MW; CBEF9276276211F9 CRC64; XEGEMGDEEA PTTCSIPIDY NLYRKFWSLQ DYFRNPVQCY EKISWKTFLK YSEEVLAVFK SYKLDDTQAS RKKMEELKTG GEHVYFAKFL TSEKV //