ID R4GN58_HUMAN Unreviewed; 95 AA. AC R4GN58; DT 26-JUN-2013, integrated into UniProtKB/TrEMBL. DT 26-JUN-2013, sequence version 1. DT 11-DEC-2019, entry version 29. DE SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000473499}; DE Flags: Fragment; GN Name=THOC1 {ECO:0000313|Ensembl:ENSP00000473499}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000473499, ECO:0000313|Proteomes:UP000005640}; RN [1] {ECO:0000313|Ensembl:ENSP00000473499, ECO:0000313|Proteomes:UP000005640} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=16177791; DOI=10.1038/nature03983; RA Nusbaum C., Zody M.C., Borowsky M.L., Kamal M., Kodira C.D., Taylor T.D., RA Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., RA Abouelleil A., Allen N.R., Anderson S., Bloom T., Bugalter B., Butler J., RA Cook A., DeCaprio D., Engels R., Garber M., Gnirke A., Hafez N., Hall J.L., RA Norman C.H., Itoh T., Jaffe D.B., Kuroki Y., Lehoczky J., Lui A., RA Macdonald P., Mauceli E., Mikkelsen T.S., Naylor J.W., Nicol R., Nguyen C., RA Noguchi H., O'Leary S.B., O'Neill K., Piqani B., Smith C.L., Talamas J.A., RA Topham K., Totoki Y., Toyoda A., Wain H.M., Young S.K., Zeng Q., RA Zimmer A.R., Fujiyama A., Hattori M., Birren B.W., Sakaki Y., Lander E.S.; RT "DNA sequence and analysis of human chromosome 18."; RL Nature 437:551-555(2005). RN [2] {ECO:0000213|PubMed:19608861} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=19608861; DOI=10.1126/science.1175371; RA Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., RA Olsen J.V., Mann M.; RT "Lysine acetylation targets protein complexes and co-regulates major RT cellular functions."; RL Science 325:834-840(2009). RN [3] {ECO:0000313|Ensembl:ENSP00000473499} RP IDENTIFICATION. RG Ensembl; RL Submitted (MAY-2013) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AP000845; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR jPOST; R4GN58; -. DR MaxQB; R4GN58; -. DR PeptideAtlas; R4GN58; -. DR PRIDE; R4GN58; -. DR Ensembl; ENST00000584642; ENSP00000473499; ENSG00000079134. DR UCSC; uc060msf.1; human. DR EuPathDB; HostDB:ENSG00000079134.11; -. DR HGNC; HGNC:19070; THOC1. DR OpenTargets; ENSG00000079134; -. DR eggNOG; KOG2491; Eukaryota. DR eggNOG; ENOG410XQEX; LUCA. DR GeneTree; ENSGT00390000016232; -. DR ChiTaRS; THOC1; human. DR Proteomes; UP000005640; Chromosome 18. DR Bgee; ENSG00000079134; Expressed in 227 organ(s), highest expression level in kidney. DR ExpressionAtlas; R4GN58; baseline and differential. DR InterPro; IPR021861; THO_THOC1. DR PANTHER; PTHR13265; PTHR13265; 1. DR Pfam; PF11957; efThoc1; 1. PE 1: Evidence at protein level; KW Proteomics identification {ECO:0000213|EPD:R4GN58, KW ECO:0000213|MaxQB:R4GN58, ECO:0000213|PeptideAtlas:R4GN58, KW ECO:0000213|ProteomicsDB:R4GN58}; KW Reference proteome {ECO:0000313|Proteomes:UP000005640}. FT NON_TER 1 FT /evidence="ECO:0000313|Ensembl:ENSP00000473499" SQ SEQUENCE 95 AA; 11267 MW; CBEF9276276211F9 CRC64; XEGEMGDEEA PTTCSIPIDY NLYRKFWSLQ DYFRNPVQCY EKISWKTFLK YSEEVLAVFK SYKLDDTQAS RKKMEELKTG GEHVYFAKFL TSEKV //