ID CLIC1_MOUSE STANDARD; PRT; 240 AA. AC Q9Z1Q5; DT 30-MAY-2000 (Rel. 39, Created) DT 25-OCT-2004 (Rel. 45, Last sequence update) DT 10-MAY-2005 (Rel. 47, Last annotation update) DE Chloride intracellular channel protein 1 (Nuclear chloride ion channel DE 27) (NCC27) (p64 CLCP). GN Name=Clic1; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=129; RX PubMed=14656967; DOI=10.1101/gr.1736803; RA Xie T., Rowen L., Aguado B., Ahearn M.E., Madan A., Qin S., RA Campbell R.D., Hood L.; RT "Analysis of the gene-dense major histocompatibility complex class III RT region and its comparison to mouse."; RL Genome Res. 13:2621-2636(2003). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=FVB/N; TISSUE=Mammary gland; RX MEDLINE=22388257; PubMed=12477932; DOI=10.1073/pnas.242603899; RA Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., RA Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., RA Altschul S.F., Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., RA Hopkins R.F., Jordan H., Moore T., Max S.I., Wang J., Hsieh F., RA Diatchenko L., Marusina K., Farmer A.A., Rubin G.M., Hong L., RA Stapleton M., Soares M.B., Bonaldo M.F., Casavant T.L., Scheetz T.E., RA Brownstein M.J., Usdin T.B., Toshiyuki S., Carninci P., Prange C., RA Raha S.S., Loquellano N.A., Peters G.J., Abramson R.D., Mullahy S.J., RA Bosak S.A., McEwan P.J., McKernan K.J., Malek J.A., Gunaratne P.H., RA Richards S., Worley K.C., Hale S., Garcia A.M., Gay L.J., Hulyk S.W., RA Villalon D.K., Muzny D.M., Sodergren E.J., Lu X., Gibbs R.A., RA Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., RA Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G., RA Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., RA Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., RA Butterfield Y.S.N., Krzywinski M.I., Skalska U., Smailus D.E., RA Schnerch A., Schein J.E., Jones S.J.M., Marra M.A.; RT "Generation and initial analysis of more than 15,000 full-length human RT and mouse cDNA sequences."; RL Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903(2002). CC -!- FUNCTION: Seems to act as a chloride ion channel (By similarity). CC -!- SUBCELLULAR LOCATION: Nuclear and cytoplasmic (By similarity). CC -!- SIMILARITY: Belongs to the chloride channel CLIC family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF109905; AAC84155.1; -; Genomic_DNA. DR EMBL; BC004658; AAH04658.1; -; mRNA. DR HSSP; O00299; 1K0O. DR SMR; Q9Z1Q5; 5-240. DR Ensembl; ENSMUSG00000007041; Mus musculus. DR MGI; MGI:2148924; Clic1. DR InterPro; IPR004046; GST_Cterm. DR InterPro; IPR004045; GST_Nterm. DR InterPro; IPR002946; Int_Cl_channel. DR InterPro; IPR012336; Thioredoxin-like. DR InterPro; IPR012335; Thioredoxin_fold. DR Pfam; PF00043; GST_C; 1. DR PRINTS; PR01263; INTCLCHANNEL. DR TIGRFAMs; TIGR00862; O-ClC; 1. KW Acetylation; Chloride; Chloride channel; Ion transport; Ionic channel; KW Nuclear protein; Transport; Voltage-gated channel. FT INIT_MET 0 0 By similarity. FT MOD_RES 1 1 N-acetylalanine (By similarity). SQ SEQUENCE 240 AA; 26882 MW; EDB43BA5FD13C071 CRC64; AEEQPQVELF VKAGSDGAKI GNCPFSQRLF MVLWLKGVTF NVTTVDTKRR TETVQKLCPG GQLPFLLYGT EVHTDTNKIE EFLEAMLCPP RYPKLAALNP ESNTSGLDIF AKFSAYIKNS NPALNDNLEK GLLKALKVLD NYLTSPLPEE VDETSAEDEG ISQRKFLDGN ELTLADCNLL PKLHIVQVVC KKYRGFTIPE AFRGVHRYLS NAYAREEFAS TCPDDEEIEL AYEQVARALK //