ID MGD1_HUMAN STANDARD; PRT; 574 AA. AC Q9Y5V3; Q9UF36; DT 20-AUG-2001 (Rel. 40, Created) DT 20-AUG-2001 (Rel. 40, Last sequence update) DT 20-AUG-2001 (Rel. 40, Last annotation update) DE Melanoma-associated antigen D1 (MAGE-D1 antigen). GN MAGED1. OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP SEQUENCE FROM N.A. RC TISSUE=Bone marrow; RX MEDLINE=99339980; PubMed=10409427; RA Pold M., Zhou J., Chen G.L., Hall J.M., Vescio R.A., Berenson J.R.; RT "Identification of a new, unorthodox member of the MAGE gene family."; RL Genomics 59:161-167(1999). RN [2] RP SEQUENCE OF 99-574 FROM N.A. RC TISSUE=Testis; RA Blum H., Bauersachs S., Mewes H.-W., Gassenhuber J., Wiemann S.; RL Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases. CC -!- TISSUE SPECIFICITY: EXPRESSED IN BONE MARROW STROMAL CELLS FROM CC BOTH MULTIPLE MYELOMA PATIENTS AND HEALTHY DONORS. SEEMS TO BE CC UBIQUITOUSLY EXPRESSED. CC -!- SIMILARITY: BELONGS TO THE MAGE FAMILY. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF124440; AAD31421.1; -. DR EMBL; AL133628; CAB63752.1; -. DR MIM; 300224; -. DR InterPro; IPR002190; MAGE. DR Pfam; PF01454; MAGE; 1. KW Antigen; Multigene family; Repeat. FT DOMAIN 92 240 22 X 6 AA TANDEM REPEATS OF W-[PQ]-X-P-X- FT X. FT REPEAT 92 97 1. FT REPEAT 98 103 2. FT REPEAT 104 109 3. FT REPEAT 128 133 4. FT REPEAT 134 139 5. FT REPEAT 140 145 6. FT REPEAT 146 151 7. FT REPEAT 152 157 8. FT REPEAT 158 163 9. FT REPEAT 164 169 10. FT REPEAT 170 175 11. FT REPEAT 176 181 12. FT REPEAT 182 187 13. FT REPEAT 188 193 14. FT REPEAT 194 199 15. FT REPEAT 200 205 16. FT REPEAT 206 211 17. FT REPEAT 212 217 18. FT REPEAT 218 223 19. FT REPEAT 224 228 20 (IMPERFECT). FT REPEAT 229 234 21. FT REPEAT 235 240 22. SQ SEQUENCE 574 AA; 64823 MW; F7A9651400BDA052 CRC64; MATSQADIET DPGISEPDGA TAQTSADGSQ AQNLESRTII RGKRTRKINN LNVEENSSGD QRRAPLAAGT WRSAPVPVTT QNPPGAPPNV LWQTPLAWQN PSGWQNQTAR QTPPARQSPP ARQTPPAWQN PVAWQNPVIW PNPVIWQNPV IWPNPIVWPG PVVWPNPLAW QNPPGWQTPP GWQTPPGWQG PPDWQGPPDW PLPPDWPLPP DWPLPTDWPL PPDWIPADWP IPPDWQNLRP SPNLRPSPNS RASQNPGAAQ PRDVALLQER ANKLVKYLML KDYTKVPIKR SEMLRDIIRE YTDVYPEIIE RACFVLEKKF GIQLKEIDKE EHLYILISTP ESLAGILGTT KDTPKLGLLL VILGVIFMNG NRASEAVLWE ALRKMGLRPG VRHPLLGDLR KLLTYEFVKQ KYLDYRRVPN SNPPEYEFLW GLRSYHETSK MKVLRFIAEV QKRDPRDWTA QFMEAADEAL DALDAAAAEA EARAEARTRM GIGDEAVSGP WSWDDIEFEL LTWDEEGDFG DPWSRIPFTF WARYHQNARS RFPQTFAGPI IGPGGTASAN FAANFGAIGF FWVE //