ID Q9Y464_HUMAN Unreviewed; 865 AA. AC Q9Y464; DT 01-NOV-1999, integrated into UniProtKB/TrEMBL. DT 01-NOV-1999, sequence version 1. DT 27-NOV-2024, entry version 111. DE SubName: Full=Tenascin-X {ECO:0000313|EMBL:CAA76900.1}; DE Flags: Fragment; GN Name=XB {ECO:0000313|EMBL:CAA76900.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:CAA76900.1}; RN [1] {ECO:0000313|EMBL:CAA76900.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=7686164; DOI=10.1083/jcb.122.1.265; RA Bristow J., Tee M.K., Gitelman S.E., Mellon S.H., Miller W.L.; RT "Tenascin-X: a novel extracellular matrix protein encoded by the human XB RT gene overlapping P450c21B."; RL J. Cell Biol. 122:265-278(1993). RN [2] {ECO:0000313|EMBL:CAA76900.1} RP NUCLEOTIDE SEQUENCE. RA Exposito J.; RL Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|EMBL:CAA76900.1} RP NUCLEOTIDE SEQUENCE. RA Exposito J.Y., Elefteriou F., Garrone R., Lethias C.; RT "Human tenascin-X. Detection of new fibronectin-type III coding units and RT alternative splicing of its pre-mRNA."; RL Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; Y17866; CAA76900.1; -; mRNA. DR RefSeq; NP_061978.6; NM_019105.6. DR AlphaFoldDB; Q9Y464; -. DR DNASU; 7148; -. DR GeneID; 7148; -. DR KEGG; hsa:7148; -. DR CTD; 7148; -. DR DisGeNET; 7148; -. DR PharmGKB; PA36662; -. DR OrthoDB; 4251562at2759; -. DR BioGRID-ORCS; 7148; 16 hits in 1152 CRISPR screens. DR ChiTaRS; TNXB; human. DR CDD; cd00063; FN3; 8. DR FunFam; 2.60.40.10:FF:000024; Tenascin-X; 8. DR Gene3D; 2.60.40.10; Immunoglobulins; 8. DR InterPro; IPR050991; ECM_Regulatory_Proteins. DR InterPro; IPR003961; FN3_dom. DR InterPro; IPR036116; FN3_sf. DR InterPro; IPR013783; Ig-like_fold. DR PANTHER; PTHR46708; TENASCIN; 1. DR PANTHER; PTHR46708:SF3; TENASCIN-X; 1. DR Pfam; PF00041; fn3; 8. DR SMART; SM00060; FN3; 8. DR SUPFAM; SSF49265; Fibronectin type III; 7. DR PROSITE; PS50853; FN3; 8. PE 2: Evidence at transcript level; KW Repeat {ECO:0000256|ARBA:ARBA00022737}. FT DOMAIN 46..140 FT /note="Fibronectin type-III" FT /evidence="ECO:0000259|PROSITE:PS50853" FT DOMAIN 148..238 FT /note="Fibronectin type-III" FT /evidence="ECO:0000259|PROSITE:PS50853" FT DOMAIN 246..341 FT /note="Fibronectin type-III" FT /evidence="ECO:0000259|PROSITE:PS50853" FT DOMAIN 346..436 FT /note="Fibronectin type-III" FT /evidence="ECO:0000259|PROSITE:PS50853" FT DOMAIN 450..540 FT /note="Fibronectin type-III" FT /evidence="ECO:0000259|PROSITE:PS50853" FT DOMAIN 555..643 FT /note="Fibronectin type-III" FT /evidence="ECO:0000259|PROSITE:PS50853" FT DOMAIN 661..754 FT /note="Fibronectin type-III" FT /evidence="ECO:0000259|PROSITE:PS50853" FT DOMAIN 769..857 FT /note="Fibronectin type-III" FT /evidence="ECO:0000259|PROSITE:PS50853" FT REGION 1..59 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 424..449 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 640..663 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:CAA76900.1" FT NON_TER 865 FT /evidence="ECO:0000313|EMBL:CAA76900.1" SQ SEQUENCE 865 AA; 94027 MW; 723C942248DE440F CRC64; LYGLRGRQRV GPESVVAKTA PQEDVDETPS PTELGTEAPE SPEEPLLGEL TVTGSSPDSL SLFWTVPQGS FDSFTVQYKD RDGRPRAVRV GGKESEVTVG GLEPGHKYKM HLYGLHEGQR VGPVSAVGLT APQQEETPPA TESPLEPRLG ELTVTDVTPN SVGLSWTVPE GQFDSFIVQY KDKDGQPQVV PVAAGQREVT VYNLEPERKY KMNMYGLHDG QRMGPLSVVI VTAPLPPAPA TEASKPPLEP RLGELTVTDI TPDSVGLSWT VPEGEFDSFV VQYKDRDGQP QVVPVAADQR EVTIPDLEPS RKYKFLLFGI QDGKRRSPVS VEAKTVARGD ASPGAPPRLG ELWVTDPTPD SLRLSWTVPE GQFDSFVVQF KDKDGPQVVP VEGHERSVTV TPLDAGRKYR FLLYGLLGKK RHGPLTADGT TEARSAMDDT GTKRPPKPRL GEELQVTTVT QNSVGLSWTV PEGQFDSFVV QYKDRDGQPQ VVPVEGSLRE VSVPGLDPAH RYKLLLYGLH HGKRVGPISA VAITAGWEET ETETTAPTPP APEPHLGELT VEEATSHTLH LSWMVTEGEF DSFEIQYTDR DGQLQMVRIG GDRNDITLSG LESDHRYLVT LYGFSDGKHV GPVHVEALTV PEEEKPSEPP TATPEPPIKP RLGELTVTDA TPDSLSLSWT VPEGQFDHFL VQYRNGDGQP KAVRGPGHEE GVTISGLEPD HKYKMNLYGF HGGQRMGPVS VVGVTAAEEE TPSPTEPSME APEPAEEPLL GELTVTGSSP DSLSLSWTVP QGRFDSFTVQ YKDRDGRPQV VRVGGEESEV TVGGLEPGRK YKMHLYGLHE GRRVGPVSAV GVTAPEEESP DAPLA //