ID NOP16_HUMAN Reviewed; 178 AA. AC Q9Y3C1; Q6IAI6; Q8IXL5; DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot. DT 19-SEP-2006, sequence version 2. DT 10-FEB-2009, entry version 62. DE RecName: Full=Nucleolar protein 16; DE AltName: Full=HBV pre-S2 trans-regulated protein 3; GN Name=NOP16; ORFNames=CGI-117, HSPC111; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA]. RA Ji D., Cheng J., Dong J., Liu Y., Wang J.-J., Guo J.; RT "Screening and identification of genes trans-regulated by hepatitis B RT virus pre-S2 protein by microarray assay."; RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RX MEDLINE=20272150; PubMed=10810093; DOI=10.1101/gr.10.5.703; RA Lai C.-H., Chou C.-Y., Ch'ang L.-Y., Liu C.-S., Lin W.-C.; RT "Identification of novel human genes evolutionarily conserved in RT Caenorhabditis elegans by comparative proteomics."; RL Genome Res. 10:703-713(2000). RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Umbilical cord blood; RX MEDLINE=20499367; PubMed=11042152; DOI=10.1101/gr.140200; RA Zhang Q.-H., Ye M., Wu X.-Y., Ren S.-X., Zhao M., Zhao C.-J., Fu G., RA Shen Y., Fan H.-Y., Lu G., Zhong M., Xu X.-R., Han Z.-G., Zhang J.-W., RA Tao J., Huang Q.-H., Zhou J., Hu G.-X., Gu J., Chen S.-J., Chen Z.; RT "Cloning and functional analysis of cDNAs with open reading frames for RT 300 previously undefined genes expressed in CD34+ hematopoietic RT stem/progenitor cells."; RL Genome Res. 10:1546-1560(2000). RN [4] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RA Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.; RT "Cloning of human full open reading frames in Gateway(TM) system entry RT vector (pDONR201)."; RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases. RN [5] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Skin; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). RN [6] RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS], AND MASS SPECTROMETRY. RX MEDLINE=22317277; PubMed=12429849; DOI=10.1091/mbc.E02-05-0271; RA Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., RA Greco A., Hochstrasser D.F., Diaz J.-J.; RT "Functional proteomic analysis of human nucleolus."; RL Mol. Biol. Cell 13:4100-4109(2002). RN [7] RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-16 AND THR-144, AND MASS RP SPECTROMETRY. RX PubMed=18669648; DOI=10.1073/pnas.0805139105; RA Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., RA Elledge S.J., Gygi S.P.; RT "A quantitative atlas of mitotic phosphorylation."; RL Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). RN [8] RP IDENTIFICATION BY MASS SPECTROMETRY. RA Colinge J., Superti-Furga G., Bennett K.L.; RL Submitted (OCT-2008) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus. CC -!- SIMILARITY: Belongs to the NOP16 family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY561704; AAS66977.1; -; mRNA. DR EMBL; AF151875; AAD34112.1; -; mRNA. DR EMBL; AF161460; AAF29075.1; -; mRNA. DR EMBL; CR457169; CAG33450.1; -; mRNA. DR EMBL; BC040106; AAH40106.1; -; mRNA. DR IPI; IPI00032849; -. DR RefSeq; NP_057475.2; -. DR UniGene; Hs.696283; -. DR PhosphoSite; Q9Y3C1; -. DR SWISS-2DPAGE; Q9Y3C1; -. DR PRIDE; Q9Y3C1; -. DR Ensembl; ENSG00000048162; Homo sapiens. DR GeneID; 51491; -. DR KEGG; hsa:51491; -. DR GeneCards; GC05M175743; -. DR HGNC; HGNC:26934; NOP16. DR HOVERGEN; Q9Y3C1; -. DR LinkHub; Q9Y3C1; -. DR NextBio; 55154; -. DR ArrayExpress; Q9Y3C1; -. DR Bgee; Q9Y3C1; -. DR GermOnline; ENSG00000048162; Homo sapiens. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW. PE 1: Evidence at protein level; KW Nucleus; Phosphoprotein. FT CHAIN 1 178 Nucleolar protein 16. FT /FTId=PRO_0000050817. FT MOD_RES 16 16 Phosphoserine. FT MOD_RES 144 144 Phosphothreonine. FT CONFLICT 32 33 PR -> RG (in Ref. 2; AAD34112 and 3; FT AAF29075). FT CONFLICT 178 178 E -> D (in Ref. 4; CAG33450). SQ SEQUENCE 178 AA; 21188 MW; D9139BE32DA81FC5 CRC64; MPKAKGKTRR QKFGYSVNRK RLNRNARRKA APRIECSHIR HAWDHAKSVR QNLAEMGLAV DPNRAVPLRK RKVKAMEVDI EERPKELVRK PYVLNDLEAE ASLPEKKGNT LSRDLIDYVR YMVENHGEDY KAMARDEKNY YQDTPKQIRS KINVYKRFYP AEWQDFLDSL QKRKMEVE //