ID FXR2_MOUSE STANDARD; PRT; 673 AA. AC Q9WVR4; Q9WVR5; DT 28-FEB-2003 (Rel. 41, Created) DT 28-FEB-2003 (Rel. 41, Last sequence update) DT 24-JAN-2006 (Rel. 49, Last annotation update) DE Fragile X mental retardation syndrome-related protein 2. GN Name=Fxr2; Synonyms=Fxr2h; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=129; RX MEDLINE=99453761; PubMed=10524236; DOI=10.1016/S0378-1119(99)00301-7; RA Miyashita A., Shimizu N., Endo N., Hanyuu T., Ishii N., Ito K., RA Itoh Y., Shirai M., Nakajima T., Odani S., Kuwano R.; RT "Five different genes, Eif4a1, Cd68, Supl15h, Sox15 and Fxr2h, are RT clustered in a 40 kb region of mouse chromosome 11."; RL Gene 237:53-60(1999). CC -!- FUNCTION: RNA-binding protein (By similarity). CC -!- SUBUNIT: Interacts with FMR1 and FXR1 (By similarity). CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity). CC -!- SIMILARITY: Belongs to the FMR1 family. CC -!- SIMILARITY: Contains 2 KH domains. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB025311; BAA82249.1; -; Genomic_DNA. DR EMBL; AB025269; BAA82147.1; -; mRNA. DR HSSP; Q06787; 2FMR. DR SMR; Q9WVR4; 226-290. DR Ensembl; ENSMUSG00000018765; Mus musculus. DR MGI; MGI:1346074; Fxr2h. DR InterPro; IPR008395; Agenet. DR InterPro; IPR004087; KH. DR InterPro; IPR004088; KH_type_1. DR Pfam; PF05641; Agenet; 1. DR Pfam; PF00013; KH_1; 2. DR SMART; SM00322; KH; 2. DR PROSITE; PS50084; KH_TYPE_1; 2. KW Phosphorylation; Repeat; RNA-binding. FT DOMAIN 228 276 KH 1. FT DOMAIN 291 340 KH 2. FT COMPBIAS 416 420 Poly-Ser. FT COMPBIAS 483 486 Poly-Arg. FT COMPBIAS 545 553 Poly-Arg. FT COMPBIAS 585 595 Poly-Arg. FT MOD_RES 520 520 Phosphotyrosine (By similarity). SQ SEQUENCE 673 AA; 73743 MW; 01F6814D4C3B5654 CRC64; MGGLASGGDV EPGLPVEVRG SNGAFYKGFV KDVHEDSVTI FFENNWQSER QIPFGDVRLP PPADYNKEIT EGDEVEVYSR ANEQEPCGWC LARVRMMKGD FYVIEYAACD ATYNEIVTLE RLRPVNSSSL ATKGSFFKVT MAVPEDLREA CSNENVHKEF KKALGANCIF LNITNSELFI LSTTEAPVKR ASLLGDMHFR SLRTKLLLMS RNEEATKHLE TSKQLAAAFQ EEFTVREDLM GLAIGTHGAN IQQARKVPGV TAIELGEETC TFRIYGETPE ACRQARSYLE FSEDSVQVPR DLVGKVTGKT GKVIQGIVDK SGVVRVRVEG DNDKKNPKEG GMVPFIFVGT RENISNAQAL LEYHLSYLQE VETLRLERLQ IDEQLRQIGA GFRPPGSGRG GSGGGSDKAG YTTDESSSSS LHTTRTYGGS YGGRGRGRRT GGPAYGPSSD PSTASETESE KREESNRAGP GDRDPPSRGE ESRRRRLGPG KGPPPVPRPT SRYNSSSISS VLKDPDSNPY SLLDTSEPEP PVDSEPGEPP PASARRRRSR RRRTDEDRTV MDGALESDGP NMTENGLEDE SRPQRRNRSR RRRNRGNRTD GSISGDRQPV TVADYISRAE SQSRQRPLGR TEPSEDSLSG QKGDSVSKLP KGPSENGELS APLELGSLVN GVS //