ID   Q9VQJ0_DROME            Unreviewed;       444 AA.
AC   Q9VQJ0; Q24473; Q7KU23;
DT   01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 4.
DT   14-OCT-2015, entry version 134.
DE   SubName: Full=RNA-binding protein {ECO:0000313|EMBL:AAC13645.1};
DE   SubName: Full=RNA-binding protein 9, isoform B {ECO:0000313|EMBL:AAF51177.2};
DE   SubName: Full=RNA-binding protein 9, isoform C {ECO:0000313|EMBL:AAF51178.2};
DE   SubName: Full=RNA-binding protein 9, isoform I {ECO:0000313|EMBL:AAF51179.4};
DE   SubName: Full=RNA-binding protein 9, isoform K {ECO:0000313|EMBL:AHN54084.1};
GN   Name=Rbp9 {ECO:0000313|EMBL:AAF51179.4,
GN   ECO:0000313|FlyBase:FBgn0010263};
GN   Synonyms=RBP9 {ECO:0000313|EMBL:AAC13645.1};
GN   ORFNames=CG3151 {ECO:0000313|FlyBase:FBgn0010263}, Dmel_CG3151
GN   {ECO:0000313|EMBL:AAF51179.4};
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227 {ECO:0000313|EMBL:AAF51179.4, ECO:0000313|Proteomes:UP000000803};
RN   [1] {ECO:0000313|EMBL:AAC13645.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Canton S {ECO:0000313|EMBL:AAC13645.1};
RA   Kim Y.-J., Baker B.S.;
RT   "The Drosophila gene rbp9 encodes a protein that is a member of a
RT   conserved group of putative RNA binding proteins that are nervous
RT   system-specific inBoth flies and humans.";
RL   J. Neurosci. 0:0-0(1992).
RN   [2] {ECO:0000313|EMBL:AAF51179.4, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA   Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA   Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA   George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA   Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X.,
RA   Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D.,
RA   Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G.,
RA   Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D.,
RA   Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M.,
RA   Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S.,
RA   Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P.,
RA   Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I.,
RA   Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P.,
RA   de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M.,
RA   Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P.,
RA   Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W.,
RA   Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K.,
RA   Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA   Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J.,
RA   Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C.,
RA   Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A.,
RA   Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z.,
RA   Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X.,
RA   Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D.,
RA   Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A.,
RA   Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L.,
RA   Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M.,
RA   Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G.,
RA   Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H.,
RA   Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA   Spier E., Spradling A.C., Stapleton M., Strong R., Sun E.,
RA   Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X.,
RA   Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J.,
RA   Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A.,
RA   Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L.,
RA   Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X.,
RA   Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.;
RT   "The genome sequence of Drosophila melanogaster.";
RL   Science 287:2185-2195(2000).
RN   [3] {ECO:0000313|EMBL:AAF51179.4, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=12537568;
RA   Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A.,
RA   Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A.,
RA   George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R.,
RA   Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J.,
RA   Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C.,
RA   Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.;
RT   "Finishing a whole-genome shotgun: release 3 of the Drosophila
RT   melanogaster euchromatic genome sequence.";
RL   Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002).
RN   [4] {ECO:0000313|EMBL:AAF51179.4, ECO:0000313|Proteomes:UP000000803}
RP   GENOME REANNOTATION.
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA   Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA   Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA   Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA   Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA   Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q.,
RA   Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M.,
RA   Lewis S.E.;
RT   "Annotation of the Drosophila melanogaster euchromatic genome: a
RT   systematic review.";
RL   Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN   [5] {ECO:0000313|EMBL:AAF51179.4, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=12537573;
RA   Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R.,
RA   Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M.,
RA   Ashburner M., Celniker S.E.;
RT   "The transposable elements of the Drosophila melanogaster euchromatin:
RT   a genomics perspective.";
RL   Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002).
RN   [6] {ECO:0000313|EMBL:AAF51179.4, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=12537574;
RA   Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A.,
RA   Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G.,
RA   Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M.,
RA   Karpen G.H.;
RT   "Heterochromatic sequences in a Drosophila whole-genome shotgun
RT   assembly.";
RL   Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002).
RN   [7] {ECO:0000313|EMBL:AAF51179.4, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=16110336; DOI=10.1371/journal.pcbi.0010022;
RA   Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D.,
RA   Ashburner M., Anxolabehere D.;
RT   "Combined evidence annotation of transposable elements in genome
RT   sequences.";
RL   PLoS Comput. Biol. 1:166-175(2005).
RN   [8] {ECO:0000313|EMBL:AAF51179.4}
RP   NUCLEOTIDE SEQUENCE.
RA   Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S.,
RA   Svirskas R., Rubin G.;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN   [9] {ECO:0000313|EMBL:AAF51179.4}
RP   NUCLEOTIDE SEQUENCE.
RG   Berkeley Drosophila Genome Project;
RA   Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R.,
RA   Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E.,
RA   Yu C., Rubin G.;
RT   "Drosophila melanogaster release 4 sequence.";
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
RN   [10] {ECO:0000313|EMBL:AAF51179.4, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=17569856; DOI=10.1126/science.1139815;
RA   Smith C.D., Shu S., Mungall C.J., Karpen G.H.;
RT   "The Release 5.1 annotation of Drosophila melanogaster
RT   heterochromatin.";
RL   Science 316:1586-1591(2007).
RN   [11] {ECO:0000313|EMBL:AAF51179.4, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=17569867; DOI=10.1126/science.1139816;
RA   Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M.,
RA   Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A.,
RA   Dimitri P., Karpen G.H., Celniker S.E.;
RT   "Sequence finishing and mapping of Drosophila melanogaster
RT   heterochromatin.";
RL   Science 316:1625-1628(2007).
RN   [12] {ECO:0000313|EMBL:AAF51179.4}
RP   NUCLEOTIDE SEQUENCE.
RG   FlyBase;
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; L04930; AAC13645.1; -; Genomic_DNA.
DR   EMBL; AE014134; AAF51177.2; -; Genomic_DNA.
DR   EMBL; AE014134; AAF51178.2; -; Genomic_DNA.
DR   EMBL; AE014134; AAF51179.4; -; Genomic_DNA.
DR   EMBL; AE014134; AHN54084.1; -; Genomic_DNA.
DR   RefSeq; NP_001285569.1; NM_001298640.1.
DR   RefSeq; NP_476937.3; NM_057589.3.
DR   RefSeq; NP_599124.1; NM_134297.5.
DR   RefSeq; NP_599127.1; NM_134300.4.
DR   UniGene; Dm.4071; -.
DR   MINT; MINT-278111; -.
DR   STRING; 7227.FBpp0303246; -.
DR   GeneID; 33498; -.
DR   UCSC; CG3151-RB; d. melanogaster.
DR   CTD; 33498; -.
DR   FlyBase; FBgn0010263; Rbp9.
DR   Reactome; R-DME-450520; HuR stabilizes mRNA.
DR   GenomeRNAi; 33498; -.
DR   NextBio; 783890; -.
DR   Proteomes; UP000000803; Chromosome 2L.
DR   GO; GO:0005634; C:nucleus; TAS:FlyBase.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; TAS:FlyBase.
DR   GO; GO:0003729; F:mRNA binding; ISS:FlyBase.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0060856; P:establishment of blood-brain barrier; IMP:FlyBase.
DR   GO; GO:0036093; P:germ cell proliferation; IMP:FlyBase.
DR   GO; GO:0007293; P:germarium-derived egg chamber formation; TAS:FlyBase.
DR   GO; GO:0048477; P:oogenesis; IMP:FlyBase.
DR   Gene3D; 3.30.70.330; -; 3.
DR   InterPro; IPR006548; ELAD_HUD_SF.
DR   InterPro; IPR002343; Hud_Sxl_RNA.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait.
DR   InterPro; IPR000504; RRM_dom.
DR   Pfam; PF00076; RRM_1; 3.
DR   PRINTS; PR00961; HUDSXLRNA.
DR   SMART; SM00360; RRM; 3.
DR   TIGRFAMs; TIGR01661; ELAV_HUD_SF; 1.
DR   PROSITE; PS50102; RRM; 3.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000803};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:Q9VQJ0};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000803};
KW   Repeat {ECO:0000256|SAAS:SAAS00103864};
KW   RNA-binding {ECO:0000256|SAAS:SAAS00103867}.
SQ   SEQUENCE   444 AA;  46769 MW;  7DB4AD81EBA07598 CRC64;
     MVEGQTAVQQ QQQQPSGAGG ASGVGSTTGS AGGPATANNV TNSQAQTNGG TTATTTAAAG
     AGSTTNAAVG QATANNAASN NNNNNNNTNN NNNNNATANN NNNNEPDPKT NLIVNYLPQT
     MSQDEIRSLF VSFGEVESCK LIRDKVTGQS LGYGFVNYVK QEDAEKAINA LNGLRLQNKT
     IKVSIARPSS ESIKGANLYV SGLPKNMTQS DLESLFSPYG KIITSRILCD NITDEHAAGL
     SKGVGFIRFD QRFEADRAIK ELNGTTPKNS TEPITVKFAN NPSSNKNSMQ PLAAYIAPQN
     TRGGRAFPAN AAAGAAAAAA AAAIHPNAGR YSSVISRYSP LTSDLITNGM IQGNTIASSG
     WCIFVYNLAP DTEENVLWQL FGPFGAVQSV KVIRDLQSNK CKGFGFVTMT NYEEAVLAIQ
     SLNGYTLGNR VLQVSFKTNK NKQT
//