ID Q9VDR7_DROME Unreviewed; 829 AA. AC Q9VDR7; DT 01-MAY-2000, integrated into UniProtKB/TrEMBL. DT 01-OCT-2002, sequence version 2. DT 11-JUN-2014, entry version 87. DE SubName: Full=Miranda, isoform A; GN Name=mira; ORFNames=CG12249, Dmel_CG12249; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., RA Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., RA Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., RA Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX PubMed=12537568; RA Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., RA Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., RA George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., RA Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J., RA Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., RA Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.; RT "Finishing a whole-genome shotgun: release 3 of the Drosophila RT melanogaster euchromatic genome sequence."; RL Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002). RN [3] RP GENOME REANNOTATION. RC STRAIN=Berkeley; RX PubMed=12537572; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). RN [4] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX PubMed=12537573; RA Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., RA Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., RA Ashburner M., Celniker S.E.; RT "The transposable elements of the Drosophila melanogaster euchromatin: RT a genomics perspective."; RL Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002). RN [5] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX PubMed=12537574; RA Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., RA Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., RA Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., RA Karpen G.H.; RT "Heterochromatic sequences in a Drosophila whole-genome shotgun RT assembly."; RL Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002). RN [6] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX PubMed=16110336; DOI=10.1371/journal.pcbi.0010022; RA Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., RA Ashburner M., Anxolabehere D.; RT "Combined evidence annotation of transposable elements in genome RT sequences."; RL PLoS Comput. Biol. 1:166-175(2005). RN [7] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX PubMed=17569856; DOI=10.1126/science.1139815; RA Smith C.D., Shu S., Mungall C.J., Karpen G.H.; RT "The Release 5.1 annotation of Drosophila melanogaster RT heterochromatin."; RL Science 316:1586-1591(2007). RN [8] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX PubMed=17569867; DOI=10.1126/science.1139816; RA Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M., RA Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A., RA Dimitri P., Karpen G.H., Celniker S.E.; RT "Sequence finishing and mapping of Drosophila melanogaster RT heterochromatin."; RL Science 316:1625-1628(2007). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE014297; AAF55723.2; -; Genomic_DNA. DR RefSeq; NP_477291.1; NM_057943.4. DR UniGene; Dm.2993; -. DR ProteinModelPortal; Q9VDR7; -. DR MINT; MINT-1529648; -. DR EnsemblMetazoa; FBtr0083847; FBpp0083256; FBgn0021776. DR GeneID; 42379; -. DR KEGG; dme:Dmel_CG12249; -. DR UCSC; CG12249-RA; d. melanogaster. DR CTD; 100736249; -. DR FlyBase; FBgn0021776; mira. DR InParanoid; Q9VDR7; -. DR OMA; VEREKSY; -. DR PhylomeDB; Q9VDR7; -. DR GenomeRNAi; 42379; -. DR NextBio; 828512; -. DR PRO; PR:Q9VDR7; -. DR Bgee; Q9VDR7; -. DR GO; GO:0045179; C:apical cortex; IDA:FlyBase. DR GO; GO:0045177; C:apical part of cell; IDA:FlyBase. DR GO; GO:0016324; C:apical plasma membrane; IDA:FlyBase. DR GO; GO:0045180; C:basal cortex; IDA:FlyBase. DR GO; GO:0045178; C:basal part of cell; IDA:FlyBase. DR GO; GO:0009925; C:basal plasma membrane; IDA:FlyBase. DR GO; GO:0005938; C:cell cortex; IDA:FlyBase. DR GO; GO:0005813; C:centrosome; IDA:FlyBase. DR GO; GO:0005737; C:cytoplasm; IDA:FlyBase. DR GO; GO:0016020; C:membrane; IDA:UniProtKB. DR GO; GO:0003779; F:actin binding; ISS:FlyBase. DR GO; GO:0017022; F:myosin binding; IPI:FlyBase. DR GO; GO:0005515; F:protein binding; IPI:FlyBase. DR GO; GO:0008595; P:anterior/posterior axis specification, embryo; IMP:FlyBase. DR GO; GO:0055059; P:asymmetric neuroblast division; TAS:FlyBase. DR GO; GO:0008105; P:asymmetric protein localization; IMP:FlyBase. DR GO; GO:0045167; P:asymmetric protein localization involved in cell fate determination; TAS:FlyBase. DR GO; GO:0007402; P:ganglion mother cell fate determination; TAS:FlyBase. DR GO; GO:0008298; P:intracellular mRNA localization; NAS:FlyBase. DR GO; GO:0007400; P:neuroblast fate determination; TAS:FlyBase. DR GO; GO:0007405; P:neuroblast proliferation; IMP:FlyBase. DR GO; GO:0048477; P:oogenesis; IGI:FlyBase. DR GO; GO:0007317; P:regulation of pole plasm oskar mRNA localization; IMP:FlyBase. DR GO; GO:0030162; P:regulation of proteolysis; IMP:FlyBase. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 829 AA; 93101 MW; BE3AEFD4A454EEAF CRC64; MSFSKAKLKR FNDVDVAICG SPAASNSSAG SAGSATPTAS SAAAAPPTVQ PERKEQIEKF FKDAVRFASS SKEAKEFAIP KEDKKSKGLR LFRTPSLPQR LRFRPTPSHT DTATGSGSGA STAASTPLHS AATTPVKEAK SASRLKGKEA LQYEIRHKNE LIESQLSQLD VLRRHVDQLK EAEAKLREEH ELATSKTDRL IEALTSENLS HKALNEQMGQ EHADLLERLA AMEQQLQQQH DEHERQVEAL VAESEALRLA NELLQTANED RQKVEEQLQA QLSALQADVA QAREHCSLEQ AKTAENIELV ENLQKTNASL LADVVQLKQQ IEQDALSYGQ EAKSCQAELE CLKVERNTLK NDLANKCTLI RSLQDELLDK NCEIDAHCDT IRQLCREQAR HTEQQQAVAK VQQQVESDLE SAVEREKSYW RAELDKRQKL AENELIKIEL EKQDVMVLLE TTNDMLRMRD EKLQKCEEQL RNGIDYYIQL SDALQQQLVQ LKQDMAKTIT EKYNYQLTLT NTRATVNILM ERLKKSDADV EQYRAELESV QLAKGALEQS YLVLQADAEQ LRQQLTESQD ALNALRSSSQ TLQSEVSLKE SLLHELLAGE AETLAKFNQI ANSFQERIDG DAQLAHYHEL RRKDETREAY MVDMKKALDE FATVLQFAQL ELDNKEQMLV KVREECEQLK LENIALKSKQ PGSASLLGTP GKANRSNTTD LEKIEDLLCD SELRSDCEKI TTWLLNSSDK CVRQDTTSEI NELLSAGKSS PRPAPRTPKA PHTPRSPRTP HTPRTPRSAA STPKKTVLFA GKENVPSPPQ KQVLKARNI //