ID Q9VCN7_DROME Unreviewed; 915 AA. AC Q9VCN7; DT 01-MAY-2000, integrated into UniProtKB/TrEMBL. DT 01-MAY-2000, sequence version 1. DT 06-FEB-2013, entry version 99. DE SubName: Full=FI20148p1; DE SubName: Full=Oo18 RNA-binding protein, isoform A; GN Name=orb; Synonyms=orb-RA; ORFNames=Dmel_CG10868; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX MEDLINE=20196006; PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., RA Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., RA Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., RA Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [2] RP GENOME REANNOTATION. RC STRAIN=Berkeley; RX MEDLINE=22426069; PubMed=12537572; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). RN [3] RP NUCLEOTIDE SEQUENCE. RA Carlson J., Booth B., Frise E., Park S., Wan K., Yu C., Celniker S.; RL Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE014297; AAF56120.1; -; Genomic_DNA. DR EMBL; BT133433; AFH68357.1; -; mRNA. DR RefSeq; NP_524460.2; NM_079736.2. DR UniGene; Dm.1293; -. DR SMR; Q9VCN7; 574-682, 690-765. DR MINT; MINT-955759; -. DR STRING; Q9VCN7; -. DR EnsemblMetazoa; FBtr0084384; FBpp0083776; FBgn0004882. DR GeneID; 42752; -. DR KEGG; dme:Dmel_CG10868; -. DR UCSC; CG10868-RA; d. melanogaster. DR CTD; 42752; -. DR FlyBase; FBgn0004882; orb. DR GeneTree; ENSGT00390000012886; -. DR InParanoid; Q9VCN7; -. DR KO; K02602; -. DR OMA; FFKISSR; -. DR GenomeRNAi; 42752; -. DR NextBio; 830386; -. DR ArrayExpress; Q9VCN7; -. DR GO; GO:0005737; C:cytoplasm; IDA:FlyBase. DR GO; GO:0003729; F:mRNA binding; ISS:FlyBase. DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro. DR GO; GO:0048134; P:germ-line cyst formation; TAS:FlyBase. DR GO; GO:0007294; P:germarium-derived oocyte fate determination; TAS:FlyBase. DR GO; GO:0006378; P:mRNA polyadenylation; IMP:FlyBase. DR GO; GO:0007310; P:oocyte dorsal/ventral axis specification; IMP:FlyBase. DR GO; GO:0045451; P:pole plasm oskar mRNA localization; IMP:FlyBase. DR GO; GO:0046012; P:positive regulation of oskar mRNA translation; NAS:FlyBase. DR Gene3D; 3.30.70.330; a_b_plait_nuc_bd; 2. DR InterPro; IPR012677; Nucleotide-bd_a/b_plait. DR InterPro; IPR000504; RRM_dom. DR Pfam; PF00076; RRM_1; 1. DR SMART; SM00360; RRM; 1. DR PROSITE; PS50102; RRM; 1. PE 2: Evidence at transcript level; KW Complete proteome; Reference proteome. SQ SEQUENCE 915 AA; 98738 MW; C1DD905BCFA79C46 CRC64; MPLLQQYDTP DCSGSGGNMR ALSGGSTTEL LQKHSISSYL DHHHQQQQQQ QHHLQLQQHQ QQHSLLERCN DDGLISFIND PITLNDLLGL CGASTANEVV GTGQTPSTSA PILGAGGGGR ANGVTAGAAT ATGVGVGAGG TLPGPGVPSI QGGGGGGVVG QQTNASCNTS AANPSASFGG NGSSSDVNNL LLASAAAAAA AAAGDGAQLS ANAAAYAPLT PSSTHSSASP GTKSNFDYFQ FENVAQSNPL KAFQRTNISF DCSAPLSPST PTSIYNRSFH SSPLVSDSSN SSSGIGLSMD SINMFYNQQQ QQQQPEQQGY TSLGNSMGSG LGLSLANAST RSNSPESQNS SNSTTEQNLL DMINLLSVNS NKIPHQQQQQ QQQQQQQQQQ QQQNQQQLQV QQQHQLQQQF VNLNRNYEQQ ISANLGSQQH GFEHNGVGVG ASSSGNENCF SQYNLENITS VDMELAKLQN LQRINTLKLL HAQAQQMPLI NQLLQSYAGN AIGSVGGSNL GNLMSAGGSS LMTEMAGNVG GIITTNDGHL DRVAKFYKSS AALCDATCTW SGHLPPRSHR MLNYSPKVFL GGIPWDISEQ SLIQIFKPFG SIKVEWPGKE QQAAQPKGYV YIIFESDKQV KALLSACVLQ VDDSHCGRNY FFKISSRRIK SKDVEVIPWI IADSNFVRSS SQKLDPTKTV FVGALHGKLT AEGLGNIMDD LFDGVLYAGI DTDKYKYPIG SGRVTFSNFR SYMKAVSAAF IEIRTTKFTK KVQVDPYLED ALCSICGVQH GPYYCRELSC FRYFCRSCWQ WQHSCDIVKN HKPLTRNSKS QSLVGIGPSS SNVSLPFSGQ RSIRDNRMGN GQHQQHQQHQ YQQQKHRQLQ EYSQPHSLNV MGNSGAANAA ATSMVTLQQR QIHKVRIQRQ QHQAI //