ID Q9VCN7_DROME Unreviewed; 915 AA. AC Q9VCN7; DT 01-MAY-2000, integrated into UniProtKB/TrEMBL. DT 01-MAY-2000, sequence version 1. DT 20-FEB-2007, entry version 40. DE CG10868-PA, isoform A. GN Name=orb; ORFNames=Dmel_CG10868; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=20196006; PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., RA Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., RA Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., RA Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [2] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=22426065; PubMed=12537568; RA Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., RA Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., RA George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., RA Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J., RA Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., RA Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.; RT "Finishing a whole-genome shotgun: release 3 of the Drosophila RT melanogaster euchromatic genome sequence."; RL Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002). RN [3] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=22426071; PubMed=12537574; RA Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., RA Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., RA Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., RA Karpen G.H.; RT "Heterochromatic sequences in a Drosophila whole-genome shotgun RT assembly."; RL Genome Biol. 3:RESEARCH0085.1-RESEARCH0085.16(2002). RN [4] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=22426070; PubMed=12537573; RA Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J.W., Svirskas R., RA Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., RA Ashburner M., Celniker S.E.; RT "The transposable elements of the Drosophila melanogaster euchromatin: RT a genomics perspective."; RL Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002). RN [5] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=22426069; PubMed=12537572; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). RN [6] RP NUCLEOTIDE SEQUENCE. RX PubMed=16110336; DOI=10.1371/journal.pcbi.0010022; RA Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., RA Ashburner M., Anxolabehere D.; RT "Combined evidence annotation of transposable elements in genome RT sequences."; RL PLoS Comput. Biol. 1:166-175(2005). RN [7] RP NUCLEOTIDE SEQUENCE. RG Berkeley Drosophila Genome Project; RA Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R., RA Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E., RA Yu C., Rubin G.; RT "Drosophila melanogaster release 4 sequence."; RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. RN [8] RP NUCLEOTIDE SEQUENCE. RA FlyBase; RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. RN [9] RP NUCLEOTIDE SEQUENCE. RA Celniker S., Carlson J., Kennedy C., Wan K., Frise E., Hoskins R., RA Park S., Svirskas R., Karpen G.; RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE014297; AAF56120.1; -; Genomic_DNA. DR UniGene; Dm.1293; -. DR KEGG; dme:CG10868-PA; -. DR FlyBase; FBgn0004882; orb. DR ArrayExpress; Q9VCN7; -. DR GO; GO:0005737; C:cytoplasm; IDA:FlyBase. DR GO; GO:0003729; F:mRNA binding; TAS:FlyBase. DR GO; GO:0005515; F:protein binding; IPI:FlyBase. DR GO; GO:0000578; P:embryonic axis specification; TAS:FlyBase. DR GO; GO:0048134; P:germ-line cyst formation; TAS:FlyBase. DR GO; GO:0006378; P:mRNA polyadenylation; IMP:FlyBase. DR GO; GO:0048123; P:oocyte dorsal/ventral axis determination (s...; TAS:FlyBase. DR GO; GO:0048123; P:oocyte dorsal/ventral axis determination (s...; IMP:FlyBase. DR GO; GO:0007294; P:oocyte fate determination (sensu the Insect...; TAS:FlyBase. DR GO; GO:0045451; P:pole plasm oskar mRNA localization; TAS:FlyBase. DR GO; GO:0045451; P:pole plasm oskar mRNA localization; NAS:FlyBase. DR GO; GO:0045451; P:pole plasm oskar mRNA localization; IMP:FlyBase. DR GO; GO:0046012; P:positive regulation of oskar mRNA translation; NAS:FlyBase. DR InterPro; IPR012677; a_b_plait_nuc_bd. DR InterPro; IPR000504; RNP1_RNA_bd. DR Gene3D; G3DSA:3.30.70.330; a_b_plait_nuc_bd; 2. DR Pfam; PF00076; RRM_1; 1. DR SMART; SM00360; RRM; 1. DR PROSITE; PS50102; RRM; 1. KW Complete proteome; Nuclear protein. SQ SEQUENCE 915 AA; 98738 MW; C1DD905BCFA79C46 CRC64; MPLLQQYDTP DCSGSGGNMR ALSGGSTTEL LQKHSISSYL DHHHQQQQQQ QHHLQLQQHQ QQHSLLERCN DDGLISFIND PITLNDLLGL CGASTANEVV GTGQTPSTSA PILGAGGGGR ANGVTAGAAT ATGVGVGAGG TLPGPGVPSI QGGGGGGVVG QQTNASCNTS AANPSASFGG NGSSSDVNNL LLASAAAAAA AAAGDGAQLS ANAAAYAPLT PSSTHSSASP GTKSNFDYFQ FENVAQSNPL KAFQRTNISF DCSAPLSPST PTSIYNRSFH SSPLVSDSSN SSSGIGLSMD SINMFYNQQQ QQQQPEQQGY TSLGNSMGSG LGLSLANAST RSNSPESQNS SNSTTEQNLL DMINLLSVNS NKIPHQQQQQ QQQQQQQQQQ QQQNQQQLQV QQQHQLQQQF VNLNRNYEQQ ISANLGSQQH GFEHNGVGVG ASSSGNENCF SQYNLENITS VDMELAKLQN LQRINTLKLL HAQAQQMPLI NQLLQSYAGN AIGSVGGSNL GNLMSAGGSS LMTEMAGNVG GIITTNDGHL DRVAKFYKSS AALCDATCTW SGHLPPRSHR MLNYSPKVFL GGIPWDISEQ SLIQIFKPFG SIKVEWPGKE QQAAQPKGYV YIIFESDKQV KALLSACVLQ VDDSHCGRNY FFKISSRRIK SKDVEVIPWI IADSNFVRSS SQKLDPTKTV FVGALHGKLT AEGLGNIMDD LFDGVLYAGI DTDKYKYPIG SGRVTFSNFR SYMKAVSAAF IEIRTTKFTK KVQVDPYLED ALCSICGVQH GPYYCRELSC FRYFCRSCWQ WQHSCDIVKN HKPLTRNSKS QSLVGIGPSS SNVSLPFSGQ RSIRDNRMGN GQHQQHQQHQ YQQQKHRQLQ EYSQPHSLNV MGNSGAANAA ATSMVTLQQR QIHKVRIQRQ QHQAI //