ID Q9VCB6_DROME Unreviewed; 545 AA. AC Q9VCB6; DT 01-MAY-2000, integrated into UniProtKB/TrEMBL. DT 01-OCT-2002, sequence version 2. DT 05-SEP-2012, entry version 87. DE SubName: Full=AT23187p; DE SubName: Full=Twin, isoform B; GN Name=twin; Synonyms=CCR4, CG5534; ORFNames=CG31137, Dmel_CG31137; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX MEDLINE=20196006; PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., RA Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., RA Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., RA Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [2] RP GENOME REANNOTATION. RC STRAIN=Berkeley; RX MEDLINE=22426069; PubMed=12537572; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). RN [3] RP NUCLEOTIDE SEQUENCE. RA Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., RA Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., RA George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., RA Miranda A., Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., RA Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., RA Celniker S.; RL Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE014297; AAF56256.2; -; Genomic_DNA. DR EMBL; BT001344; AAN71099.1; -; mRNA. DR RefSeq; NP_732967.1; NM_170131.2. DR UniGene; Dm.33521; -. DR ProteinModelPortal; Q9VCB6; -. DR SMR; Q9VCB6; 30-141, 166-530. DR STRING; Q9VCB6; -. DR EnsemblMetazoa; FBtr0084567; FBpp0083952; FBgn0011725. DR GeneID; 42880; -. DR KEGG; dme:Dmel_CG31137; -. DR UCSC; CG31137-RB; d. melanogaster. DR CTD; 42880; -. DR FlyBase; FBgn0011725; twin. DR GeneTree; ENSGT00550000074364; -. DR InParanoid; Q9VCB6; -. DR KO; K12603; -. DR GenomeRNAi; 42880; -. DR NextBio; 831058; -. DR ArrayExpress; Q9VCB6; -. DR Bgee; Q9VCB6; -. DR GO; GO:0030014; C:CCR4-NOT complex; IDA:FlyBase. DR GO; GO:0005737; C:cytoplasm; IDA:FlyBase. DR GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; IMP:FlyBase. DR GO; GO:0048477; P:oogenesis; IMP:FlyBase. DR InterPro; IPR005135; Endo/exonuclease/phosphatase. DR InterPro; IPR001611; Leu-rich_rpt. DR InterPro; IPR025875; Leu-rich_rpt_2_copies. DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp. DR Pfam; PF03372; Exo_endo_phos; 1. DR Pfam; PF12799; LRR_4; 1. DR SMART; SM00369; LRR_TYP; 1. DR SUPFAM; SSF56219; Exo_endo_phos; 1. DR PROSITE; PS51450; LRR; 3. PE 2: Evidence at transcript level; KW Complete proteome; Leucine-rich repeat; Reference proteome; Repeat. SQ SEQUENCE 545 AA; 62383 MW; DDA3CFBF3CF1F259 CRC64; MSRNKDKYDS ANRRQQIFLS QEDIAAGKKT NWSGLEITGC VRNISPSLWE FEHLTALYLN DNQLLRLPAD VGMLTSLRTL DLSSNKLRSL PAELGELIQL RELLLNNNFL RVLPYEIGKL FHLVILGLMG NPLQKEFMNI YNEPNGTQKL LTYMLDNLSF TVNPPPQRPW LPLAKPNKTR PACIFTVMCY NVLCDKYATR QMYGYCPSWA LCWEYRKKSI IDEIRHYAAD IISLQEIETE QFYHFFLPEL KNDGYEGIFS PKSRAKTMSE LERKYVDGCA IFFRASKFTL IKESLIEFNQ LAMANAEGSD NMLNRVMPKD NIGLAALLKV KENAWEPMSE VTQISQPLLV CTAHIHWDPE FCDVKLIQTM MLSNELKTII DEASHSFRPG HKNDSNAVQL LLCGDFNSLP DSGVVEFLGK GRVSMDHLDF KDMGYKSCLQ RLLSNDTNEF THSFKLASAY NEDIMPHTNY TFDFKGIIDY IFYTKTGMVP LGLLGPVSND WLRENKVVGC PHPHIPSDHF PLLVELELMH TASQQAPPNG LINRR //