ID Q9V405_DROME Unreviewed; 413 AA. AC Q9V405; DT 01-MAY-2000, integrated into UniProtKB/TrEMBL. DT 01-MAY-2000, sequence version 1. DT 29-MAY-2013, entry version 117. DE SubName: Full=26S proteasome regulatory complex subunit p48A; DE SubName: Full=CG16916 protein; DE SubName: Full=GH06151p; DE SubName: Full=Rpt3; DE EC=3.6.1.3; GN Name=Rpt3; Synonyms=Rpt3-RA; ORFNames=CG16916, Dmel_CG16916; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Ovary; RA Hoelzl H.; RL Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Ovary; RX PubMed=10893261; DOI=10.1083/jcb.150.1.119; RA Hoelzl H., Kapelari B., Kellermann J., Seemueller E., Suemegi M., RA Udvardy A., Medalia O., Sperling J., Mueller S.A., Engel A., RA Baumeister W.; RT "The regulatory complex of Drosophila melanogaster 26S proteasomes. RT Subunit composition and localization of a deubiquitylating enzyme."; RL J. Cell Biol. 150:119-130(2000). RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., RA Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., RA Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., RA Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [4] RP NUCLEOTIDE SEQUENCE. RX PubMed=12537568; RA Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., RA Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., RA George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., RA Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J., RA Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., RA Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.; RT "Finishing a whole-genome shotgun: release 3 of the Drosophila RT melanogaster euchromatic genome sequence."; RL Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002). RN [5] RP GENOME REANNOTATION. RC STRAIN=Berkeley; RX PubMed=12537572; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfied E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083-RESEARCH0083(2002). RN [6] RP NUCLEOTIDE SEQUENCE. RX PubMed=12537573; RA Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., RA Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., RA Ashburner M., Celniker S.E.; RT "The transposable elements of the Drosophila melanogaster euchromatin: RT a genomics perspective."; RL Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002). RN [7] RP NUCLEOTIDE SEQUENCE. RX PubMed=12537574; RA Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., RA Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., RA Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., RA Karpen G.H.; RT "Heterochromatic sequences in a Drosophila whole-genome shotgun RT assembly."; RL Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002). RN [8] RP NUCLEOTIDE SEQUENCE. RX PubMed=16110336; DOI=10.1371/journal.pcbi.0010022; RA Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., RA Ashburner M., Anxolabehere D.; RT "Combined evidence annotation of transposable elements in genome RT sequences."; RL PLoS Comput. Biol. 1:166-175(2005). RN [9] RP NUCLEOTIDE SEQUENCE. RG Berkeley Drosophila Genome Project; RA Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R., RA Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E., RA Yu C., Rubin G.; RT "Drosophila melanogaster release 4 sequence."; RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. RN [10] RP NUCLEOTIDE SEQUENCE. RA Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S., RA Svirskas R., Rubin G.; RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. RN [11] RP NUCLEOTIDE SEQUENCE. RX PubMed=17569856; DOI=10.1126/science.1139815; RA Smith C.D., Shu S., Mungall C.J., Karpen G.H.; RT "The Release 5.1 annotation of Drosophila melanogaster RT heterochromatin."; RL Science 316:1586-1591(2007). RN [12] RP NUCLEOTIDE SEQUENCE. RX PubMed=17569867; DOI=10.1126/science.1139816; RA Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M., RA Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A., RA Dimitri P., Karpen G.H., Celniker S.E.; RT "Sequence finishing and mapping of Drosophila melanogaster RT heterochromatin."; RL Science 316:1625-1628(2007). RN [13] RP NUCLEOTIDE SEQUENCE. RC STRAIN=Berkeley; RA Carlson J., Booth B., Frise E., Park S., Wan K., Yu C., Celniker S.; RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases. RN [14] RP NUCLEOTIDE SEQUENCE. RG FlyBase; RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases. RN [15] RP NUCLEOTIDE SEQUENCE. RC STRAIN=ZBMEL131, ZBMEL145, ZBMEL157, ZBMEL186, ZBMEL191, ZBMEL229, RC ZBMEL377, ZBMEL398, ZBMEL82, and ZBMEL84; RX PubMed=20150340; DOI=10.1093/molbev/msq046; RA Parsch J., Novozhilov S., Saminadin-Peter S.S., Wong K.M., RA Andolfatto P.; RT "On the utility of short intron sequences as a reference for the RT detection of positive and negative selection in Drosophila."; RL Mol. Biol. Evol. 27:1226-1234(2010). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF145306; AAF08387.1; -; mRNA. DR EMBL; AE014298; AAF48001.1; -; Genomic_DNA. DR EMBL; BT046144; ACI46532.1; -; mRNA. DR EMBL; FN544098; CBA35179.1; -; Genomic_DNA. DR EMBL; FN544099; CBA35180.1; -; Genomic_DNA. DR EMBL; FN544100; CBA35181.1; -; Genomic_DNA. DR EMBL; FN544101; CBA35182.1; -; Genomic_DNA. DR EMBL; FN544102; CBA35183.1; -; Genomic_DNA. DR EMBL; FN544103; CBA35184.1; -; Genomic_DNA. DR EMBL; FN544104; CBA35185.1; -; Genomic_DNA. DR EMBL; FN544105; CBA35186.1; -; Genomic_DNA. DR EMBL; FN544106; CBA35187.1; -; Genomic_DNA. DR EMBL; FN544108; CBA35189.1; -; Genomic_DNA. DR RefSeq; NP_572686.1; NM_132458.2. DR UniGene; Dm.8238; -. DR SMR; Q9V405; 36-413. DR STRING; 7227.FBpp0073292; -. DR EnsemblMetazoa; FBtr0073436; FBpp0073292; FBgn0028686. DR GeneID; 32047; -. DR KEGG; dme:Dmel_CG16916; -. DR UCSC; CG16916-RA; d. melanogaster. DR CTD; 32047; -. DR FlyBase; FBgn0028686; Rpt3. DR eggNOG; COG1222; -. DR GeneTree; ENSGT00550000074962; -. DR InParanoid; Q9V405; -. DR KO; K03063; -. DR OMA; DQTTNVK; -. DR OrthoDB; EOG4P5HRH; -. DR BRENDA; 3.4.25.1; 48. DR GenomeRNAi; 32047; -. DR NextBio; 776548; -. DR GO; GO:0005737; C:cytoplasm; IEA:InterPro. DR GO; GO:0001673; C:male germ cell nucleus; IDA:FlyBase. DR GO; GO:0008540; C:proteasome regulatory particle, base subcomplex; ISS:FlyBase. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0016887; F:ATPase activity; IEA:EC. DR GO; GO:0006200; P:ATP catabolic process; IEA:GOC. DR GO; GO:0030163; P:protein catabolic process; IEA:InterPro. DR GO; GO:0006508; P:proteolysis; IDA:FlyBase. DR GO; GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase. DR InterPro; IPR005937; 26S_Psome_P45. DR InterPro; IPR003593; AAA+_ATPase. DR InterPro; IPR003959; ATPase_AAA_core. DR InterPro; IPR003960; ATPase_AAA_CS. DR InterPro; IPR001270; Chaprnin_ClpA/B. DR InterPro; IPR027417; P-loop_NTPase. DR Pfam; PF00004; AAA; 1. DR PRINTS; PR00300; CLPPROTEASEA. DR SMART; SM00382; AAA; 1. DR SUPFAM; SSF52540; SSF52540; 1. DR TIGRFAMs; TIGR01242; 26Sp45; 1. DR PROSITE; PS00674; AAA; 1. PE 2: Evidence at transcript level; KW ATP-binding; Complete proteome; Hydrolase; Nucleotide-binding; KW Proteasome; Reference proteome. SQ SEQUENCE 413 AA; 46999 MW; 34E7518BE593A0E3 CRC64; MPYNMDVLIP EKDELSDLKL KDAHSSLDEL DMEDLYVRYK KLQKTLEFIE VQEEYIKDEQ RNLKKEYLHA QEEVKRIQSV PLVIGQFLEA VDQNTGIVGS TTGSNYYVRI LSTIDRELLK PSASVALHKH SNALVDVLPP EADSSISMLQ PDEKPDVSYA DIGGMDMQKQ EIREAVELPL THFELYKQIG IDPPRGVLMY GPPGCGKTML AKAVAHHTTA SFIRVVGSEF VQKYLGEGPR MVRDVFRLAK ENAPAIIFID EIDAIATKRF DAQTGADREV QRILLELLNQ MDGFDQTTNV KVIMATNRAD TLDPALLRPG RLDRKIEFPL PDRRQKRLVF STITSKMNLS EDVDLEEFVA RPDKISGADI NAICQEAGMH AVRENRYIVL AKDFEKGYKN NIKKDEQEHE FYK //