ID Q9U1W1_CAEEL Unreviewed; 486 AA. AC Q9U1W1; DT 01-MAY-2000, integrated into UniProtKB/TrEMBL. DT 01-MAY-2000, sequence version 1. DT 17-JUN-2020, entry version 128. DE SubName: Full=PB1 domain-containing protein {ECO:0000313|EMBL:CAB63398.1}; GN Name=tfg-1 {ECO:0000313|EMBL:CAB63398.1, GN ECO:0000313|WormBase:Y63D3A.5}; GN ORFNames=CELE_Y63D3A.5 {ECO:0000313|EMBL:CAB63398.1}, Y63D3A.5 GN {ECO:0000313|WormBase:Y63D3A.5}; OS Caenorhabditis elegans. OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; OC Caenorhabditis. OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CAB63398.1, ECO:0000313|Proteomes:UP000001940}; RN [1] {ECO:0000313|EMBL:CAB63398.1, ECO:0000313|Proteomes:UP000001940} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CAB63398.1, RC ECO:0000313|Proteomes:UP000001940}; RX PubMed=9851916; DOI=10.1126/science.282.5396.2012; RG The C. elegans sequencing consortium; RA Sulson J.E., Waterston R.; RT "Genome sequence of the nematode C. elegans: a platform for investigating RT biology."; RL Science 282:2012-2018(1998). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BX284601; CAB63398.1; -; Genomic_DNA. DR RefSeq; NP_493462.1; NM_061061.5. DR DIP; DIP-26017N; -. DR IntAct; Q9U1W1; 11. DR STRING; 6239.Y63D3A.5.2; -. DR EPD; Q9U1W1; -. DR PaxDb; Q9U1W1; -. DR PeptideAtlas; Q9U1W1; -. DR EnsemblMetazoa; Y63D3A.5.1; Y63D3A.5.1; WBGene00006565. DR EnsemblMetazoa; Y63D3A.5.2; Y63D3A.5.2; WBGene00006565. DR GeneID; 173277; -. DR KEGG; cel:CELE_Y63D3A.5; -. DR UCSC; Y63D3A.5.1; c. elegans. DR CTD; 173277; -. DR WormBase; Y63D3A.5; CE20336; WBGene00006565; tfg-1. DR eggNOG; ENOG410JR8Y; Eukaryota. DR eggNOG; ENOG41101RV; LUCA. DR GeneTree; ENSGT00510000047809; -. DR HOGENOM; CLU_525000_0_0_1; -. DR InParanoid; Q9U1W1; -. DR KO; K09292; -. DR OMA; QPANYNV; -. DR OrthoDB; 1428791at2759; -. DR Reactome; R-CEL-204005; COPII-mediated vesicle transport. DR Proteomes; UP000001940; Chromosome I. DR Bgee; WBGene00006565; Expressed in multi-cellular organism and 4 other tissues. DR GO; GO:0005737; C:cytoplasm; IDA:WormBase. DR GO; GO:0070971; C:endoplasmic reticulum exit site; IDA:WormBase. DR GO; GO:0000139; C:Golgi membrane; IEA:GOC. DR GO; GO:0042802; F:identical protein binding; IEA:InterPro. DR GO; GO:0048208; P:COPII vesicle coating; IEA:InterPro. DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IMP:WormBase. DR GO; GO:0072595; P:maintenance of protein localization in organelle; IMP:WormBase. DR GO; GO:0043066; P:negative regulation of apoptotic process; IMP:WormBase. DR GO; GO:0009306; P:protein secretion; IMP:WormBase. DR GO; GO:0001558; P:regulation of cell growth; IMP:WormBase. DR GO; GO:0008361; P:regulation of cell size; IMP:WormBase. DR GO; GO:0040014; P:regulation of multicellular organism growth; IMP:WormBase. DR InterPro; IPR000270; PB1_dom. DR InterPro; IPR033512; TFG. DR PANTHER; PTHR15335; PTHR15335; 1. DR Pfam; PF00564; PB1; 1. DR SMART; SM00666; PB1; 1. DR PROSITE; PS51745; PB1; 1. PE 1: Evidence at protein level; KW Proteomics identification {ECO:0000213|EPD:Q9U1W1, KW ECO:0000213|PeptideAtlas:Q9U1W1}; KW Reference proteome {ECO:0000313|Proteomes:UP000001940}. FT DOMAIN 10..91 FT /note="PB1" FT /evidence="ECO:0000259|PROSITE:PS51745" FT REGION 197..486 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 207..221 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 223..237 FT /note="Pro-rich" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 249..264 FT /note="Pro-rich" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 265..290 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 291..305 FT /note="Pro-rich" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 308..323 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 327..464 FT /note="Pro-rich" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 486 AA; 49739 MW; A1788AC56E08B98C CRC64; MVHSNGAITS TILKARHADV VRKTSLHHAN DLTLIDLVLN VQRLLALPSD ANFVLKYKDE EGDLVTLAED SDLLLALHTS GATLDVTVVV DSRAREAVHD VQKQVEQIKL DVGKLLGALS ALDVAQIAEQ SNTSVANLSA PKQSHHDNIV FQKSFEAAPP SPVPSEKAEL PATIQPSVHE QFNHRPAHVE EEIPLENHYA PPPHQQIPDD LNTSFSSQPP PPIEQFGAIP PPNATIPSFP TSNAASPPVQ EFAPPPPQQQ QQQFQAPPPP MASHSSISST PVQQQGFAPP QQFGGPPPSG PPSEYGGYAP PQQQQQQFGA PPPQGAPQQG FGAPPQGPPQ GGPPQGSFGA PPPQQFHAPS PQSFGGPPPP VSSAPGNFAP PPQSGPPGAF APPPSAFGAP QGPGGPGGYG PPPPGGPGAP GSYGPPQGGP GGFGPPPPGG PGAYGPPPTG FPPVGAPPPG AAGAPGGNPF ARGPSATGYR QSPYQQ //