ID   Q9U1L3_DROME            Unreviewed;       368 AA.
AC   Q9U1L3;
DT   01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2000, sequence version 1.
DT   24-JUN-2015, entry version 71.
DE   RecName: Full=Translocating chain-associated membrane protein {ECO:0000256|PIRNR:PIRNR005449};
GN   Name=TRAM {ECO:0000313|FlyBase:FBgn0040340};
GN   Synonyms=EG:BACR7A4.5 {ECO:0000313|EMBL:CAB65875.1};
GN   ORFNames=CG11642 {ECO:0000313|FlyBase:FBgn0040340};
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227;
RN   [1] {ECO:0000313|EMBL:CAB65875.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Papagiannakis G., Spanos L., Bolshakov V., Siden-Kiamos I., Louis C.;
RT   "Sequencing the distal X chromosome of Drosophila melanogaster.";
RL   Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CAB65875.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Benos P.;
RL   Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the TRAM family.
CC       {ECO:0000256|PIRNR:PIRNR005449}.
CC   -!- SIMILARITY: Contains TLC (TRAM/LAG1/CLN8) domain.
CC       {ECO:0000256|SAAS:SAAS00153003}.
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DR   EMBL; AL109630; CAB65875.1; -; Genomic_DNA.
DR   IntAct; Q9U1L3; 1.
DR   STRING; 7227.FBpp0070162; -.
DR   PaxDb; Q9U1L3; -.
DR   PRIDE; Q9U1L3; -.
DR   FlyBase; FBgn0040340; TRAM.
DR   eggNOG; COG5058; -.
DR   OrthoDB; EOG7ZPNKC; -.
DR   Reactome; REACT_342983; SRP-dependent cotranslational protein targeting to membrane.
DR   Bgee; Q9U1L3; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005811; C:lipid particle; IDA:FlyBase.
DR   GO; GO:0006909; P:phagocytosis; IMP:FlyBase.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR006634; TLC-dom.
DR   InterPro; IPR013599; TRAM1.
DR   InterPro; IPR016447; Translocation_assoc_membrane.
DR   Pfam; PF08390; TRAM1; 1.
DR   Pfam; PF03798; TRAM_LAG1_CLN8; 1.
DR   PIRSF; PIRSF005449; Translocation_assoc_membrane; 1.
DR   SMART; SM00724; TLC; 1.
DR   PROSITE; PS50922; TLC; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAAS:SAAS00153001};
KW   Protein transport {ECO:0000256|PIRNR:PIRNR005449};
KW   Translocation {ECO:0000256|PIRNR:PIRNR005449};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00152999};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00153000};
KW   Transport {ECO:0000256|PIRNR:PIRNR005449}.
SQ   SEQUENCE   368 AA;  41766 MW;  693795FFFC2ED4A6 CRC64;
     MAIKPGLGRK TSNKNPPILS HEFVIQNHAD IISCVAMVFV VGLMNESTAA FASAFISLHH
     NVSGEDPSRE QPYGKPYTYI AGIKDYCAIF FYTLTCIIMH AIIQEFVLDN ISKKLHLSKF
     KLARFNESGQ LVAFYLLSFV WGAHVLLKEG YLGQVAQLWE GFPDHPMSFL HKFYFVVQLA
     YYLHMLPELY FQKIKTKEEQ QPKIVHSISG FTLIVLAYTL SFQRLALVLL TLHYFSELLS
     HVFQLIGVFD REERLAKLRV VNNAVFFLIR FATSVIGVLT LYYGIGGVRS LLALGGLIAL
     QGYLVFSFIT EQLRAKREAK KEAKREAKLA LQTKKPAKTP KDKVKRKKES DLPEADQTSP
     SPIKQKLK
//