ID Q9TZL8 PRELIMINARY; PRT; 828 AA. AC Q9TZL8; DT 01-MAY-2000 (TrEMBLrel. 13, Created) DT 01-MAY-2000 (TrEMBLrel. 13, Last sequence update) DT 01-MAR-2001 (TrEMBLrel. 16, Last annotation update) DE 6-PHOSPHOFRUCTOKINASE (EC 2.7.1.11) (PHOSPHOFRUCTOKINASE) DE (PHOSPHOHEXOKINASE). GN Y71H10A.1. OS Caenorhabditis elegans. OC Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; OC Rhabditidae; Peloderinae; Caenorhabditis. OX NCBI_TaxID=6239; RN [1] RP SEQUENCE FROM N.A. RC STRAIN=BRISTOL N2; RX MEDLINE=94150718; PubMed=7906398; RA Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., RA Bonfield J., Burton J., Connell M., Copsey T., Cooper J., Coulson A., RA Craxton M., Dear S., Du Z., Durbin R., Favello A., Fulton L., RA Gardner A., Green P., Hawkins T., Hillier L., Jier M., Johnston L., RA Jones M., Kershaw J., Kirsten J., Laister N., Latreille P., RA Lightning J., Lloyd C., McMurray A., Mortimore B., O'Callaghan M., RA Parsons J., Percy C., Rifken L., Roopra A., Saunders D., Shownkeen R., RA Smaldon N., Smith A., Sonnhammer E., Staden R., Sulston J., RA Thierry-Mieg J., Thomas K., Vaudin M., Vaughan K., Waterston R., RA Watson A., Weinstock L., Wilkinson-Sproat J., Wohldman P.; RT "2.2 Mb of contiguous nucleotide sequence from chromosome III of C. RT elegans."; RL Nature 368:32-38(1994). RN [2] RP SEQUENCE FROM N.A. RC STRAIN=BRISTOL N2; RA Antonio B., Geisel C., Smith A., Angell S.; RT "The sequence of C. elegans cosmid Y71H10A."; RL Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases. RN [3] RP SEQUENCE FROM N.A. RC STRAIN=BRISTOL N2; RA Waterston R.; RL Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: ATP + D-FRUCTOSE 6-PHOSPHATE = ADP + D- CC FRUCTOSE 1,6-BISPHOSPHATE (BY SIMILARITY). CC -!- PATHWAY: KEY CONTROL STEP OF GLYCOLYSIS (BY SIMILARITY). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF098505; AAC67416.1; -. DR HSSP; P00512; 3PFK. DR InterPro; IPR000023; -. DR Pfam; PF00365; PFK; 2. DR PRINTS; PR00476; PHFRCTKINASE. DR PROSITE; PS00433; PHOSPHOFRUCTOKINASE; 2. KW Glycolysis; Kinase; Transferase. SQ SEQUENCE 828 AA; 91275 MW; 14AD8735391FD84C CRC64; MDADASTITP EELDFIRQRA LRRFDSIVPT AGREGTEIAS DIFKGRTLAI YTSGGDSQGM NSAVRSITRM AIYCGCKVYL IYEGYEGMIE GGDFIKEATW NTVSDIIQQG GTIIGSARSS EFRTREGRLK AATNLINRGI GRLVCIGGDG SLTGANTFRL EWTDLVQELV KNQRVTAAAA KKIPYIQIVG LVGSIDNDFC GTDMTIGTDS ALQRIISSID AVVATAQSHQ RAFVIEVMGR HCGYLALVAA LASEADFCFI PEWPAPENWR DVLCDKLSQM RSEGQRLNII IVAEGAIDRD GKAITAEDVK TAVKEKLKYD TRVTILGHVQ RGGAPSAFDR LLGCRMGAEA VFALMEMTEV SGIFCEFFIN GLNESEPCVI SIDGNVMVRV PLLKCVERTQ MVQKAMADKD WTTAVMLRGR SFQRNLETYK LLTKMRTVEK DNLSEGHKFN VAVINVGAPA GGMNAAVRSY VRMALYHQCT VYGIEDSFEG LANGSFKQFK WSDVTNWAMN GGSFLGTQKS LPTEKTMPQL AAQLKKHNIQ ALLLVGGFEA YHSTIILAEN REKYPEFCIP MCVIPCTISN NVPGTMVSLG SDTAINEICQ MIDKIKQSAT GTKRRVFIVE TMGGYCGYLA TLSALSSGAD NAYIFEEPFT VQDLSDDVDV ILSKMEVGAK RYLVVRNEWA DKNLTTDFVQ NLFDSEGKKN FTTRVNVLGH VQQGGSPTPF DRNMGTKLAA RALEFLLIQL KENLTADNKV IAKSAHTATL LGLKGRKVVF TPVQDLKKET DFEHRLPSEQ WWMALRPLLR VLARHRSTVE SSAILESVEE ESADSHMF //