ID PAN_ARATH Reviewed; 452 AA. AC Q9SX27; Q9ZPJ6; DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot. DT 01-MAY-2000, sequence version 1. DT 29-APR-2015, entry version 95. DE RecName: Full=Transcription factor PERIANTHIA; DE AltName: Full=bZIP transcription factor 46; DE Short=AtbZIP46; GN Name=PAN; OrderedLocusNames=At1g68640; ORFNames=F24J5.12; OS Arabidopsis thaliana (Mouse-ear cress). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; OC Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; OC Arabidopsis. OX NCBI_TaxID=3702; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], DEVELOPMENTAL STAGE, FUNCTION, AND RP DISRUPTION PHENOTYPE. RX PubMed=9990857; DOI=10.1101/gad.13.3.334; RA Chuang C.F., Running M.P., Williams R.W., Meyerowitz E.M.; RT "The PERIANTHIA gene encodes a bZIP protein involved in the RT determination of floral organ number in Arabidopsis thaliana."; RL Genes Dev. 13:334-344(1999). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Columbia; RX PubMed=11130712; DOI=10.1038/35048500; RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., RA White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., RA Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., RA Chung M.K., Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., RA Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., RA Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., RA Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., RA Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., RA Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., RA Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., RA Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., RA Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., RA Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., RA Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., RA Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.; RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis RT thaliana."; RL Nature 408:816-820(2000). RN [3] RP GENOME REANNOTATION. RC STRAIN=cv. Columbia; RG The Arabidopsis Information Resource (TAIR); RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases. RN [4] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=cv. Columbia; RX PubMed=11910074; DOI=10.1126/science.1071006; RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T., RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., RA Hayashizaki Y., Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., RA Shibata K., Shinagawa A., Shinozaki K.; RT "Functional annotation of a full-length Arabidopsis cDNA collection."; RL Science 296:141-145(2002). RN [5] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=cv. Columbia; RX PubMed=14593172; DOI=10.1126/science.1088305; RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., RA Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., RA Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., RA Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., RA Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., RA Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., RA Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., RA Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., RA Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., RA Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., RA Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., RA Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.; RT "Empirical analysis of transcriptional activity in the Arabidopsis RT genome."; RL Science 302:842-846(2003). RN [6] RP DISRUPTION PHENOTYPE. RX PubMed=8620853; RA Running M.P., Meyerowitz E.M.; RT "Mutations in the PERIANTHIA gene of Arabidopsis specifically alter RT floral organ number and initiation pattern."; RL Development 122:1261-1269(1996). RN [7] RP GENE FAMILY, AND NOMENCLATURE. RX PubMed=11906833; DOI=10.1016/S1360-1385(01)02223-3; RA Jakoby M., Weisshaar B., Droege-Laser W., Vicente-Carbajosa J., RA Tiedemann J., Kroj T., Parcy F.; RT "bZIP transcription factors in Arabidopsis."; RL Trends Plant Sci. 7:106-111(2002). RN [8] RP INTERACTION WITH BOP1 AND BOP2. RX PubMed=15805484; DOI=10.1105/tpc.104.030536; RA Hepworth S.R., Zhang Y., McKim S., Li X., Haughn G.W.; RT "BLADE-ON-PETIOLE-dependent signaling controls leaf and floral RT patterning in Arabidopsis."; RL Plant Cell 17:1434-1448(2005). RN [9] RP FUNCTION. RX PubMed=19395638; DOI=10.1242/dev.035436; RA Das P., Ito T., Wellmer F., Vernoux T., Dedieu A., Traas J., RA Meyerowitz E.M.; RT "Floral stem cell termination involves the direct regulation of RT AGAMOUS by PERIANTHIA."; RL Development 136:1605-1611(2009). RN [10] RP FUNCTION. RX PubMed=19395639; DOI=10.1242/dev.033647; RA Maier A.T., Stehling-Sun S., Wollmann H., Demar M., Hong R.L., RA Haubeiss S., Weigel D., Lohmann J.U.; RT "Dual roles of the bZIP transcription factor PERIANTHIA in the control RT of floral architecture and homeotic gene expression."; RL Development 136:1613-1620(2009). RN [11] RP INTERACTION WITH GRXC7/ROXY1, AND MUTAGENESIS OF CYS-340. RX PubMed=19218396; DOI=10.1105/tpc.108.064477; RA Li S., Lauri A., Ziemann M., Busch A., Bhave M., Zachgo S.; RT "Nuclear activity of ROXY1, a glutaredoxin interacting with TGA RT factors, is required for petal development in Arabidopsis thaliana."; RL Plant Cell 21:429-441(2009). CC -!- FUNCTION: Transcriptional activator involved in the determination CC of floral organ number. Acts to determine floral organ patterning CC by establishing floral organ primordia in specific numbers and CC positions. Plays a role in regulating stem cell fate by directly CC controlling AG expression. Binds to the 5'-AAGAAT-3' cis-acting CC element found in AG promoter. Might represent a target for a post- CC translational modification by GRXC7/ROXY1. CC {ECO:0000269|PubMed:19395638, ECO:0000269|PubMed:19395639, CC ECO:0000269|PubMed:9990857}. CC -!- SUBUNIT: Interacts with GRXC7/ROXY1. Interacts with BOP1 and BOP2. CC {ECO:0000269|PubMed:15805484, ECO:0000269|PubMed:19218396}. CC -!- INTERACTION: CC Q96305:GRXC7; NbExp=3; IntAct=EBI-2257975, EBI-2257898; CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE- CC ProRule:PRU00978}. CC -!- DEVELOPMENTAL STAGE: Expressed in the apical meristem, the floral CC meristem, each whorl of organ primordia, and in ovule primordia CC during wild-type flower development. {ECO:0000269|PubMed:9990857}. CC -!- DISRUPTION PHENOTYPE: Mutant plants have extra floral organs. The CC modal numbers of organs in mutant flowers are 5 sepals, 5 petals, CC 5 stamens, and 2 carpels in contrast with the tetramerous pattern CC of the wild type. {ECO:0000269|PubMed:8620853, CC ECO:0000269|PubMed:9990857}. CC -!- SIMILARITY: Belongs to the bZIP family. {ECO:0000305}. CC -!- SIMILARITY: Contains 1 bZIP (basic-leucine zipper) domain. CC {ECO:0000255|PROSITE-ProRule:PRU00978}. CC -!- SEQUENCE CAUTION: CC Sequence=AAD19660.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF111711; AAD19660.1; ALT_SEQ; Genomic_DNA. DR EMBL; AC008075; AAD49979.1; -; Genomic_DNA. DR EMBL; CP002684; AEE34822.1; -; Genomic_DNA. DR EMBL; AK118286; BAC42904.1; -; mRNA. DR EMBL; BT008586; AAP40413.1; -; mRNA. DR PIR; H96710; H96710. DR RefSeq; NP_177031.1; NM_105536.3. DR UniGene; At.35500; -. DR UniGene; At.50012; -. DR ProteinModelPortal; Q9SX27; -. DR BioGrid; 28415; 1. DR IntAct; Q9SX27; 1. DR STRING; 3702.AT1G68640.1-P; -. DR PRIDE; Q9SX27; -. DR EnsemblPlants; AT1G68640.1; AT1G68640.1; AT1G68640. DR GeneID; 843194; -. DR KEGG; ath:AT1G68640; -. DR TAIR; AT1G68640; -. DR eggNOG; NOG278920; -. DR HOGENOM; HOG000116597; -. DR InParanoid; Q9SX27; -. DR KO; K14431; -. DR OMA; AVMSHYD; -. DR PhylomeDB; Q9SX27; -. DR PRO; PR:Q9SX27; -. DR Proteomes; UP000006548; Chromosome 1. DR Genevestigator; Q9SX27; -. DR GO; GO:0005634; C:nucleus; IDA:TAIR. DR GO; GO:0003677; F:DNA binding; IPI:TAIR. DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro. DR GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:TAIR. DR GO; GO:0009909; P:regulation of flower development; IMP:TAIR. DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW. DR InterPro; IPR004827; bZIP. DR InterPro; IPR025422; TGA_domain. DR Pfam; PF00170; bZIP_1; 1. DR Pfam; PF14144; DOG1; 1. DR SMART; SM00338; BRLZ; 1. DR PROSITE; PS50217; BZIP; 1. DR PROSITE; PS00036; BZIP_BASIC; 1. PE 1: Evidence at protein level; KW Activator; Coiled coil; Complete proteome; DNA-binding; Nucleus; KW Reference proteome; Transcription; Transcription regulation. FT CHAIN 1 452 Transcription factor PERIANTHIA. FT /FTId=PRO_0000398152. FT DOMAIN 164 227 bZIP. {ECO:0000255|PROSITE- FT ProRule:PRU00978}. FT REGION 166 186 Basic motif. {ECO:0000255|PROSITE- FT ProRule:PRU00978}. FT REGION 192 206 Leucine-zipper. {ECO:0000255|PROSITE- FT ProRule:PRU00978}. FT COMPBIAS 69 75 Poly-Gly. FT MUTAGEN 340 340 C->A: Abolishes function in flower FT development. FT {ECO:0000269|PubMed:19218396}. SQ SEQUENCE 452 AA; 50458 MW; 06CE2D1837AC261C CRC64; MQSSFKTVPF TPDFYSQSSY FFRGDSCLEE FHQPVNGFHH EEAIDLSPNV TIASANLHYT TFDTVMDCGG GGGGGLRERL EGGEEECLDT GQLVYQKGTR LVGGGVGEVN SSWCDSVSAM ADNSQHTDTS TDIDTDDKTQ LNGGHQGMLL ATNCSDQSNV KSSDQRTLRR LAQNREAARK SRLRKKAYVQ QLENSRIRLA QLEEELKRAR QQGSLVERGV SADHTHLAAG NGVFSFELEY TRWKEEHQRM INDLRSGVNS QLGDNDLRVL VDAVMSHYDE IFRLKGIGTK VDVFHMLSGM WKTPAERFFM WLGGFRSSEL LKILGNHVDP LTDQQLIGIC NLQQSSQQAE DALSQGMEAL QQSLLETLSS ASMGPNSSAN VADYMGHMAM AMGKLGTLEN FLRQADLLRQ QTLQQLHRIL TTRQAARAFL VIHDYISRLR ALSSLWLARP RD //