ID METN_SALEN Reviewed; 315 AA. AC Q9S4Z0; DT 09-JAN-2007, integrated into UniProtKB/Swiss-Prot. DT 01-MAY-2000, sequence version 1. DT 23-FEB-2022, entry version 92. DE RecName: Full=Methionine import ATP-binding protein MetN {ECO:0000255|HAMAP-Rule:MF_01719}; DE EC=7.4.2.11 {ECO:0000255|HAMAP-Rule:MF_01719}; GN Name=metN {ECO:0000255|HAMAP-Rule:MF_01719}; Synonyms=sfbB; OS Salmonella enteritidis. OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; OC Enterobacteriaceae; Salmonella. OX NCBI_TaxID=149539; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=S1400; RX PubMed=10447888; DOI=10.1046/j.1365-2958.1999.01526.x; RA Pattery T., Hernalsteens J.-P., De Greve H.; RT "Identification and molecular characterization of a novel Salmonella RT enteritidis pathogenicity islet encoding an ABC transporter."; RL Mol. Microbiol. 33:791-805(1999). CC -!- FUNCTION: Part of the ABC transporter complex MetNIQ involved in CC methionine import. Responsible for energy coupling to the transport CC system. {ECO:0000255|HAMAP-Rule:MF_01719}. CC -!- CATALYTIC ACTIVITY: CC Reaction=ATP + H2O + L-methionine(out) = ADP + H(+) + L-methionine(in) CC + phosphate; Xref=Rhea:RHEA:29779, ChEBI:CHEBI:15377, CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, CC ChEBI:CHEBI:57844, ChEBI:CHEBI:456216; EC=7.4.2.11; CC Evidence={ECO:0000255|HAMAP-Rule:MF_01719}; CC -!- CATALYTIC ACTIVITY: CC Reaction=ATP + D-methionine(out) + H2O = ADP + D-methionine(in) + H(+) CC + phosphate; Xref=Rhea:RHEA:29767, ChEBI:CHEBI:15377, CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, CC ChEBI:CHEBI:57932, ChEBI:CHEBI:456216; EC=7.4.2.11; CC Evidence={ECO:0000255|HAMAP-Rule:MF_01719}; CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (MetN), CC two transmembrane proteins (MetI) and a solute-binding protein (MetQ). CC {ECO:0000255|HAMAP-Rule:MF_01719}. CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP- CC Rule:MF_01719}; Peripheral membrane protein {ECO:0000255|HAMAP- CC Rule:MF_01719}. CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Methionine CC importer (TC 3.A.1.24) family. {ECO:0000255|HAMAP-Rule:MF_01719}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF102556; AAD51880.1; -; Genomic_DNA. DR SMR; Q9S4Z0; -. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0033232; F:ABC-type D-methionine transporter activity; IEA:UniProtKB-EC. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR Gene3D; 3.40.50.300; -; 1. DR InterPro; IPR003593; AAA+_ATPase. DR InterPro; IPR026253; ABC_MetN. DR InterPro; IPR003439; ABC_transporter-like_ATP-bd. DR InterPro; IPR017871; ABC_transporter-like_CS. DR InterPro; IPR045865; ACT-like_dom_sf. DR InterPro; IPR018449; NIL_domain. DR InterPro; IPR027417; P-loop_NTPase. DR PANTHER; PTHR43166:SF5; PTHR43166:SF5; 1. DR Pfam; PF00005; ABC_tran; 1. DR Pfam; PF09383; NIL; 1. DR SMART; SM00382; AAA; 1. DR SMART; SM00930; NIL; 1. DR SUPFAM; SSF52540; SSF52540; 1. DR SUPFAM; SSF55021; SSF55021; 1. DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1. DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1. DR PROSITE; PS51264; METN; 1. PE 3: Inferred from homology; KW Amino-acid transport; ATP-binding; Cell inner membrane; Cell membrane; KW Membrane; Nucleotide-binding; Translocase; Transport. FT CHAIN 1..315 FT /note="Methionine import ATP-binding protein MetN" FT /id="PRO_0000270377" FT DOMAIN 2..219 FT /note="ABC transporter" FT /evidence="ECO:0000255|HAMAP-Rule:MF_01719" FT NP_BIND 16..23 FT /note="ATP" FT /evidence="ECO:0000255|HAMAP-Rule:MF_01719" SQ SEQUENCE 315 AA; 34141 MW; 89D8C257EE5757BF CRC64; MIEIEKVCVD FTAGRGTSGA GKSTLLRTLN ALTRPSQGRV NVNGVEISAL DGKALRQARQ RIGMIFQHFN LMHTRTVAQN VAFSLKAAGW ERSKIAPRVA EILTLVGLAD KANRFPVQLS GGQKQRVGIA RAIANHPDVL LCDEPTSALD LETSATILAL LRQINAQLGI TIVLITHEMN VIKSICDRVA VMSGGKVVES GEVFDEFAHP QHAFTQQLVS HTLNLTLPER LREHLPGQLL KILFIGDSAE QPVLSEVAIK FGVAVNILHG KIEYIGERAL GILVVQLTAP HNPTAVAAAV EHIRQRTAQV EVIRG //