ID URE23_DEIRA Reviewed; 228 AA. AC Q9RYJ3; DT 16-JAN-2004, integrated into UniProtKB/Swiss-Prot. DT 01-MAY-2000, sequence version 1. DT 03-OCT-2012, entry version 79. DE RecName: Full=Urease subunit gamma/beta; DE EC=3.5.1.5; DE AltName: Full=Urea amidohydrolase subunit gamma/beta; GN Name=ureAB; OrderedLocusNames=DR_A0319; OS Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / OS LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422). OC Bacteria; Deinococcus-Thermus; Deinococci; Deinococcales; OC Deinococcaceae; Deinococcus. OX NCBI_TaxID=243230; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / RC NCIMB 9279 / R1 / VKM B-1422; RX MEDLINE=20036896; PubMed=10567266; DOI=10.1126/science.286.5444.1571; RA White O., Eisen J.A., Heidelberg J.F., Hickey E.K., Peterson J.D., RA Dodson R.J., Haft D.H., Gwinn M.L., Nelson W.C., Richardson D.L., RA Moffat K.S., Qin H., Jiang L., Pamphile W., Crosby M., Shen M., RA Vamathevan J.J., Lam P., McDonald L.A., Utterback T.R., Zalewski C., RA Makarova K.S., Aravind L., Daly M.J., Minton K.W., Fleischmann R.D., RA Ketchum K.A., Nelson K.E., Salzberg S.L., Smith H.O., Venter J.C., RA Fraser C.M.; RT "Genome sequence of the radioresistant bacterium Deinococcus RT radiodurans R1."; RL Science 286:1571-1577(1999). CC -!- CATALYTIC ACTIVITY: Urea + H(2)O = CO(2) + 2 NH(3). CC -!- PATHWAY: Nitrogen metabolism; urea degradation; CO(2) and NH(3) CC from urea (urease route): step 1/1. CC -!- SUBUNIT: Heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) CC subunits (By similarity). CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity). CC -!- SIMILARITY: In the N-terminal section; belongs to the urease gamma CC subunit family. CC -!- SIMILARITY: In the C-terminal section; belongs to the urease beta CC subunit family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE001825; AAF12460.1; -; Genomic_DNA. DR PIR; D75586; D75586. DR RefSeq; NP_285642.1; NC_001264.1. DR ProteinModelPortal; Q9RYJ3; -. DR SMR; Q9RYJ3; 1-228. DR GeneID; 1798075; -. DR GenomeReviews; AE001825_GR; DR_A0319. DR KEGG; dra:DR_A0319; -. DR PATRIC; 21633680; VBIDeiRad64572_3209. DR eggNOG; COG0832; -. DR HOGENOM; HOG000075053; -. DR KO; K14048; -. DR OMA; SSVRFGP; -. DR ProtClustDB; PRK13192; -. DR BioCyc; DRAD243230:DR_A0319-MONOMER; -. DR UniPathway; UPA00258; UER00370. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0009039; F:urease activity; IEA:EC. DR GO; GO:0043419; P:urea catabolic process; IEA:UniProtKB-UniPathway. DR Gene3D; G3DSA:2.10.150.10; Urease_beta; 1. DR Gene3D; G3DSA:3.30.280.10; Urease_gamma_reg; 1. DR HAMAP; MF_01955; Urease_beta_gamma; 1; -. DR InterPro; IPR002019; Urease_beta. DR InterPro; IPR008223; Urease_gamma-beta_su. DR InterPro; IPR002026; Urease_gamma/gamma-beta_su. DR InterPro; IPR012010; Urease_gamma_su. DR Pfam; PF00699; Urease_beta; 1. DR Pfam; PF00547; Urease_gamma; 1. DR PIRSF; PIRSF001225; Urease_gammabeta; 1. DR ProDom; PD002319; Urease_gamma_reg; 1. DR SUPFAM; SSF51278; Urease_beta; 1. DR SUPFAM; SSF54111; Urease_gamma_reg; 1. DR TIGRFAMs; TIGR00192; urease_beta; 1. DR TIGRFAMs; TIGR00193; urease_gam; 1. PE 3: Inferred from homology; KW Complete proteome; Cytoplasm; Hydrolase; Reference proteome. FT CHAIN 1 228 Urease subunit gamma/beta. FT /FTId=PRO_0000098076. FT REGION 1 101 Urease gamma. FT REGION 102 228 Urease beta. SQ SEQUENCE 228 AA; 24521 MW; 257CCEA909C8D0A2 CRC64; MQLTERERDK LLIFTAAQLA RERRARGLKL NHPEAVALIT AEVLEGIRDG RRVEDLMSFG AAILTPDDVL DGVPELIHEI QVEGTFPDGT KLVTVHDPIR GAASRRVAGE YLLEGGEIEL NAGRPVTTLT VANTADRPVQ VGSHFHFFEV NAGLRFDRAA AYGFRLNIPA GTAVRFEPGE EREVDLVPLG GSRTVYGMNA LVNGDLDAPG TREAALEGAR AAGFGGAQ //