ID URE23_DEIRA Reviewed; 228 AA. AC Q9RYJ3; DT 16-JAN-2004, integrated into UniProtKB/Swiss-Prot. DT 01-MAY-2000, sequence version 1. DT 06-FEB-2007, entry version 39. DE Urease gamma/subunit beta (EC 3.5.1.5) (Urea amidohydrolase gamma/beta DE subunit). GN Name=ureAB; OrderedLocusNames=DR_A0319; OS Deinococcus radiodurans. OC Bacteria; Deinococcus-Thermus; Deinococci; Deinococcales; OC Deinococcaceae; Deinococcus. OX NCBI_TaxID=1299; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 13939 / DSM 20539 / IFO 15346 / LMG 4051 / NCIB 9279 / R1; RX MEDLINE=20036896; PubMed=10567266; DOI=10.1126/science.286.5444.1571; RA White O., Eisen J.A., Heidelberg J.F., Hickey E.K., Peterson J.D., RA Dodson R.J., Haft D.H., Gwinn M.L., Nelson W.C., Richardson D.L., RA Moffat K.S., Qin H., Jiang L., Pamphile W., Crosby M., Shen M., RA Vamathevan J.J., Lam P., McDonald L.A., Utterback T.R., Zalewski C., RA Makarova K.S., Aravind L., Daly M.J., Minton K.W., Fleischmann R.D., RA Ketchum K.A., Nelson K.E., Salzberg S.L., Smith H.O., Venter J.C., RA Fraser C.M.; RT "Genome sequence of the radioresistant bacterium Deinococcus RT radiodurans R1."; RL Science 286:1571-1577(1999). CC -!- CATALYTIC ACTIVITY: Urea + H(2)O = CO(2) + 2 NH(3). CC -!- PATHWAY: Nitrogen metabolism; urea degradation; CO(2) and NH(3) CC from urea (urease route): single step [final step]. CC -!- SUBUNIT: Heterohexamer of 3 ureC (alpha) and 3 ureAB (gamma/beta) CC subunits (By similarity). CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity). CC -!- SIMILARITY: In the N-terminal section; belongs to the urease gamma CC subunit family. CC -!- SIMILARITY: In the C-terminal section; belongs to the urease beta CC subunit family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE001825; AAF12460.1; -; Genomic_DNA. DR HSSP; P18316; 1EJX. DR GenomeReviews; AE001825_GR; DR_A0319. DR KEGG; dra:DRA0319; -. DR TIGR; DR_A0319; -. DR GO; GO:0019627; P:urea metabolic process; IEA:HAMAP. DR HAMAP; MF_01955; -; 1. DR InterPro; IPR002019; Urease_beta. DR InterPro; IPR002026; Urease_gamma_reg. DR InterPro; IPR008223; Urease_gammabeta. DR Gene3D; G3DSA:2.10.150.10; Urease_beta; 1. DR Pfam; PF00699; Urease_beta; 1. DR Pfam; PF00547; Urease_gamma; 1. DR PIRSF; PIRSF001225; Urease_gammabeta; 1. DR ProDom; PD002326; Urease_beta; 1. DR ProDom; PD002319; Urease_gamma; 1. DR TIGRFAMs; TIGR00192; urease_beta; 1. DR TIGRFAMs; TIGR00193; urease_gam; 1. KW Complete proteome; Hydrolase. FT CHAIN 1 228 Urease gamma/subunit beta. FT /FTId=PRO_0000098076. FT REGION 1 101 Urease gamma. FT REGION 102 228 Urease beta. SQ SEQUENCE 228 AA; 24521 MW; 257CCEA909C8D0A2 CRC64; MQLTERERDK LLIFTAAQLA RERRARGLKL NHPEAVALIT AEVLEGIRDG RRVEDLMSFG AAILTPDDVL DGVPELIHEI QVEGTFPDGT KLVTVHDPIR GAASRRVAGE YLLEGGEIEL NAGRPVTTLT VANTADRPVQ VGSHFHFFEV NAGLRFDRAA AYGFRLNIPA GTAVRFEPGE EREVDLVPLG GSRTVYGMNA LVNGDLDAPG TREAALEGAR AAGFGGAQ //