ID Q9R0T7 PRELIMINARY; PRT; 246 AA. AC Q9R0T7; DT 01-MAY-2000 (TrEMBLrel. 13, Created) DT 01-MAY-2000 (TrEMBLrel. 13, Last sequence update) DT 01-JUN-2002 (TrEMBLrel. 21, Last annotation update) DE Pancreatic trypsin (0910001B19RIK protein) (Trypsinogen 8). GN TD OR 0910001B19RIK OR TRYPSINOGEN. OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Mus. OX NCBI_TaxID=10090; RN [1] RP SEQUENCE FROM N.A. RC STRAIN=129SVJ; RX MEDLINE=99436155; PubMed=10506205; RA Ohmura K., Kohno N., Kobayashi Y., Yamagata K., Sato S., RA Kashiwabara S., Baba T.; RT "A homologue of pancreatic trypsin is localized in the acrosome of RT mammalian sperm and is released during acrosome reaction."; RL J. Biol. Chem. 274:29426-29432(1999). RN [2] RP SEQUENCE FROM N.A. RC STRAIN=C57BL/6J; TISSUE=STOMACH, AND SPLEEN; RX MEDLINE=21085660; PubMed=11217851; RA Kawai J., Shinagawa A., Shibata K., Yoshino M., Itoh M., Ishii Y., RA Arakawa T., Hara A., Fukunishi Y., Konno H., Adachi J., Fukuda S., RA Aizawa K., Izawa M., Nishi K., Kiyosawa H., Kondo S., Yamanaka I., RA Saito T., Okazaki Y., Gojobori T., Bono H., Kasukawa T., Saito R., RA Kadota K., Matsuda H.A., Ashburner M., Batalov S., Casavant T., RA Fleischmann W., Gaasterland T., Gissi C., King B., Kochiwa H., RA Kuehl P., Lewis S., Matsuo Y., Nikaido I., Pesole G., Quackenbush J., RA Schriml L.M., Staubli F., Suzuki R., Tomita M., Wagner L., Washio T., RA Sakai K., Okido T., Furuno M., Aono H., Baldarelli R., Barsh G., RA Blake J., Boffelli D., Bojunga N., Carninci P., de Bonaldo M.F., RA Brownstein M.J., Bult C., Fletcher C., Fujita M., Gariboldi M., RA Gustincich S., Hill D., Hofmann M., Hume D.A., Kamiya M., Lee N.H., RA Lyons P., Marchionni L., Mashima J., Mazzarelli J., Mombaerts P., RA Nordone P., Ring B., Ringwald M., Rodriguez I., Sakamoto N., RA Sasaki H., Sato K., Schoenbach C., Seya T., Shibata Y., Storch K.-F., RA Suzuki H., Toyo-oka K., Wang K.H., Weitz C., Whittaker C., Wilming L., RA Wynshaw-Boris A., Yoshida K., Hasegawa Y., Kawaji H., Kohtsuki S., RA Hayashizaki Y.; RT "Functional annotation of a full-length mouse cDNA collection."; RL Nature 409:685-690(2001). RN [3] RP SEQUENCE FROM N.A. RC STRAIN=129; RX MEDLINE=21103195; PubMed=11160223; RA Chen F., Rowen L., Hood L., Rothenberg E.V.; RT "Differential transcriptional regulation of individual TCR Vbeta RT segments before gene rearrangement."; RL J. Immunol. 166:1771-1780(2001). CC -!- SIMILARITY: BELONGS TO PEPTIDASE FAMILY S1; ALSO KNOWN AS THE CC TRYPSIN FAMILY. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB017032; BAA74761.1; -. DR EMBL; AK008667; BAB25821.1; -. DR EMBL; AK003064; BAB22542.1; -. DR EMBL; AE000664; AAB69056.1; -. DR HSSP; P00763; 1SLU. DR MEROPS; S01.057; -. DR MGD; MGI:1913350; 0910001B19Rik. DR InterPro; IPR001314; Chymotrypsin. DR InterPro; IPR001254; Ser_protease_Try. DR Pfam; PF00089; trypsin; 1. DR PRINTS; PR00722; CHYMOTRYPSIN. DR SMART; SM00020; Tryp_SPc; 1. DR PROSITE; PS50240; TRYPSIN_DOM; 1. DR PROSITE; PS00134; TRYPSIN_HIS; UNKNOWN_1. DR PROSITE; PS00135; TRYPSIN_SER; 1. KW Hydrolase; Serine protease. SQ SEQUENCE 246 AA; 26274 MW; B6A9F4C99079633F CRC64; MRALLFLALV GAAVAFPVDD DDKIVGGYTC RENSVPYQVS LNSGYHFCGG SLINDQWVVS AAHCYKSRIQ VRLGEHNINV LEGNEQFVNS AKIIKHPNFN SRTLNNDIML IKLASPVTLN ARVATVALPS SCAPAGTQCL ISGWGNTLSF GVNNPDLLQC LDAPLLPQAD CEASYPGKIT NNMICVGFLE GGKDSCQGDS GGPVVCNGQL QGIVSWGYGC ALKDNPGVYT KVCNYVDWIQ NTIAAN //