ID PKP3_MOUSE STANDARD; PRT; 797 AA. AC Q9QY23; DT 28-FEB-2003 (Rel. 41, Created) DT 28-FEB-2003 (Rel. 41, Last sequence update) DT 24-JAN-2006 (Rel. 49, Last annotation update) DE Plakophilin-3. GN Name=Pkp3; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA]. RX MEDLINE=99310799; PubMed=10381383; RA Bonne S., van Hengel J., Nollet F., Kools P., van Roy F.; RT "Plakophilin-3, a novel armadillo-like protein present in nuclei and RT desmosomes of epithelial cells."; RL J. Cell Sci. 112:2265-2276(1999). CC -!- FUNCTION: May play a role in junctional plaques. CC -!- SUBCELLULAR LOCATION: Nuclear and associated with desmosomes. CC -!- SIMILARITY: Belongs to the beta-catenin family. CC -!- SIMILARITY: Contains 8 ARM repeats. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF136719; AAD55892.1; -; mRNA. DR Ensembl; ENSMUSG00000054065; Mus musculus. DR MGI; MGI:1891830; Pkp3. DR GO; GO:0030057; C:desmosome; IDA. DR InterPro; IPR011989; ARM-like. DR InterPro; IPR000225; Armadillo. DR Pfam; PF00514; Arm; 2. DR SMART; SM00185; ARM; 2. DR PROSITE; PS50176; ARM_REPEAT; 1. KW Cell adhesion; Cytoskeleton; Nuclear protein; Repeat; KW Structural protein. FT REPEAT 305 348 ARM 1. FT REPEAT 351 390 ARM 2. FT REPEAT 393 432 ARM 3. FT REPEAT 449 487 ARM 4. FT REPEAT 491 536 ARM 5. FT REPEAT 596 637 ARM 6. FT REPEAT 645 684 ARM 7. FT REPEAT 689 730 ARM 8. SQ SEQUENCE 797 AA; 87299 MW; A9DD80A76C79C126 CRC64; MQEGNFLLSA LQPETGVCSL ALPSDLQLDR RGAEGPEADR LRAARVQEQV RARLLQLGQQ SRHNGSAELD GSAESARGMP RGQYHTMQTG FSSRSQGMSG DKTSTFRPIA KPAYSPASWS SRSAVDLTCS RRLSSAHNGG SAFGAVGYGG TQPTPPMPTR PVSFHERGGA ASRADYDTLS LPSLRLGPGG LDDRYSVVSE QLEPAAASTY RAYAYKRQAS SGSSRAGGLD WPEATEGPPS RTIRAPAMRT LQRFQSSHRS RGGTGSVSGA GLEPVARAPS VRSLSLSLAD SGHLPDVRGL DSYTGHRTLQ RLSSGFDDID LPSAVKYLMA SDPNLQVLGA AYIQHRCYSD AAAKKQARSL QAVPRLVKLF NHANQEVQRH ATGAMRNLIY DNVDNKLALV EENGIFELLR TLREQDDELR KNVTGILWNL SSSDHLKDRL ARDTLEQLTD LVLSPLSGPG GPPLIQQNAS EAEIFYNATG FLRNLSSASQ ATRQKMRECH GLVDALVTYI NHALDVGKCE DKSVENAVCV LRNLSYRLYD EMPPSALQRL EGRGRRDMAG APPGEMVGCF TPQSRRLREL PLTADALTFA EVSKDPKGLE WLWSPQIVGL YNRLLQRCEL NRHTTEAAAG ALQNITAGDR RWAGVLSRLA LEQERILNPL LDRVRTADHN QLRSLTGLIR NLSRNARNKD EMSTKVVSHL IEKLPGSVGE KCPPAEVLVN IIAVLNNLVV ASPIAARDLL YFDGLRKLVF IKKKRDSPDS EKSSRAASSL LANLWQYSKL HRDFRAKGYR KEDFLGP //