ID Q9Q9K2_9HIV1 Unreviewed; 156 AA. AC Q9Q9K2; DT 01-MAY-2000, integrated into UniProtKB/TrEMBL. DT 01-MAY-2000, sequence version 1. DT 11-DEC-2019, entry version 66. DE SubName: Full=Envelope glycoprotein {ECO:0000313|EMBL:AAF15111.1}; DE Flags: Fragment; GN Name=env {ECO:0000313|EMBL:AAF15111.1}; OS Human immunodeficiency virus 1. OC Viruses; Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus. OX NCBI_TaxID=11676 {ECO:0000313|EMBL:AAF15111.1}; OH NCBI_TaxID=9606; Homo sapiens (Human). RN [1] {ECO:0000313|EMBL:AAF15111.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=10608755; DOI=10.1086/315167; RA El Sayed N.M., Gomatos P.J., Beck-Sague C.M., Dietrich U., von Briesen H., RA Osmanov S., Esparza J., Arthur R.R., Wahdan M.H., Jarvis W.R.; RT "Epidemic transmission of human immunodeficiency virus in renal dialysis RT centers in Egypt."; RL J. Infect. Dis. 181:91-97(2000). CC -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000256|SAAS:SAAS01050327}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF155711; AAF15111.1; -; Genomic_DNA. DR GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW. DR GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell. DR GO; GO:0039663; P:membrane fusion involved in viral entry into host cell; IEA:UniProtKB-KW. DR GO; GO:0019062; P:virion attachment to host cell; IEA:UniProtKB-KW. DR Gene3D; 2.170.40.20; -; 1. DR InterPro; IPR036377; Gp120_core_sf. DR InterPro; IPR000777; HIV1_Gp120. DR Pfam; PF00516; GP120; 1. DR SUPFAM; SSF56502; SSF56502; 1. PE 4: Predicted; KW Disulfide bond {ECO:0000256|SAAS:SAAS01050261}; KW Fusion of virus membrane with host membrane KW {ECO:0000256|SAAS:SAAS01050351}; KW Host-virus interaction {ECO:0000256|SAAS:SAAS01050329}; KW Membrane {ECO:0000256|SAAS:SAAS01050265}; KW Viral attachment to host cell {ECO:0000256|SAAS:SAAS01050352}; KW Viral envelope protein {ECO:0000313|EMBL:AAF15111.1}; KW Viral penetration into host cytoplasm {ECO:0000256|SAAS:SAAS01050355}; KW Virion {ECO:0000256|SAAS:SAAS01050315}; KW Virus entry into host cell {ECO:0000256|SAAS:SAAS01050293}. FT DOMAIN 3..150 FT /note="GP120" FT /evidence="ECO:0000259|Pfam:PF00516" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:AAF15111.1" FT NON_TER 156 FT /evidence="ECO:0000313|EMBL:AAF15111.1" SQ SEQUENCE 156 AA; 17666 MW; 95786E7F3C8917A6 CRC64; KIIIVQLNES VVINCTRPNN NTRKSISIGP GKAFYTTGDI IGDIRQAHCN ISREQWNRAL NQTIGKLEEQ FRNKTIYFNQ SSGGDPEIVT HSFNCGGEFF YCNSTQLFNS TKLKNDTGTI ILPCRIKQII NMWQGVGKAM YAPPIRGQLE FHQILQ //