ID   Q9Q6V7_9HIV1            Unreviewed;       202 AA.
AC   Q9Q6V7;
DT   01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2000, sequence version 1.
DT   28-NOV-2012, entry version 57.
DE   RecName: Full=Protein Nef;
GN   Name=nef;
OS   HIV-1 CRF03_AB.
OC   Viruses; Retro-transcribing viruses; Retroviridae; Orthoretrovirinae;
OC   Lentivirus; Primate lentivirus group.
OX   NCBI_TaxID=540995;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=KAL153;
RX   MEDLINE=20386750; PubMed=10933619; DOI=10.1089/08892220050075309;
RA   Liitsola K., Holm K., Bobkov A., Pokrovsky V., Smolskaya T.,
RA   Leinikki P., Osmanov S., Salminen M.;
RT   "An AB recombinant and its parental HIV type 1 strains in the area of
RT   the former Soviet Union: low requirements for sequence identity in
RT   recombination. UNAIDS Virus Isolation Network.";
RL   AIDS Res. Hum. Retroviruses 16:1047-1053(2000).
CC   -!- SIMILARITY: Belongs to the lentivirus primate group Nef protein
CC       family.
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DR   EMBL; AF193276; AAF22322.1; -; Genomic_DNA.
DR   HSSP; P04324; 1ZEC.
DR   ProteinModelPortal; Q9Q6V7; -.
DR   SMR; Q9Q6V7; 2-201.
DR   GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0030683; P:evasion or tolerance by virus of host immune response; IEA:UniProtKB-KW.
DR   GO; GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.62.10; HIV_Nef; 1.
DR   InterPro; IPR001558; HIV_Nef.
DR   Pfam; PF00469; F-protein; 1.
DR   SUPFAM; SSF55671; HIV_Nef; 1.
PE   3: Inferred from homology;
KW   Host cell membrane; Host membrane; Host-virus interaction;
KW   Lipoprotein; Membrane; Myristate; Viral immunoevasion; Virulence.
SQ   SEQUENCE   202 AA;  23020 MW;  3B9EFBA099C97D93 CRC64;
     MGGKWSKSSI VGWPQVRERI RRAPAPAARG VGPVSQDLDK YGAVTSSNTA ANNADCAWLE
     AQEEEEVGFP VRPQVPLRPM TYKGAFDLSH FLKEKGGLDG LIYSKKRQEI LDLWVYHTQG
     YFPDWQPGIR FPLTFGWCYK LVPVDPAEVE EATEGENNSL LHPICQHGMD DEEKEVLMWK
     FDSRLALTHR ARELHPEFYK DC
//