ID CYB_SINKE Reviewed; 371 AA. AC Q9MLD7; DT 01-JUN-2001, integrated into UniProtKB/Swiss-Prot. DT 01-OCT-2000, sequence version 1. DT 01-OCT-2014, entry version 64. DE RecName: Full=Cytochrome b; DE AltName: Full=Complex III subunit 3; DE AltName: Full=Complex III subunit III; DE AltName: Full=Cytochrome b-c1 complex subunit 3; DE AltName: Full=Ubiquinol-cytochrome-c reductase complex cytochrome b subunit; GN Name=MT-CYB; Synonyms=COB, CYTB, MTCYB; OS Sinomicrurus kelloggi (Kellogg's coral snake) (Calliophis kelloggi). OG Mitochondrion. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; OC Toxicofera; Serpentes; Colubroidea; Elapidae; Elapinae; Sinomicrurus. OX NCBI_TaxID=114670; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RA Slowinski J.B., Boundy J., Lawson R.; RT "The phylogenetic relationships of Asian coral snakes (Elapidae: RT Calliophis and Maticora) based on morphological and molecular RT characters."; RL Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Component of the ubiquinol-cytochrome c reductase CC complex (complex III or cytochrome b-c1 complex), which is a CC respiratory chain that generates an electrochemical potential CC coupled to ATP synthesis. {ECO:0000250}. CC -!- COFACTOR: Binds 2 heme groups non-covalently. {ECO:0000250}. CC -!- SUBUNIT: The main subunits of complex b-c1 are: cytochrome b, CC cytochrome c1 and the Rieske protein. {ECO:0000250}. CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250}; CC Multi-pass membrane protein {ECO:0000250}. CC -!- MISCELLANEOUS: Heme 1 (or BL or b562) is low-potential and absorbs CC at about 562 nm, and heme 2 (or BH or b566) is high-potential and CC absorbs at about 566 nm. {ECO:0000250}. CC -!- SIMILARITY: Belongs to the cytochrome b family. CC {ECO:0000255|PROSITE-ProRule:PRU00967, ECO:0000255|PROSITE- CC ProRule:PRU00968}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF220408; AAF35311.1; -; Genomic_DNA. DR ProteinModelPortal; Q9MLD7; -. DR SMR; Q9MLD7; 13-368. DR HOVERGEN; HBG017694; -. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. DR GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW. DR GO; GO:0009055; F:electron carrier activity; IEA:InterPro. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro. DR GO; GO:0022904; P:respiratory electron transport chain; IEA:InterPro. DR Gene3D; 1.20.810.10; -; 1. DR InterPro; IPR005798; Cyt_b/b6_C. DR InterPro; IPR005797; Cyt_b/b6_N. DR InterPro; IPR027387; Cytb/b6-like. DR InterPro; IPR016174; Di-haem_cyt_TM. DR Pfam; PF00032; Cytochrom_B_C; 1. DR Pfam; PF13631; Cytochrom_B_N_2; 1. DR SUPFAM; SSF81342; SSF81342; 1. DR SUPFAM; SSF81648; SSF81648; 1. DR PROSITE; PS51003; CYTB_CTER; 1. DR PROSITE; PS51002; CYTB_NTER; 1. PE 3: Inferred from homology; KW Electron transport; Heme; Iron; Membrane; Metal-binding; KW Mitochondrion; Mitochondrion inner membrane; Respiratory chain; KW Transmembrane; Transmembrane helix; Transport. FT CHAIN 1 371 Cytochrome b. FT /FTId=PRO_0000060708. FT TRANSMEM 25 45 Helical. {ECO:0000255}. FT TRANSMEM 68 88 Helical. {ECO:0000255}. FT TRANSMEM 104 124 Helical. {ECO:0000255}. FT TRANSMEM 142 162 Helical. {ECO:0000255}. FT TRANSMEM 170 190 Helical. {ECO:0000255}. FT TRANSMEM 222 242 Helical. {ECO:0000255}. FT TRANSMEM 280 300 Helical. {ECO:0000255}. FT TRANSMEM 311 331 Helical. {ECO:0000255}. FT TRANSMEM 339 359 Helical. {ECO:0000255}. FT METAL 75 75 Iron 1 (heme b562 axial ligand). FT METAL 89 89 Iron 2 (heme b566 axial ligand). FT METAL 174 174 Iron 1 (heme b562 axial ligand). FT METAL 188 188 Iron 2 (heme b566 axial ligand). SQ SEQUENCE 371 AA; 42188 MW; B6723C71E03BD70F CRC64; MSNQHTLLIS NLLPVGSNIS TWWNFGSMLL TCLILQITTG FFLAIHYTAN INLAFSSVTH IMRDVPYGWI MQNLHAIGAS MFFICIYIHI ARGLYYGLYM NKNVWLSGTT LLITLMATAF FGYVLPWGQM SFWAATVITN LLTAIPYLGT TITTWLWGGF SINDPTLTRF FALHFILPFA IISLSSIHII LLHNKGSNNP LGTNSDIDKI PFHPYHSYKD TLMTISLFIL MFTILSFSPD LFNDPENFSK ANPLVTPQHI KPEWYFLFAY GILRSIPNKL GGTLALLMSV TILMTAPFTH TSHMRPMTFR PLAQMAFWTL IATFITITWT ASKPVEPPFI IISQMTSILY FLFFIMNPLL GWTENKIMMN N //