ID Q9MD82_MOUSE PRELIMINARY; PRT; 607 AA. AC Q9MD82; DT 01-OCT-2000 (TrEMBLrel. 15, Created) DT 01-OCT-2000 (TrEMBLrel. 15, Last sequence update) DT 01-FEB-2005 (TrEMBLrel. 29, Last annotation update) DE NADH-ubiquinone oxidoreductase chain 5 (EC 1.6.5.3). GN Name=ND5; OS Mus musculus (Mouse). OG Mitochondrion. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=SAMP8, SAMR1, and SAMP1; TISSUE=Liver; RA Mori M., Higuchi K., Tanaka M.; RL Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C3H/He; RA Mizutani J., Chiba T., Tanaka M., Higuchi K., Mori M.; RL Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases. RN [3] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C3H/An, and Balb/cJ; TISSUE=Connective, and Platelets; RA Acin-Perez R., Bayona-Bafaluy M., Bueno M., Machicado C., RA Fernandez-Silva P., Perez-Martos A., Montoya J., Lopez-Perez M.J., RA Sancho J., Enriquez J.A.; RT "An intragenic supressor in the cytochrome c oxidase I gene of mouse RT mitochondrial DNA."; RL Hum. Mol. Genet. 12:329-339(2003). RN [4] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C3H/An, Balb/cJ, and C57BL/6J; RC TISSUE=Connective, and Platelets; RX MEDLINE=22836051; PubMed=12954771; DOI=10.1093/nar/gkg739; RA Bayona-Bafaluy M.P., Acin-Perez R., Mullikin J.C., Park J.S., RA Moreno-Loshuertos R., Hu P., Perez-Martos A., Fernandez-Silva P., RA Bai Y., Enriquez J.A.; RT "Revisiting the mouse mitochondrial DNA sequence."; RL Nucleic Acids Res. 31:5349-5355(2003). RN [5] RP NUCLEOTIDE SEQUENCE. RC STRAIN=ALR/Lt, ALS/Lt, NOD/LtJ, and NON/Lt; RA Mathews C.E., Leiter E.H., Spirina O., Bykhovskaya Y., RA Fischel-Ghodsian N.; RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases. RN [6] RP NUCLEOTIDE SEQUENCE. RC STRAIN=ALR/Lt, ALS/Lt, NOD/LtJ, and NON/Lt; RA Gusdon A.M., Spirina O., Bykhovskaya Y., Fischel-Ghodsia N., RA Libert T., Trucco M., Mathews C.E.; RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: NADH + ubiquinone = NAD(+) + ubiquinol. CC -!- SUBCELLULAR LOCATION: Integral membrane protein, mitochondrial CC inner membrane (By similarity). CC -!- SIMILARITY: Belongs to the complex I subunit 5 family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB042809; BAA95805.1; -. DR EMBL; AB042523; BAA95663.1; -. DR EMBL; AB042524; BAA95650.1; -. DR EMBL; AB049357; BAB13811.1; -. DR EMBL; AJ489607; CAD33917.1; -. DR EMBL; AJ512208; CAD54442.1; -. DR EMBL; AY172335; AAN85132.1; -. DR EMBL; AY533105; AAS01436.1; -. DR EMBL; AY533106; AAS01449.1; -. DR EMBL; AY533107; AAS01462.1; -. DR EMBL; AY533108; AAS01475.1; -. DR GO; GO:0005739; C:mitochondrion; IEA. DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA. DR GO; GO:0016491; F:oxidoreductase activity; IEA. DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA. DR InterPro; IPR010934; NADH5_C. DR InterPro; IPR003945; NADHpl_oxred5. DR InterPro; IPR003916; NADHub_oxred5. DR InterPro; IPR001750; Oxidored_q1. DR InterPro; IPR001516; Oxidored_q1_N. DR Pfam; PF06455; NADH5_C; 1. DR Pfam; PF00361; Oxidored_q1; 1. DR Pfam; PF00662; Oxidored_q1_N; 1. DR PRINTS; PR01434; NADHDHGNASE5. DR TIGRFAMs; TIGR01974; NDH_I_L; 1. KW Mitochondrion; NAD; Oxidoreductase; Ubiquinone. SQ SEQUENCE 607 AA; 68474 MW; 31C10862CDC78B10 CRC64; MNIFTTSILL IFILLLSPIL ISMSNLIKHI NFPLYTTTSI KFSFIISLLP LLMFFHNNME YMITTWHWVT MNSMELKMSF KTDFFSILFT SVALFVTWSI MQFSSWYMHS DPNINRFIKY LTLFLITMLI LTSANNMFQL FIGWEGVGIM SFLLIGWWYG RTDANTAALQ AILYNRIGDI GFILAMVWFS LNMNSWELQQ IMFSNNNDNL IPLMGLLIAA TGKSAQFGLH PWLPSAMEGP TPVSALLHSS TMVVAGIFLL VRFHPLTTNN NFILTTMLCL GALTTLFTAI CALTQNDIKK IIAFSTSSQL GLMMVTLGMN QPHLAFLHIC THAFFKAMLF MCSGSIIHSL ADEQDIRKMG NITKIMPFTS SCLVIGSLAL TGMPFLTGFY SKDLIIEAIN TCNTNAWALL ITLIATSMTA MYSMRIIYFV TMTKPRFPPL ISINENDPDL MNPIKRLAFG SIFAGFVISY NIPPTSIPVL TMPWFLKTTA LIISVLGFLI ALELNNLTMK LSMNKANPYS SFSTLLGFFP SIIHRITPMK SLNLSLKTSL TLLDLIWLEK TIPKSTSTLH TNMTTLTTNQ KGLIKLYFMS FLINIILIII LYSINLE //